CV Lattes
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Universidade de São Paulo (USP). Instituto de Física (IF) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Química Bacharelado from Universidade Estadual de Maringá (2011) and doctorate at Ciências from Universidade de São Paulo (2017). Has experience in Chemistry, acting on the following subjects: clorofilas, micela, ligação., fotossensibilizadores, oxigênio singlete, clorofilas and estabilidade. (Source: Lattes Curriculum)
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Generating reactive oxygen species (ROS) in specific intracellular targets is the best strategy to maximize the Photodynamic Therapy (PDT) efficiency, since the short lifetime and high reactivity limited the ROS distribution inside cells. During years literature indicated mitochondria as target-organelle for PDT, however reports more recents indicate lysosomes as organelle-key to enhanced…
Photochemical Internalization (PCI) can revolutionize the drug or biomolecules delivery inside eukaryotic cells. This concept is grounded on the use of photosensitizers (PS), which localize mainly in endocytic vesicles membrane, it is photo-damaged and enable the release of lumem endocytic vesicles membrane into citosol. PCI has been risen the protocols efficiency in the cancer therapy. M…
Photodynamic Therapy (PDT) is a treatment that use of the photosensitizer (PS) and light irradiation in the appropiate wavelength, inducing the photo-oxidation of biomolecules. Porphyrins photosensitizers has been widely used in PDT due appropriate characteristics to this treatment. It is know that addition the photochemical properties, the photo-activity of this compounds depends prefere…
| 3 / 3 | Completed scholarships in Brazil |
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