Rafael Scaf de Molon
CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Araraquara. Faculdade de Odontologia (FOAr) (Institutional affiliation for the last research proposal) Birthplace: Brazil
bachelor's at Odontologia from Universidade do Sagrado Coração (2004) and master's at Periodontology from Universidade Estadual Paulista Júlio de Mesquita Filho (2012). Has experience in Odontology, focusing on Odontology, acting on the following subjects: implante osseointegrado, estética, abutments, doença periodontal and recessão gengival. (Source: Lattes Curriculum)
- A potentially new class of bone-protective drugs, phytocystatin from sweet orange Csin-CPI-2, as possible therapeutic candidate for treatment of bone diseases, BP.PD
Abstract
Recently, a number of studies have pointed to a potential relationship between rheumatoid arthritis (RA) and periodontal disease (PD) driven in part by the common features shared by both diseases. Both RA and PD present similarities in the inflammatory pathways, in the imbalance between pro- and anti-inflammatory cytokines, and are associated with bone destruction mediated by inflammato...
- Phytocystatins Csin-CPI-2 as a possible therapeutic candidate for treatment of periodontal disease and rheumatoid arthritis, BP.IC
Abstract
Recently, a number of studies have pointed to a potential relationship between rheumatoid arthritis (RA) and periodontal disease (PD) driven in part by the common features shared by both diseases. Both RA and PD present similarities in the inflammatory pathways, in the imbalance between pro- and anti-inflammatory cytokines, and are associated with bone destruction mediated by inflammato...
- A new therapeutic approach to inhibit bone loss using phytocystatin Csin-CPI-2 for the treatment of metabolic bone diseases, BP.IC
Abstract
Recently, a number of studies have pointed to a potential relationship between rheumatoid arthritis (RA) and periodontal disease (PD) driven in part by the common features shared by both diseases. Both RA and PD present similarities in the inflammatory pathways, in theimbalance between pro- and anti-inflammatory cytokines, and are associated with bone destruction mediated by inflammator...
- Evaluation among rheumatoid arthritis, periodontal disease and bisphosphonates to induce osteonecrosis of the jaws in mice, BP.DR
Abstract
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease characterized by a persistent synovitis, systemic inflammation, and autoantibodies that can lead to long-term joint damage, resulting in chronic pain, loss of function and disability. The link between periodontal disease (PD) and RA has primarily been based on pathophysiologic mechanisms shared by both disorders, spe...
- Periodontitis and rheumatoid arthritis - association, dual treatment and resolution, BE.EP.PD
Abstract
Rheumatoid arthritis (RA) and periodontitis (PD) are prevalent chronic conditions associated with significant morbidity. Both conditions are characterized by chronic inflammation and local tissue destruction. Evidence from our and other groups indicates that RA and PD not only often concur, but may also have a shared etiopathogenesis. The production of inflammatory and microbial particl...
| 1 / 1 | Ongoing scholarships in Brazil |
| 3 / 3 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 5 / 5 | All Scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 9 |
| Citations | 167 |
| Cit./Article | 18.6 |
| Data from Web of Science | |
BOAS NOGUEIRA, ANDRESSA VILAS; DE MOLON, RAFAEL SCAF; NOKHBEHSAIM, MARJAN; DESCHNER, JAMES; CIRELLI, JONI AUGUSTO. Contribution of biomechanical forces to inflammation-induced bone resorption. Journal of Clinical Periodontology, v. 44, n. 1, p. 31-41, JAN 2017. Web of Science Citations: 19. (10/07771-4, 11/13752-5)
