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Osvaldo Augusto Brazil Esteves Sant'Anna

CV Lattes


Secretaria da Saúde (São Paulo - Estado). Instituto Butantan  (Institutional affiliation for the last research proposal)
Birthplace: Brazil

graduate at Ciências Biológicas from Universidade de São Paulo (1971), master's at Microbiology from Universidade Federal de São Paulo (1973) and ph.d. at Microbiology from Universidade Federal de São Paulo (1979). Has experience in Immunology, focusing on Imunogenetics, acting on the following subjects: high/low mice, antobody responsiveness, vírus rábico, antibody response and vacina. (Source: Lattes Curriculum)

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Nanotechnology delivers hepatitis B vaccine 
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Keywords used by the researcher
Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (25)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Publications24
Citations311
Cit./Article13.0
Data from Web of Science

MONTEIRO DE BARROS ALMEIDA, RICARDO AUGUSTO; TOSCANO OLIVO, TAYLOR ENDRIGO; MENDES, RINALDO PONCIO; CATHARINO SARTORI BARRAVIERA, SILVIA REGINA; SOUZA, LENICE DO ROSARIO; MARTINS, JOELMA GONCALVES; HASHIMOTO, MIRIAM; FABRIS, VICIANY ERIQUE; FERREIRA JUNIOR, RUI SEABRA; BARRAVIERA, BENEDITO. Africanized honeybee stings: how to treat them. Revista da Sociedade Brasileira de Medicina Tropical, v. 44, n. 6, p. 755-761, . Web of Science Citations: 15. (07/05159-7)

SCIANI, JULIANA MOZER; MARQUES-PORTO, RAFAEL; LOURENCO JUNIOR, AIRTON; ORSI, RICARDO DE OLIVEIRA; FERREIRA JUNIOR, RUI SEABRA; BARRAVIERA, BENEDITO; PIMENTA, DANIEL CARVALHO. Identification of a novel melittin isoform from Africanized Apis mellifera venom. Peptides, v. 31, n. 8, p. 1473-1479, . Web of Science Citations: 21. (07/08478-6, 07/05159-7, 07/02476-1)

MENDONCA, R. Z.; ARROZIO, S. J.; ANTONIAZZI, M. M.. MORPHOLOGICAL CHARACTERIZATION OF VERO CELL DEATH INDUCED BY NUTRIENT DEPLETION. Acta Microscópica, v. 18, n. 3, p. 204-219, . Web of Science Citations: 1.

BRIGATTE, PATRICIA; KONNO, KATSUHIRO; GUTIERREZ, VANESSA PACCIARI; SAMPAIO, SANDRA COCCUZZO; ZAMBELLI, VANESSA OLZON; PICOLO, GISELE; CURI, RUI; CURY, YARA. Peripheral kappa and delta opioid receptors are involved in the antinociceptive effect of crotalphine in a rat model of cancer pain. Pharmacology Biochemistry and Behavior, v. 109, p. 1-7, . Web of Science Citations: 8. (08/57898-0, 98/14307-9)

JARED, SIMONE G. S.; JARED, CARLOS; EGAMI, MIZUE I.; MAILHO-FONTANA, PEDRO L.; RODRIGUES, MIGUEL T.; ANTONIAZZI, MARTA M.. Functional assessment of toad parotoid macroglands: A study based on poison replacement after mechanical compression. Toxicon, v. 87, p. 92-103, . Web of Science Citations: 9. (08/57898-0)

OLMEDO, HIDEKEL; HERRERA, MARIA; ROJAS, LEONARDO; VILLALTA, MAUREN; VARGAS, MARIANGELA; LEIGUEZ, ELBIO; TEIXEIRA, CATARINA; ESTRADA, RICARDO; MARIA GUTIERREZ, JOSE; LEON, GUILLERMO; et al. Comparison of the adjuvant activity of aluminum hydroxide and calcium phosphate on the antibody response towards Bothrops asper snake venom. JOURNAL OF IMMUNOTOXICOLOGY, v. 11, n. 1, p. 44-49, . Web of Science Citations: 8. (08/57898-0)

KIMURA, LOUISE FAGGIONATO; PREZOTTO-NETO, JOSE PEDRO; LINS FERNANDES TAVORA, BIANCA DE CARVALHO; ANTONIAZZI, MARTA MARIA; KNYSAK, IRENE; GIOIA GUIZZE, SAMUEL PAULO; SANTORO, MARCELO LARAMI; BARBARO, KATIA CRISTINA. Local inflammatory reaction induced by Scolopendra viridicornis centipede venom in mice. Toxicon, v. 76, p. 239-246, . Web of Science Citations: 3. (08/57898-0)

