Abstract
Nonfunctioning pituitary adenomas (NFPA) are the most frequent pituitary tumors. These tumors received this definition because they do not result in anterior pituitary hormonal hypersecretion or a clinical hormone-excess syndrome, and their diagnosis rests on the clinical recognition of compressive symptoms. Somatostatin (SRIF) and dopamine (DA) are two critical regulators of pituitary ce…