- Research Grants
Natália Ketelut Carneiro in research grants and scholarships supported by FAPESP.
The severity of Paracoccidioidomycosis (PCM), systemic granulomatous disease, caused by fungus Paracoccidioides brasiliensis, is related to the properties of the infectious agent, as well as the mechanisms of host defense. The resolution of the infection involves the production of T helper (Th) 1 cytokines (IL-12, IL-18 and IFN-³). Importantly, the development of an appropriate immune r...
Paracoccidioidomycosis (PCM) is a chronic systemic disease with granulomatous alterations, caused by Paracoccidioides brasiliensis. The host defense to pulmonary infection is mediated by the secretion of several antimicrobial proteins by lung epithelium and phagocytic activity of resident alveolar macrophages. Signaling pathways of the phagocytic cellular system can be activated by vari...
The fungus Paracoccidioides brasiliensis is sensed by the Toll-like receptors 2, 4 (TLR2, 4) and dectin-1. The fungal recognition by dectin-1 is essential for NF-kB activation and induction of the expression of pro-IL-1B. The expression, maturation and secretion of IL-1B are processes tightly controlled. A major inflammatory pathway involved in the release of this cytokine is the activa...
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
|Data from Web of Science|
(References retrieved automatically from State of São Paulo Research Institutions)
CARNEIRO, Natália Ketelut. Modulação da resposta imune contra Paracoccidioides brasiliensis pelas vias canônica e não canônica do inflamassoma: participação da IL-1β, IL-18 e IL-1α no controle da infecção. Tese (Doutorado) - Faculdade de Medicina de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto. (13/21295-9)