MOREIRA, VANESSA; MAGGIO DE CASTRO SOUTO, POLLYANA CRISTINA; RAMIREZ VINOLO, MARCO AURELIO; LOMONTE, BRUNO; GUTIERREZ, JOSE MARIA; CURI, RUI; TEIXEIRA, CATARINA. A catalytically-inactive snake venom Lys49 phospholipase A(2) homolog induces expression of cyclooxygenase-2 and production of prostaglandins through selected signaling pathways in macrophages. European Journal of Pharmacology, v. 708, n. 1-3, p. 68-79, . Web of Science Citations: 6. (07/03337-5, 10/07630-1, 08/57898-0)

RAMOS‚ AT; GONÇALVES‚ LRC; RIBEIRO‚ OG; ROCHA CAMPOS‚ AC; SANT’ANNA‚ OA. Effects of Lonomia obliqua (lepidoptera‚ saturniidae) toxin on clotting‚ inflammatory and antibody responsiveness in genetically selected lines of mice. Toxicon, v. 43, n. 7, p. 761-768, .

GIANNOTTI, KARINA CRISTINA; LEIGUEZ, ELBIO; ZULIM DE CARVALHO, ANA EDUARDA; NASCIMENTO, NEIDE GALVAO; MATSUBARA, MARCIO HIDEKI; FORTES-DIAS, CONSUELO LATORRE; MOREIRA, VANESSA; TEIXEIRA, CATARINA. A snake venom group IIA PLA2 with immunomodulatory activity induces formation of lipid droplets containing 15-d-PGJ(2) in macrophages. SCIENTIFIC REPORTS, v. 7, . Web of Science Citations: 2. (11/21341-5, 13/22610-5, 08/57898-0)

TAVORA, BIANCA C. L. F.; KIMURA, LOUISE F.; ANTONIAZZI, MARTA M.; CHIARIELLO, THIAGO M.; FAQUIM-MAURO, ELIANA L.; BARBARO, KATIA C.. Involvement of mast cells and histamine in edema Scolopendra viridicornis centipede venom. Toxicon, v. 121, p. 51-60, . Web of Science Citations: 2. (08/57898-0)

COSTA, E. S.; FAIAD, O. J.; LANDGRAF, R. G.; FERREIRA, A. K.; BRIGATTE, P.; CURI, R.; CURY, Y.; SAMPAIO, S. C.. Involvement of formyl peptide receptors in the stimulatory effect of crotoxin on macrophages co-cultivated with tumour cells. Toxicon, v. 74, p. 167-178, . Web of Science Citations: 9. (08/57898-0)

ZAMBELLI, VANESSA OLZON; DE OLIVEIRA FERNANDES, ANA CAROLINA; GUTIERREZ, VANESSA PACCIARI; BATISTA FERREIRA, JULIO CESAR; PARADA, CARLOS AMILCAR; MOCHLY-ROSEN, DARIA; CURY, YARA. Peripheral Sensitization Increases Opioid Receptor Expression and Activation by Crotalphine in Rats. PLoS One, v. 9, n. 3, . Web of Science Citations: 12. (07/00135-2, 08/57898-0)

MACHADO, F. C.; ZAMBELLI, V. O.; FERNANDES, A. C. O.; HEIMANN, A. S.; CURY, Y.; PICOLO, G.. Peripheral interactions between cannabinoid and opioid systems contribute to the antinociceptive effect of crotalphine. British Journal of Pharmacology, v. 171, n. 4, SI, p. 961-972, . Web of Science Citations: 19. (09/14203-5, 10/12917-8, 08/57898-0)

BRESSAN, ELISANGELA; TOUSKA, FILIP; VETTER, IRINA; KISTNER, KATRIN; KICHKO, TATJANA I.; TEIXEIRA, NATHALIA B.; PICOLO, GISELE; CURY, YARA; LEWIS, RICHARD J.; FISCHER, MICHAEL J. M.; et al. Crotalphine desensitizes TRPA1 ion channels to alleviate inflammatory hyperalgesia. Pain, v. 157, n. 11, p. 2504-2516, . Web of Science Citations: 11. (13/07467-1, 08/57898-0, 12/51458-4, 98/14307-9)

STUGINSKI, DANIEL RODRIGUES; NAVAS, CARLOS ARTURO; DE BARROS, FABIO CURY; CAMACHO, AGUSTIN; PEREIRA WILKEN BICUDO, JOSE EDUARDO; GREGO, KATHLEEN FERNANDES; DE CARVALHO, JOSE EDUARDO. Phylogenetic analysis of standard metabolic rate of snakes: a new proposal for the understanding of interspecific variation in feeding behavior. JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTAL, v. 188, n. 2, p. 315-323, . Web of Science Citations: 2. (08/57898-0, 12/15754-8, 08/57712-4, 08/57687-0)

