Abstract
The bacterial plaque has been identified as an etiological agent in the pathogenesis of the periodontal disease (PD). The NOD-like receptors (NLRs) are cytoplasmic proteins that sense microbial byproducts released by invasive bacteria. There is no data in the literature describing the role of NLRs in osteoclastogenesis. Since periodontopathogenic bacteria are able to invade and colonize s…