Abstract
Zika is a disease caused by a zika virus (ZKV) transmitted by Aedes aegypti mosquitoes, which also transmit dengue and chikungunya. The ZKV is able to reach the placenta, amniotic fluid and may cause neurological abnormalities such as fetal microcephaly, but the mechanisms remain to be elucidated. Various factors such as danger associated molecular pattern (DAMP) as the HMGB-1 (High mobil…