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José Carlos Quilles Junior

CV Lattes ResearcherID ORCID


Universidade de São Paulo (USP). Instituto de Química de São Carlos (IQSC)  (Institutional affiliation for the last research proposal)
Birthplace: Brazil

Chemist with Master's degree in Chemistry and Ph. D. student in Organic and Biological Chemistry at Universty of São Paulo, Brazil, with 12 months at the University of Nottingham - UK. My experience is based on the evaluation of new cysteine protease (CP) inhibitors against cancer cells and some parasites aiming the evaluation of cytostatic and cytotoxic effects on these cell systems. For trying to improve their activity, the encapsulation of these inhibitors into apoferritin nanocages as performed as a drug delivery system and their bioactivity, as well as the cysteine protease inhibition inside the live cell were evaluated. During all my Ph. D. I have been working with cell assays, with large experience in cell culture and many different assays and analysis (such as flow cytometry, confocal microscopy and western blot). (Source: Lattes Curriculum)

Scholarships in Brazil
Scholarships abroad
FAPESP support in numbers * Updated January 18, 2020
Total / Available in English
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Keywords used by the researcher
Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (4)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Publications4
Citations31
Cit./Article7.8
Data from Web of Science

QUILLES JUNIOR, JOSE CARLOS; FERRAREZI, ANA LUCIA; BORGES, JANAINA PIRES; BRITO, RAFAELA RODRIGUES; GOMES, ELENI; DA SILVA, ROBERTO; MANUEL GUISAN, JOSE; BOSCOLO, MAURICIO. Hydrophobic adsorption in ionic medium improves the catalytic properties of lipases applied in the triacylglycerol hydrolysis by synergism. Bioprocess and Biosystems Engineering, v. 39, n. 12, p. 1933-1943, . Web of Science Citations: 5.

QUILLES, J. C. J.; BRITO, R. R.; BORGES, J. P.; ARAGON, CC.; FERNANDEZ-LORENTED, G.; BOCCHINI-MARTINS, D. A.; GOMES, E.; DA SILVA, R.; BOSCOLO, M.; GUISAN, J. M.. Modulation of the activity and selectivity of the immobilized lipases by surfactants and solvents. Biochemical Engineering Journal, v. 93, p. 274-280, . Web of Science Citations: 24.

QUILLES JR, JOSE C.; TEZUKA, DAIANE Y.; LOPES, CARLA D.; RIBEIRO, FERNANDA L.; LAUGHTON, CHARLES A.; DE ALBUQUERQUE, SERGIO; MONTANARI, CARLOS A.; LEITAO, ANDREI. Dipeptidyl nitrile derivatives have cytostatic effects against Leishmania spp. promastigotes. Experimental Parasitology, v. 200, p. 84-91, . Web of Science Citations: 0.

QUILLES JR, JOSE C.; BERNARDI, MURILLO D. L.; BATISTA, PEDRO H. J.; SILVA, SAMELYN C. M.; ROCHA, CAMILA M. R.; MONTANARI, CARLOS A.; LEITAO, ANDREI. Biological Activity and Physicochemical Properties of Dipeptidyl Nitrile Derivatives Against Pancreatic Ductal Adenocarcinoma Cells. ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, v. 19, n. 1, p. 112-120, . Web of Science Citations: 2.

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

JUNIOR, José Carlos Quilles. Imobilização de lipases por adsorção e ligação covalente em derivados de agarose e quitosana e sua aplicação em biocatálise. 2014. 104f. Dissertação (Mestrado) - . Universidade Estadual Paulista "Júlio de Mesquita Filho" Instituto de Biociencias, Letras e Ciencias Exatas.

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