CV Lattes
Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Rafael Tagé Biaggio in research grants and scholarships supported by FAPESP.
| News published in Agência FAPESP Newsletter about the researcher |
| TITULO |
| Articles published in other media outlets (0 total): |
| More itemsLess items |
| VEICULO: TITULO (DATA) |
| VEICULO: TITULO (DATA) |
Mammalian cell lines are the most used system for the production of recombinant therapeutic proteins, since they are capable of performing post-translational modifications and protein folding in an authentic manner, thus producing recombinant protein with appropriate quality. Due to the growing demand for these products and the high cost and complexity of manufacturing processes, biopharm…
The main advantage of using mammalian cells as expression system consists in the fact that these cells are capable of performing post translational modifications as well as protein folding in an authentic way, thus generating a protein with correct therapeutic quality. Nevertheless, a major limitation of using this technology, in comparison to microbial expression system, is the high cost…
Human coagulation factor VII (FVII) is a vitamin K-dependent glycoprotein that plays an important role in the blood coagulation process, being one of the key molecules involved in blood clot formation. Currently, the commercial product is produced in a murine cell line, BHK-21, which gives disadvantages considering the complexity of post-translational modifications of this protein. Murine…
| 2 / 2 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 3 / 3 | All Scholarships |
| Associated processes | |