LOPES, PRISCILA HESS; MURAKAMI, MARIO T.; PORTARO, V, FERNANDA C.; MESQUITA PASQUALOTO, KERLY FERNANDA; VAN DEN BERG, CARMEN; TAMBOURGI, V, DENISE. Targeting Loxosceles spider Sphingomyelinase D with small-molecule inhibitors as a potential therapeutic approach for loxoscelism. Journal of Enzyme Inhibition and Medicinal Chemistry, v. 34, n. 1, p. 310-321, . Web of Science Citations: 0. (13/07467-1, 08/57898-0, 15/17053-5)

DE FREITAS, BARBARA GUIMARAES; PEREIRA, LEANDRO MARCIO; SANTA-CECILIA, FLAVIA VIANNA; HOSCH, NATALIA GABRIELE; PICOLO, GISELE; CURY, YARA; ZAMBELLI, VANESSA O.. Mitogen-Activated Protein Kinase Signaling Mediates Morphine Induced-Delayed Hyperalgesia. FRONTIERS IN NEUROSCIENCE, v. 13, . Web of Science Citations: 0. (13/07467-1, 08/57898-0)

GUTIERREZ, VANESSA P.; ZAMBELLI, VANESSA O.; PICOLO, GISELE; CHACUR, MARUCIA; SAMPAIO, SANDRA C.; BRIGATTE, PATRICIA; KONNO, KATSUHIRO; CURY, YARA. The peripheral L-arginine-nitric oxide-cyclic GMP pathway and ATP-sensitive K+ channels are involved in the antinociceptive effect of crotalphine on neuropathic pain in rats. Behavioural Pharmacology, v. 23, n. 1, p. 14-24, . Web of Science Citations: 18. (98/14307-9, 07/02478-4, 07/00135-2, 08/57898-0)

CURY, YARA; PICOLO, GISELE; GUTIERREZ, VANESSA PACCIARI; FERREIRA, SERGIO HENRIQUE. Pain and analgesia: The dual effect of nitric oxide in the nociceptive system. NITRIC OXIDE-BIOLOGY AND CHEMISTRY, v. 25, n. 3, p. 243-254, . Web of Science Citations: 124. (08/57898-0)

FERREIRA JUNIOR, RUI S.; SCIANI, JULIANA M.; MARQUES-PORTO, RAFAEL; LOURENCO JUNIOR, AIRTON; ORSI, RICARDO DE O.; BARRAVIERA, BENEDITO; PIMENTA, DANIEL C.. Africanized honey bee (Apis mellifera) venom profiling: Seasonal variation of melittin and phospholipase A(2) levels. Toxicon, v. 56, n. 3, p. 355-362, . Web of Science Citations: 38. (07/08478-6, 07/02476-1, 07/05159-7)

PIMENTA, LUCIANA DE ARAUJO; DE ALMEIDA, MAIRA ESTANISLAU S.; BRETONES, MARISA LANGEANI; CIRILLO, MARIA CRISTINA; CURI, RUI; SAMPAIO, SANDRA COCCUZZO. Crotoxin promotes macrophage reprogramming towards an antiangiogenic phenotype. SCIENTIFIC REPORTS, v. 9, . Web of Science Citations: 0. (13/17190-7, 08/57898-0, 12/51241-5)

STUGINSKI, DANIEL RODRIGUES; NAVAS, CARLOS ARTURO; DE BARROS, FABIO CURY; GREGO, KATHLEEN FERNANDES; MARTINS, MARCIO; DE CARVALHO, JOSE EDUARDO. The Role of Feeding Specialization on Post-Prandial Metabolic Rate in Snakes of the Genus Bothrops. ZOOLOGICAL SCIENCE, v. 35, n. 4, p. 373-381, . Web of Science Citations: 0. (11/50206-9, 08/57898-0, 08/57712-4, 08/57687-0)

KIMURA, L. F.; SANTOS-NETO, M.; BARBARO, K. C.; PICOLO, G.. Potamotrygon motoro stingray venom induces both neurogenic and inflammatory pain behavior in rodents. Toxicon, v. 150, p. 168-174, . Web of Science Citations: 0. (08/57898-0, 12/00166-3)

KIMURA, LOUISE FAGGIONATO; DE MOURA MATTARAIA, VANIA GOMES; PICOLO, GISELE. Distinct environmental enrichment protocols reduce anxiety but differentially modulate pain sensitivity in rats. Behavioural Brain Research, v. 364, p. 442-446, . Web of Science Citations: 3. (11/17974-2, 08/57898-0, 13/20795-8)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

LIMA, Flávia Afonso. Estudo da imunogenicidade de intimina de Escherichia coli enteropatogênica. 2004. 82f. Dissertação (Mestrado) - Instituto de Ciências Biomédicas. Universidade de São Paulo (USP). São Paulo. (01/11735-4)

