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José Carlos Quilles Junior

CV Lattes GoogleMyCitations ResearcherID ORCID

Universidade de São Paulo (USP). Faculdade de Medicina de Ribeirão Preto (FMRP)  (Institutional affiliation for the last research proposal)
Birthplace: Brazil

Chemist with Master's degree in Chemistry and Ph. D. student in Organic and Biological Chemistry at Universty of São Paulo, Brazil, with 12 months at the University of Nottingham - UK. My experience is based on the evaluation of new cysteine protease (CP) inhibitors against cancer cells and some parasites aiming the evaluation of cytostatic and cytotoxic effects on these cell systems. For trying to improve their activity, the encapsulation of these inhibitors into apoferritin nanocages as performed as a drug delivery system and their bioactivity, as well as the cysteine protease inhibition inside the live cell were evaluated. During all my Ph. D. I have been working with cell assays, with large experience in cell culture and many different assays and analysis (such as flow cytometry, confocal microscopy and western blot). (Source: Lattes Curriculum)

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Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (8)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Data from Web of Science

QUILLES, JR., JOSE C.; SHAMIM, ANWAR; TEZUKA, DAIANE Y.; BATISTA, PEDRO H. J.; LOPES, CARLA D.; DE ALBUQUERQUE, SERGIO; MONTANARI, CARLOS A.; LEITAO, ANDREI. Dipeptidyl nitrile derivatives suppress the Trypanosoma cruzi in vitro infection. Experimental Parasitology, v. 219, . Web of Science Citations: 0. (13/18009-4, 14/07292-0, 18/15904-6, 18/03985-1)

QUILLES JUNIOR, JOSE CARLOS; FERRAREZI, ANA LUCIA; BORGES, JANAINA PIRES; ROSSI, JESSIKA SOUZA; BOCCHINI, DANIELA ALONSO; GOMES, ELENI; DA SILVA, ROBERTO; BOSCOLO, MAURICIO. Ultrasound affects the selectivity and activity of immobilized lipases applied to fatty acid ethyl ester synthesis. ACTA SCIENTIARUM-TECHNOLOGY, v. 42, . Web of Science Citations: 0. (12/09054-3, 14/20504-6)

QUILLES JUNIOR, JOSE CARLOS; FERRAREZI, ANA LUCIA; BORGES, JANAINA PIRES; BRITO, RAFAELA RODRIGUES; GOMES, ELENI; DA SILVA, ROBERTO; MANUEL GUISAN, JOSE; BOSCOLO, MAURICIO. Hydrophobic adsorption in ionic medium improves the catalytic properties of lipases applied in the triacylglycerol hydrolysis by synergism. Bioprocess and Biosystems Engineering, v. 39, n. 12, p. 1933-1943, . Web of Science Citations: 4. (13/00530-0, 12/09054-3)

QUILLES JR, JOSE C.; TEZUKA, DAIANE Y.; LOPES, CARLA D.; RIBEIRO, FERNANDA L.; LAUGHTON, CHARLES A.; DE ALBUQUERQUE, SERGIO; MONTANARI, CARLOS A.; LEITAO, ANDREI. Dipeptidyl nitrile derivatives have cytostatic effects against Leishmania spp. promastigotes. Experimental Parasitology, v. 200, p. 84-91, . Web of Science Citations: 2. (13/18009-4, 14/07292-0)

QUILLES JR, JOSE C.; BERNARDI, MURILLO D. L.; BATISTA, PEDRO H. J.; SILVA, SAMELYN C. M.; ROCHA, CAMILA M. R.; MONTANARI, CARLOS A.; LEITAO, ANDREI. Biological Activity and Physicochemical Properties of Dipeptidyl Nitrile Derivatives Against Pancreatic Ductal Adenocarcinoma Cells. ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, v. 19, n. 1, p. 112-120, . Web of Science Citations: 2. (13/18009-4, 14/07292-0)

QUILLES JUNIOR, JOSE C.; ROCHO CARLOS, FERNANDA DOS REIS; MONTANARI, A.; LEITAO, ANDREI; MIGNONE, VIVIANE W.; ARRUDA, MARIA AUGUSTA; TURYANSKA, LYUDMILA; BRADSHAW, TRACEY D.. Apoferritin encapsulation of cysteine protease inhibitors for cathepsin L inhibition in cancer cells. RSC ADVANCES, v. 9, n. 63, p. 36699-36706, . Web of Science Citations: 0. (13/18009-4, 14/07292-0)

BORGES, JANAINA PIRES; QUILLES JUNIOR, JOSE CARLOS; MORENO-PEREZ, SONIA; FERNANDEZ-LORENTE, GLORIA; BOSCOLO, MAURICIO; GOMES, ELENI; DA SILVA, ROBERTO; BOCCHINI, DANIELA ALONSO; GUISAN, JOSE MANUEL. Ethyl esters production catalyzed by immobilized lipases is influenced byn-hexaneandter-amyl alcohol as organic solvents. Bioprocess and Biosystems Engineering, . Web of Science Citations: 0. (13/00530-0, 12/09054-3)

QUILLES, J. C. J.; BRITO, R. R.; BORGES, J. P.; ARAGON, CC.; FERNANDEZ-LORENTED, G.; BOCCHINI-MARTINS, D. A.; GOMES, E.; DA SILVA, R.; BOSCOLO, M.; GUISAN, J. M.. Modulation of the activity and selectivity of the immobilized lipases by surfactants and solvents. Biochemical Engineering Journal, v. 93, p. 274-280, . Web of Science Citations: 23. (13/00530-0)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

JUNIOR, José Carlos Quilles. Imobilização de lipases por adsorção e ligação covalente em derivados de agarose e quitosana e sua aplicação em biocatálise.  104 f. Dissertação (Mestrado) -  Universidade Estadual Paulista "Júlio de Mesquita Filho" Instituto de Biociencias, Letras e Ciencias Exatas.  (12/09054-3

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