Abstract
The RSKs (RSK1-4) are a family of kinases constituted by four human isoforms (RSK 1- 4) directly regulated by the Ras-ERK1/2 pathway. The RSKs regulate several cellular functions, such as proliferation and the control of transcription and translation. The deregulation of RSKs seems to be responsible for different oncogenic outcomes in several types of tumors. Nevertheless, the function of…