Sandra Lia do Amaral Cardoso
CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Bauru. Faculdade de Ciências (FC) (Institutional affiliation for the last research proposal) Birthplace: Brazil
graduate at Licenciatura Plena em Educação Física from Universidade de São Paulo (1991) and ph.d. at Physiology from Universidade de São Paulo (1998). Has experience in Physiology, focusing on Cardiovascular Physiology, acting on the following subjects: angiogenesis, treinamento fisico, hipertensão, microcirculation and vegf. (Source: Lattes Curriculum)
- Role of physical training on autonomic balance, arterial stiffness and rarefaction in spontaneously hypertensive rats treated with dexamethasone: role of miRNA, AP.R
Abstract
Hypertension is the main risk factor for cardiovascular diseases and has been considered an important health problem. We have previously shown that chronic dexamethasone (DEX) treatment determined hypertension; however, the responsible mechanisms are not completely elucidated. Since hypertensive individuals may have use DEX, is reasonable to think that DEX treatment would increase even ...
- The effect of physical activity on fluoride metabolism in sedentary children: a feasibility study, AV.EXT
Abstract
Many factors appear to affect fluoride metabolism, however, there is limited and often contradictory evidence from the literature on the effect of exercise on fluoride metabolism. The primary aim of Dra Liane Azevedo visit is to collect data for a feasibility trial aiming to inform the design of a full trial targeting the effect of physical activity on fluoride metabolism. Dra Azevedo w...
- Physical training effects on hypertension, arterial stiffness and muscle atrophy induced by dexamethasone: role of oxidative stress, AP.R
Abstract
Dexamethasone (DEX) is widely used in clinics due to its potent effect as anti-allergic and anti-inflammatory drug, however its chronic use may cause several metabolic and haemodynamic alterations. It has been shown that DEX treatment provokes hypertension and muscle atrophy, however the mechanisms responsible for these effects are not totally understood. We recently have shown that ren...
(Only some records are available in English at this moment)
- Exercise training effects on SHR treated with dexamethasone: role of miRNAs, BP.DR
Abstract
Hypertension (H) is a multifactorial disease characterized by high and sustained levels of blood pressure (BP), classified as primary and secondary H. Dexamethasone (DEX) is a synthetic glucocorticoid with potent anti-allergic and anti-inflammatory effects and H is one of its unwanted side-effect. Spontaneously hypertensive rats (SHR) treated with DEX may have higher mortality risk due ...
- Cardiac remodeling in spontaneously hypertensive rats: role of exercise training associated or not with perindopril, BP.IC
Abstract
Among all consequences of hypertension, cardiovascular diseases are the major contributing to mortality. Factor such cardiac hypertrophy, fibrosis and myocardium capillary density loss are involved. Spontaneously hypertensive rats (SHR) have cardiac remodeling due to hypertension and because of that, several pharmacological and non-pharmacological treatments are used. Among inhibitors o...
- Influence of aerobic physical training on cardiac remodeling of spontaneously hypertensive rats treated with dexamethasone, BP.MS
Abstract
Heart failure (HF) is one of the most deadly cardiovascular diseases in Brazil. Cardiac hypertrophy, increased fibrosis and capillary density reduction are implicated in its development. Spontaneously hypertensive rats (SHR), throughout their life, develop cardiac hypertrophy due to arterial hypertension (HA) evolution. However, little is known about dexamethasone-effects (DEX) in these...
- Effects of dexamethasone short-time treatment: role of renin-angiotensin-system and autonomic nervous system, BP.IC
Abstract
Dexamethasone (Dex) is a synthetic glucocorticoid widely used because of its potent anti-inflammatory and antiallergic effects. However when chronically administered, several side effects such as body weight loss, muscle atrophy, hyperglycemia and hyperinsulinemia, blood pressure (BP) increase, among others are present. Among the mechanism responsible for BP increase there are reduced n...
(Only some records are available in English at this moment)
- Exercise training prevents rarefaction induced by dexamethasone: role of mitochondria, BE.EP.DR
Abstract
Dexamethasone (DEX) is used as anti-inflammatory and immunosuppressant drug. DEX treatment side-effects are several including muscle weakness, hypertension and microvascular rarefaction, which is attributed to an imbalance in angiogenesis and apoptotic signaling. DEX alters mitochondrial function in muscle cells but nothing is known of DEX effects in endothelial cells that could explain...
| 8 / 7 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 18 / 11 | Completed scholarships in Brazil |
| 2 / 1 | Completed scholarships abroad |
| 29 / 20 | All research grants and scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 10 |
| Citations | 76 |
| Cit./Article | 7.6 |
| Data from Web of Science | |
AMARAL‚ S.L.; ROMAN‚ R.J.; GREENE‚ A.S.. Renin gene transfer restores angiogenesis and vascular endothelial growth factor expression in Dahl S rats. Hypertension, v. 37, n. 2, p. 386-390, 2001.
