- Research Grants
Douglas Adamoski completed high school in the Federal Technological University of Parana (UTFPR) and a bachelor degree on Biological Sciences from Federal University of Paraná (UFPR). Obtained his PhD in Genetics and Molecular Biology from University of Campinas (UNICAMP). (Source: Lattes Curriculum)
The genetic and metabolic particularities of tumor cells are crucial to their high rates of cell division, normally associated with an increase on glutamine consumption used for energy and cellular biosynthetic blocks (lipids, proteins and nucleic acids) production. The first step on the glutamine metabolism is performed by the glutaminase enzyme and produces glutamate. The glutaminase ...
Tumor cells in comparison to normal ones present genetic and metabolic differences that allow them to divide at surprisingly high rates. Of special interest is the large consumption of glutamine for energy production and formation of cellular biosynthetic blocks (lipids, proteins and nucleic acids). As a first step in the metabolism of glutamine, this aminoacid is converted to glutamate...
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(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
|Data from Web of Science|
(References retrieved automatically from State of São Paulo Research Institutions)
MEIRA, Douglas Adamoski. Regulação pós-transcricional da enzima glutaminase por HuR e sua relação com os altos níveis glutaminolíticos tumorais = Post-transcriptional regulation of glutaminase enzyme by HuR and its relationship with high glutaminolytic levels in tumors. Tese (Doutorado) - Universidade Estadual de Campinas, Instituto de Biologia. (14/17820-3)