Patent applications

IMMUNOGENIC COMPLEX FORMED BY VACCINAL ANTIGENS ENCAPSULATED BY NANOSTRUCTURED MESOPOROUS SILICA  CA2621373 - Cristália Produtos Químicos Farmacêuticos Ltda; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Ogari de Castro Pacheco; Osvaldo Augusto Brazil Esteves Sant'Anna; Lucildes Pita Mercuri; Jivaldo do Rosário Matos; Marcia Carvalho de Abreu Fantini - September 2006, 12

IMMUNOGENIC COMPLEX FORMED BY VACCINAL ANTIGENS ENCAPSULATED BY NANOSTRUCTURED MESOPOROUS SILICA  CN200680038399 - Cristália Produtos Químicos Farmacêuticos Ltda; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Ogari de Castro Pacheco; Osvaldo Augusto Brazil Esteves Sant'Anna; Lucildes Pita Mercuri; Jivaldo do Rosário Matos; Marcia Carvalho de Abreu Fantini - September 2006, 12

IMMUNOGENIC COMPLEX FORMED BY VACCINAL ANTIGENS ENCAPSULATED BY NANOSTRUCTURED MESOPOROUS SILICA  EP20060775036 - Cristália Produtos Químicos Farmacêuticos Ltda; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Ogari de Castro Pacheco; Osvaldo Augusto Brazil Esteves Sant'Anna; Lucildes Pita Mercuri; Jivaldo do Rosário Matos; Marcia Carvalho de Abreu Fantini - September 2006, 12

IMMUNOGENIC COMPLEX FORMED BY VACCINAL ANTIGENS ENCAPSULATED BY NANOSTRUCTURED MESOPOROUS SILICA  KR1020080047569 - Cristália Produtos Químicos Farmacêuticos Ltda; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Ogari de Castro Pacheco; Osvaldo Augusto Brazil Esteves Sant'Anna; Lucildes Pita Mercuri; Jivaldo do Rosário Matos; Marcia Carvalho de Abreu Fantini - September 2006, 12

IMMUNOGENIC COMPLEX FORMED BY VACCINAL ANTIGENS ENCAPSULATED BY NANOSTRUCTURED MESOPOROUS SILICA MX/a/2008/003460 - Cristália Produtos Químicos Farmacêuticos Ltda; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Ogari de Castro Pacheco; Osvaldo Augusto Brazil Esteves Sant'Anna; Lucildes Pita Mercuri; Jivaldo do Rosário Matos; Marcia Carvalho de Abreu Fantini - September 2006, 12

IMMUNOGENIC COMPLEX FORMED BY VACCINAL ANTIGENS ENCAPSULATED BY NANOSTRUCTURED MESOPOROUS SILICA  PCT/BR2006/000182 - Cristália Produtos Químicos Farmacêuticos Ltda; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Ogari de Castro Pacheco; Osvaldo Augusto Brazil Esteves Sant'Anna; Lucildes Pita Mercuri; Jivaldo do Rosário Matos; Marcia Carvalho de Abreu Fantini - September 2006, 12

COMPLEXO IMUNOGÊNICO FORMADO POR ANTÍGENOS VACINAIS ENCAPSULADOS POR SÍLICA MESOPOROSA NANOESTRUTURADA PI0503817-0 - Cristália Produtos Químicos Farmacêuticos Ltda; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Ogari de Castro Pacheco; Osvaldo Augusto Brazil Esteves Sant'Anna; Lucildes Pita Mercuri; Jivaldo do Rosário Matos; Marcia Carvalho de Abreu Fantini - September 2005, 12

IMMUNOGENICAL COMPLEX FORMED BY VACCINAL ANTIGENS ENCAPSULATED BY NANOSTRUCTURED MESOPOROUS SILICA US12/066,489 - Cristália Produtos Químicos Farmacêuticos Ltda; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Ogari de Castro Pacheco; Osvaldo Augusto Brazil Esteves Sant'Anna; Lucildes Pita Mercuri; Jivaldo do Rosário Matos; Marcia Carvalho de Abreu Fantini - September 2006, 12

IMMUNOGENIC COMPLEX FORMED BY VACCINAL ANTIGENS ENCAPSULATED BY NANOSTRUCTURED MESOPOROUS SILICA  ZA2008/02277 - Cristália Produtos Químicos Farmacêuticos Ltda; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Ogari de Castro Pacheco; Osvaldo Augusto Brazil Esteves Sant'Anna; Lucildes Pita Mercuri; Jivaldo do Rosário Matos; Marcia Carvalho de Abreu Fantini - September 2006, 12

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