Abstract
Haemophilia A is a genetic X-linked disorder caused by the coagulation factor VIII (FVIII)deficiency. It affects 1 in 5,000 male births and is manifested by spontaneous bleeding or following trauma. The current treatment is the replacement therapy with plasma derived FVIII (pdFVIII) or recombinant FVIII (rFVIII). Despite the advantages of using rFVIII when compared to pdFVIII, as the lowe…