Orlando Petrucci Jr

• Abstract

  The myocardium protection during conventional open-heart surgeries and heart harvesting for heart transplantation is of crucial important. The heart has to assume its paper as a blood pump at the end of an open-heart surgery or right after a heart implant. The majority of cardioplegic solutions employed during open-heart surgeries or/and in heart transplant are hyperkalemic, and its mecha…

  Development of cardioplegic solution for heart transplant and conventional open-heart surgeries., AP.R

• Abstract

  Despite improvements in the treatment of acute coronary syndromes, the mortality and morbidity are still high in the real world. The amount of cell death that occurs during and after myocardial ischemia is a key determinant of late outcomes following acute coronary syndromes. In accordance with the World Health Organization, myocardial ischemia is a lethal disease with high social demands…

  The diacerein properties on the left ventricle remodeling after acute myocardial infarction: experimental study, AP.R

• Abstract

  The low cardiac output syndrome is multifactorial, however the ischemic and reperfusion injury are inevitable during intra cardiac defects repair and it has important role on it. The identification of new myocardium protective strategies might reduce the incidence of low cardiac output syndrome with less mortality and morbidity. The erythropoietin (EPO) has direct cardioprotective effects…

  Role of EPO on myocardial ischemic/reperfusion injury, AP.R

(Only some records are available in English at this moment)

• Abstract

  The heart failure is a crucial public health issue with increasing incidence and prevalence. Despite the recent therapeutical advances, the congestive heart failure (CHF) mortality and morbidity remain high. The knowledge of its pathophysiology and the development of new therapies are required. The inflammatory cascade has a significant role on left ventricle (LV) remodeling in patients w…

  Diacerein effects on left ventricle remodeling in a CHF model, BP.IC

• Abstract

  Despite the improvement of the treatment of acute coronary syndromes the mortality and morbidity remain high in the clinical practice. The quantity of injuried cells during the primary ischemic event are the primary determinant of late outcome of acute myocardial infarction. The administration of statins within myocardial infarction period has been shown to reduce mortality and cardiovasc…

  Atorvastatin effects on diastolic funtion in ischemic and miocardic reperfusion model, BP.IC

• Abstract

  The low cardiac output syndrome is multifactorial, however the ischemic andreperfusion injury are inevitable during intra cardiac defects repair and it hasimportant role on it. The identification of new myocardium protective strategies mightreduce the incidence of low cardiac output syndrome with less mortality andmorbidity. The erythropoietin (EPO) has direct cardioprotective effects in …

  Reduction of myocardial dysfunction with erythropoietin (EPO) in ischemic/reperfusion neonatal model, BP.PD

(Only some records are available in English at this moment)