graduation at Odontologia from Universidade Federal da Paraíba (2007), master's at Odontology from Universidade Estadual Paulista Júlio de Mesquita Filho (2010) and doctorate at Odontology from Universidade Estadual Paulista Júlio de Mesquita Filho (2014). Has experience in Odontology, acting on the following subjects: microbiologia, odontologia preventiva, fitoterapia, dentística and crianças. (Source: Lattes Curriculum)
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Organ-on-a-chip has emerged as a tool to improve the predictive power of preclinical analyses through an accurate in vitro representation of human physiology, in many cases replacing animal experimentation. This application is achieved through the convergence of the fields of microfabrication, microfluidics and tissue engineering. Thus, this project proposes the development of three organ…
Tissue Engineering has emerged as an exciting field in Regenerative Medicine to propose alternative methods to regenerate tissues and organs using innovative biofabrication and cell culture methods. Three-dimensional (3D) printing has opened incredible possibilities to provide precise internal and external shape control of biomaterials. In this project, we propose the translation of addit…
The regeneration of mineralized tissues under degenerative inflammatory stimulus is a challenging situation, since the reparative potential of resident stem cells may be negatively influenced in the presence of high dosage of pro-inflammatory mediators. In this research project, an association of tissue engineering techniques will be evaluated in order to develop macro-porous chitosan sca…
Regenerating pulp tissue is challenging due to anatomical irregularities and individual variations, leading to limited efficacy of conventional treatments. This highlights the need for new, minimally invasive therapeutic approaches and the development of adaptable materials that not only precisely fit the defect site but also promote the migration and differentiation of resident pulp and …
Currently, new treatment modalities are being sought to stimulate the regeneration of the dentin-pulp complex within a minimally invasive context by applying materials that adapt perfectly to the defect and stimulate resident pulp and apical papilla cells to migrate into the material and differentiate, resulting in the deposition of new tissue, which is called cell homing therapy. Therefo…
This project aims the development of bioprinting strategies to obtain porous and bioactive scaffolds based on gelatin methacrylate (GelMA) associated to metallic oxides, personalized to bone defects. In phase 1, two bioprinting technologies will be tested to obtain GelMA scaffold containing a porous and interconnected internal microarchitecture. The effectiveness of these technologies to …
(Only some records are available in English at this moment)
Currently, the development of biomaterials into Regenerative Dentistry has been into the spotlight, being studied in association with tissue engineering concepts. Novel technologies have been developed to aid dentin regeneration, by creating from novel biomaterials a favorable environment for dental pulp cells proliferate and differentiate, leading to pulp-dentin complex regeneration. Thi…
Currently, new treatment options have been investigated to stimulate tissue regeneration within minimally invasive concept, by applying a biomaterial that perfectly shape in defected area and capable of stimulating resident cells from pulp and apical papilla to migrate for material's surface and differentiate to produce a new tissue, what is referred as cell homing therapy. Therefore, the…
Dentin and pulp regeneration remains as a clinical challenge due to irregular anatomical shape observed among patients, which may interfere with success rate, and lead to low regenerative potential when commonly available treatments are applied. In this way, new treatment options have been investigated to stimulate tissue regeneration within minimally invasive concept, by applying a bioma…
(Only some records are available in English at this moment)
Applying tissue engineering strategies to modulate tertiary dentinogenesis has emerged as a promising approach to improve success rate in local dentin regeneration. Scaffolds with nanofiber architecture are capable of increasing the odontoblastic phenotype expression of dental pulp stem cells (DPSCs) due to the similarity with natural extracellular matrix. Additionally, nanofibrous mats c…
In this study, the odontoblastic differentiation of dental pulp stem cells (DPSCs) and their potential to deposit mineralized matrix after being seeded on nanofibrous scaffolds treated or not with bioactive molecules will be assessed. For this purpose, Poli (L-latic acid) nanofibrous scaffolds (NF-PLLA) and nanofibrous hollow microspheres from star-shaped PLLA (HNF-SSPLLA) will be fabric…
| 1 / 1 | Ongoing grants |
| 2 / 2 | Completed research grants |
| 5 / 5 | Ongoing scholarships in Brazil |
| 23 / 23 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 33 / 33 | All research grants and scholarships |
| Associated processes | |
CV Lattes
ORCID