CV Lattes
ResearcherID
Universidade Estadual de Campinas (UNICAMP). Instituto de Biologia (IB) (Institutional affiliation for the last research proposal) Birthplace: Brazil
B.Sc. Nutrition at Federal University of Alfenas (2004). M.Sc.Food and Nutrition at University of Campinas (2008). Ph.D Functional and Molecular Biology at University of Campinas. Postdoctoral Research Fellow at Columbia University (2013-20014). Currently position as Postdoctoral Fellow at Obesity and Comorbidities Research Center, University of Campinas. Research field: Endocrine Physiology, focusing on: insulin secretion and signaling, dyslipidemia, obesity and diabetes. (Source: Lattes Curriculum)
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Changes in cellular cholesterol levels may contribute to beta cell dysfunction. Islets from LDL receptor knockout mice (LDLR-/-) possess higher cholesterol content, showing impaired calcium handling and lower insulin secretion than wild type (WT) mice. The endogenous cholesterol synthesis occurs through a series of enzymatic reactions known as the Mevalonate pathway. When activated, this …
Changes in cellular cholesterol levels may contribute to B cell dysfunction. Islets from LDL receptor knockout mice (LDLR-/-) possess higher cholesterol content, showing impaired calcium handling, lower expression of proteins that promotes granule extrusion and lower insulin secretion than wild type (WT) mice. The endogenous cholesterol synthesis occurs through a series of enzymatic react…
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