FLEURY, CAMILA A.; ANDREO, VAGNER C.; LOMBA, PEDRO C.; DIONISIO, THIAGO J.; AMARAL, SANDRA L.; SANTOS, CARLOS F.; FARIA, FLAVIO A.. Comparison of epinephrine and felypressin pressure effects in 1K1C hypertensive rats treated or not with atenolol. JOURNAL OF ANESTHESIA, v. 29, n. 1, p. 56-64, FEB 2015. Web of Science Citations: 1. (11/21522-0)
MACEDO, ANDERSON G.; KRUG, ANDRE L. O.; HERRERA, NAIARA A.; ZAGO, ANDERSON S.; RUSH, JAMES W. E.; AMARAL, SANDRA L.. Low-intensity resistance training attenuates dexamethasone-induced atrophy in the flexor hallucis longus muscle. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, v. 143, p. 357-364, SEP 2014. Web of Science Citations: 14. (12/21820-3, 11/21522-0)
KRUG, ANDRE L. O.; MACEDO, ANDERSON G.; ZAGO, ANDERSON S.; RUSH, JAMES W. E.; SANTOS, CARLOS F.; AMARAL, SANDRA L.. High-intensity resistance training attenuates dexamethasone-induced muscle atrophy. MUSCLE & NERVE, v. 53, n. 5, p. 779-788, MAY 2016. Web of Science Citations: 6. (12/21820-3, 11/21522-0)
DIONISIO, T. J.; LOUZADA, J. C. A.; VISCELLI, B. A.; DIONISIO, E. J.; MARTUSCELLI, A. M.; BAREL, M.; PEREZ, O. A. B.; BOSQUEIRO, J. R.; BROZOSKI, D. T.; SANTOS, C. F.; et al. Aerobic Training Prevents Dexamethasone-Induced Peripheral Insulin Resistance. Hormone and Metabolic Research, v. 46, n. 7, p. 484-489, JUN 2014. Web of Science Citations: 12. (08/00821-6)
HERRERA, NAIARA A.; JESUS, ISLEY; DIONISIO, EVANDRO J.; DIONISIO, THIAGO J.; SANTOS, CARLOS F.; AMARAL, SANDRA L.. Exercise Training Prevents Dexamethasone-induced Rarefaction. Journal of Cardiovascular Pharmacology, v. 70, n. 3, p. 194-201, SEP 2017. Web of Science Citations: 2. (14/23229-6)
HERRERA, NAIARA A.; JESUS, ISLEY; SHINOHARA, ANDRE L.; DIONISIO, THIAGO J.; SANTOS, CARLOS F.; AMARAL, SANDRA L.. Exercise training attenuates dexamethasone-induced hypertension by improving autonomic balance to the heart, sympathetic vascular modulation and skeletal muscle microcirculation. Journal of Hypertension, v. 34, n. 10, p. 1967-1976, OCT 2016. Web of Science Citations: 5. (14/18177-7, 14/23229-6)
CONSTANTINO, PAULA B.; DIONISIO, THIAGO J.; DUCHATSCH, FRANCINE; HERRERA, NAIARA A.; DUARTE, JOSIANE O.; SANTOS, CARLOS F.; CRESTANI, CARLOS C.; AMARAL, SANDRA L.. Exercise attenuates dexamethasone-induced hypertension through an improvement of baroreflex activity independently of the renin-angiotensin system. Steroids, v. 128, p. 147-154, DEC 2017. Web of Science Citations: 1. (14/23050-6, 14/18177-7, 12/14376-0, 11/21522-0, 12/19722-3)
MACEDO, ANDERSON G.; KRUG, ANDRE LUIS O.; SOUZA, LIDIANE M.; MARTUSCELLI, ALINE M.; CONSTANTINO, PAULA B.; ZAGO, ANDERSON S.; RUSH, JAMES W. E.; SANTOS, CARLOS F.; AMARAL, SANDRA L.. Time-course changes of catabolic proteins following muscle atrophy induced by dexamethasone. Steroids, v. 107, p. 30-36, MAR 2016. Web of Science Citations: 10. (12/21820-3, 11/21522-0)
BAREL, MATHEUS; BROGIN PEREZ, OTAVIO ANDRE; GIOZZET, VANESSA APARECIDA; RAFACHO, ALEX; BOSQUEIRO, JOSE ROBERTO; DO AMARAL, SANDRA LIA. Exercise training prevents hyperinsulinemia, muscular glycogen loss and muscle atrophy induced by dexamethasone treatment. EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY, v. 108, n. 5, p. 999-1007, MAR 2010. Web of Science Citations: 25.
AMARAL, SANDRA L.; SILVEIRA, NEIDE P.; ZORN, TELMA M. T.; MICHELINI, LISETE C.. Exercise training causes skeletal muscle venular growth and alters hemodynamic responses in spontaneously hypertensive rats. Journal of Hypertension, v. 19, n. 5, p. 931-940, May 2001.
DUCHATSCH, FRANCINE; CONSTANTINO, PAULA B.; HERRERA, NAIARA A.; FABRICIO, MAYARA F.; TARDELLI, LIDIELI P.; MARTUSCELLI, ALINE M.; DIONISIO, THIAGO J.; SANTOS, CARLOS F.; AMARAL, SANDRA L.. Short-term exposure to dexamethasone promotes autonomic imbalance to the heart before hypertension. JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION, v. 12, n. 8, p. 605-613, AUG 2018. Web of Science Citations: 0. (14/23229-6, 14/23050-6, 15/03965-2, 12/19722-3)
S.L. AMARAL; L.S. SANCHEZ; A.J.B.A. CHANG; L.V. ROSSONI; L.C. MICHELINI. Time course of training-induced microcirculatory changes and of vegf expression in skeletal muscles of spontaneously hypertensive female rats. Brazilian Journal of Medical and Biological Research, v. 41, n. 5, p. 424-431, Maio 2008.