Abstract
Surfactant deficiency at birth, caused by premature delivery, is responsible for the development of neonatal respiratory-distress syndrome (RDS). RDS affects 50% of the neonates with gestational age between 26 and 28 weeks and 20 and 30% of neonates with 30 and 31 weeks. Since 90's, surfactant replacement therapy is the common clinical conduct. Due to its nature complexity exogenous pulmo…