DE MOLON, RAFAEL SCAF; MASCARENHAS, VINICIUS IBIAPINA; DE AVILA, ERICA DORIGATTI; FINOTI, LIVIA SERTORI; TOFFOLI, GUSTAVO BOZE; PALOMARI SPOLIDORIO, DENISE MADALENA; SCAREL-CAMINAGA, RAQUEL MANTUANELI; TETRADIS, SOTIRIOS; CIRELLI, JONI AUGUSTO. Long-term evaluation of oral gavage with periodontopathogens or ligature induction of experimental periodontal disease in mice. CLINICAL ORAL INVESTIGATIONS, v. 20, n. 6, p. 1203-1216, JUL 2016. Web of Science Citations: 14. (12/11860-8)
DE MOLON, RAFAEL SCAF; CHEONG, SIMON; BEZOUGLAIA, OLGA; DRY, SARAH M.; PIRIH, FLAVIA; CIRELLI, JONI AUGUSTO; AGHALOO, TARA L.; TETRADIS, SOTIRIOS. Spontaneous osteonecrosis of the jaws in the maxilla of mice on antiresorptive treatment: A novel ONJ mouse model. BONE, v. 68, p. 11-19, NOV 2014. Web of Science Citations: 27. (12/09968-5)
DE MOLON, RAFAEL SCAF; SHIMAMOTO, HIROAKI; BEZOUGLAIA, OLGA; PIRIH, FLAVIA Q.; DRY, SARAH M.; KOSTENUIK, PAUL; BOYCE, ROGELY W.; DWYER, DENISE; AGHALOO, TARA L.; TETRADIS, SOTIRIOS. OPG-Fc but Not Zoledronic Acid Discontinuation Reverses Osteonecrosis of the Jaws (ONJ) in Mice. Journal of Bone and Mineral Research, v. 30, n. 9, p. 1627-1640, SEP 2015. Web of Science Citations: 24. (12/09968-5)
DE MOLON, RAFAEL SCAF; THURLINGS, ROGIER M.; WALGREEN, BIRGITTE; HELSEN, MONIQUE M.; VAN DER KRAAN, PETER M.; CIRELLI, JONI AUGUSTO; KOENDERS, I, MARIJE. Systemic Resolvin E1 (RvE1) Treatment Does Not Ameliorate the Severity of Collagen-Induced Arthritis (CIA) in Mice: A Randomized, Prospective, and Controlled Proof of Concept Study. Mediators of Inflammation, v. 2019, OCT 31 2019. Web of Science Citations: 0. (15/21697-5, 16/09876-4)
DE MOLON, RAFAEL SCAF; ROSSA, JR., CARLOS; THURLINGS, ROGIER M.; CIRELLI, JONI AUGUSTO; KOENDERS, MARIJE I.. Linkage of Periodontitis and Rheumatoid Arthritis: Current Evidence and Potential Biological Interactions. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 20, n. 18, SEP 2 2019. Web of Science Citations: 1. (15/21697-5, 16/09876-4)
BOAS NOGUEIRA, ANDRESSA VILAS; CHAVES DE SOUZA, JOAO ANTONIO; DE MOLON, RAFAEL SCAF; MARIANO PEREIRA, ELYNE DA SILVA; DE AQUINO, SABRINA GARCIA; GIANNOBILE, WILLIAM V.; CIRELLI, JONI AUGUSTO. HMGB1 Localization during Experimental Periodontitis. Mediators of Inflammation, 2014. Web of Science Citations: 13. (10/05957-3)
DE MOLON, RAFAEL SCAF; HSU, CHINGYUN; BEZOUGLAIA, OLGA; DRY, SARAH M.; PIRIH, FLAVIA Q.; SOUNDIA, AKRIVOULA; CUNHA, FERNANDO QUEIROZ; CIRELLI, JONI AUGUSTO; AGHALOO, TARA L.; TETRADIS, SOTIRIOS. Rheumatoid Arthritis Exacerbates the Severity of Osteonecrosis of the Jaws (ONJ) in Mice. A Randomized, Prospective, Controlled Animal Study. Journal of Bone and Mineral Research, v. 31, n. 8, p. 1596-1607, AUG 2016. Web of Science Citations: 9. (12/09968-5)
DE AQUINO, SABRINA G.; ABDOLLAHI-ROODSAZ, SHAHLA; KOENDERS, MARIJE I.; VAN DE LOO, FONS A. J.; PRUIJN, GER J. M.; MARIJNISSEN, RENOUD J.; WALGREEN, BIRGITTE; HELSEN, MONIQUE M.; VAN DEN BERSSELAAR, LIDUINE A.; DE MOLON, RAFAEL S.; et al. Periodontal Pathogens Directly Promote Autoimmune Experimental Arthritis by Inducing a TLR2-and IL-1-Driven Th17 Response. JOURNAL OF IMMUNOLOGY, v. 192, n. 9, p. 4103-4111, MAY 1 2014. Web of Science Citations: 60. (08/08142-0, 09/00341-7)
(References retrieved automatically from State of São Paulo Research Institutions)
MOLON, Rafael Scaf de. Patofisiologia de osteonecrose induzida por bisfosfonatos e inibidores de RANK-L. 2016. 123f. Tese (Doutorado) – . Universidade Estadual Paulista "Júlio de Mesquita Filho" Faculdade de Odontologia (Campus de Araraquara).