CV Lattes
Universidade de São Paulo (USP). Faculdade de Medicina de Ribeirão Preto (FMRP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Has experience in , focusing on Health Sciences (Source: Lattes Curriculum)
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Hematopoiesis is regulated by cytokines and growth factors. The proper action of cytokines and growth factors depends, among other factors, on the action of cytoplasmic adapter proteins such as insulin receptor substrates (IRS). The association of IRS proteins to their receptors results in IRS tyrosine phosphorylation, which creates binding sites that recruit effector proteins involved in…
Genomic sequencing in patients with myeloid malignancies resulted in the identification of several new recurrent mutations. Mutations in genes involved in epigenetic regulation, such as TET2, IDH1, IDH2 and DNMT3A has been recently described in patients with myeloid malignancies including myelodysplastic syndromes (MDS), acute myeloid leukemia (AML) and myeloproliferative diseases (MPD). …
Chronic myeloid leukemia (CML) is a hematological malignancy associated with the BCR-ABL1 fusion gene, which drives the proliferative disease phenotype by activating multiple signaling pathways. Most CML patients are successfully treated with tyrosine kinase inhibitors (TKIs) targeting BCR-ABL1. However, acquired drug resistance limits TKI efficacy in a significant subset of patients, war…
| 3 / 2 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 4 / 3 | All Scholarships |
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