CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Botucatu. Faculdade de Ciências Agronômicas (FCA) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Dr. Jayme Souza-Neto holds a bachelor degree in Biology from Northern Rio de Janeiro State University (UENF, 2002) and PhD in Genetics from São Paulo State University Institute of Biosciences (IBB/UNESP, 2006). Dr. Souza-Neto has a Postdoctoral training at the Johns Hopkins Bloomberg School of Public Health (2008-2011) in the field of vector-pathogen interactions functional genomics. He currently is an Assistant Professor at the Department of Bioprocesses and Biotechnology and coordinates the Vector Functional Genomics & Microbiology Laboratory (Vectomics) from the UNESP Institute of Biotechnology (Botucatu). Dr. Souza-Neto is also affiliated to Keele University and Imperial College London as Visiting Lecturer and Visiting Researcher, respectively. Dr. Souza-Neto studies vector-pathogens interactions focusing on the identification of genes and bacteria to block the transmission of human pathogens. He coordinates research activities with British groups under the FAPESP-Keele and FAPESP-Imperial college cooperative agreements. His work has been published in prestigious scientific magazines such as Nature, Science, PNAS and PLoS journals. He is a FAPESP Young Leader (STS forum 2014) and Young Investigator Awardee since 2013, actively acting in national and British funding agencies? scientific panels (FAPESP, Confap, MRC-UK, Newton Fund). Dr. Souza-Neto is a member of the São Paulo State Zika Network and the coordinator of the UNESP Arboviroses Network. Since 2016 Dr. Souza-Neto integrates the Board of the Zika Research Program under the FAPESP?s Board of Scientific Directors. (Source: Lattes Curriculum)
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Due to sanitary risks associated with the presence of the Asian tiger mosquito Ae. albopictus in urban areas, better knowledge is needed to disentangle factors related to human-induced environmental changes favoring its proliferation in cities. While mosquito ecology has been fairly well investigated, there is still little information on its associated microbiota. However, those microorga…
Our long-term general objective is to test the potential impact of drought on the mosquito immune response to pathogens and gut microbiota. To do so we will combine experimental manipulations of hydric stress with infections with Dengue virus (DENV) in the Yellow Fever mosquito Aedes aegypti. The mosquito stress and immune response and changes in its gut microbiota will then be described …
Aedes aegypti and Aedes albopictus are both dengue vectors found in Brazil but display completely different ecology: A. aegypti is essentially an urban mosquito, with preference for artificial breeding sites, strictly anthropophilic and with high capacity to transmit dengue. On the other hand, A. albopictus can be found in urban and rural environments, breeds on both artificial and natura…
(Only some records are available in English at this moment)
Aedes aegypti is the main vector of arboviruses in the world, causing high impact on the sanitary and public health sector. In the last years of the twentieth century, arboviroses showed a dramatic emergence in different countries of the globe, showing the insufficiency of control methods based, mainly, on chemical and physical control, in an attempt to prevent the mosquito proliferation.…
The dengue virus is a flavivirus (Flaviviridae family) transmitted in Brazil by Aedes aegypti. In South America, after the reincidence of the vector in the 1970s, most Brazilian states reported DENV infection, including local transmission from the late 1980s. Arbovirus transmission is directly influenced by the mosquito vector competence, which is defined as the vector permissiveness to i…
(Only some records are available in English at this moment)
CRISPR-Cas9 is the most accurate genetic engineering tool that is currently in use to knockout genes. The VigLab, led by Professor George Christophides, has been playing a leadership in developing CRISPR-Cas9-based constructs which express Cas9 and sgRNAs to drive highly specific knockouts and/or knockins of target genes. The VigiLab is currently funded by the Bill and Melinda Gates Found…
To deal with the risk of infection caused by exposure to various microbes, insects have developed an immune system compound with a variety of defense mechanisms working in synergy. Recent unpublished studies developed in our laboratory, under the FAPESP-Keele network, with Ae. aegypti population with different levels of susceptibility to DENV4 revealed that these populations have differen…
This is a collaborative research initiative under the scope of the Memorandum of Understanding and the Cooperative Agreement signed by Keele University and FAPESP. It involves knowledge transfer and training on the CRISPR-Cas9 genome-editing tool. This will be essential for the establishment of a similar mutagenesis platform at IBTEC and elevate the impact of the research on vector-borne …
| 8 / 6 | Completed research grants |
| 13 / 10 | Completed scholarships in Brazil |
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| 24 / 19 | All research grants and scholarships |
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