- Research Grants
graduate at Bacharelado Em Ciências Biológicas from Universidade Estadual Paulista Júlio de Mesquita Filho (1996), master's at Clinical Medicine from Universidade Estadual de Campinas (2002) and ph.d. at Clinical Medicine from Universidade Estadual de Campinas (2006). Has experience in Genetics, focusing on Molecular Genetics and of Microorganisms, acting on the following subjects: mieloma múltiplo, polimorfismos, expressão gênica, análise seriada da expressão gênica (sage) and seqüenciamento. (Source: Lattes Curriculum)
Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor. Patients with GBM have a median survival of about 14 months, despite aggressive treatment. Due to the clinical and pathological heterogeneity of the GBM, there are many recent attempts to better understand and characterize these tumors at the genetic and molecular level. The goal of this study is to identify...
Epilepsy has been described as the fourth most common neurological disease, affectting until 2% of world population that represents around 50 milions of patients. The authors showed a gap in the literature regarding the evaluation of the susceptibility of the epileptic development and the characterization of genetic alterations in the epileptic tissue. Although some studies have describ...
Glioblastoma multiforme (GBM) accounts for 15-20% of neurological tumors and being considered the most aggressive. Biological heterogeneity and resistance to chemotherapy are the major obstacles facing the development of effective treatment for GBM. Several genes and signaling pathways have been identified to be responsible for the aggressive phenotype of this tumor. The NF-ºB pathway i...
Glioblastoma multiforme (GBM) represents a significant portion of neurological tumors. It is characterized by poorly differentiated neoplastic astrocytes with areas of vascular proliferation and necrosis. The survival rate of the patients is inversely proportional to the degree of the tumor, where grade IV is the most aggressive with a relatively short prognosis. Biological heterogeneit...
(Only some records are available in English at this moment)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
|Data from Web of Science|
(References retrieved automatically from State of São Paulo Research Institutions)
ORTEGA, Manoela Marques. Caracterização da expressão genica de plasmocitos em pacientes com mieloma multiplo. Tese (Doutorado) - Faculdade de Ciências Médicas. Universidade Estadual de Campinas (UNICAMP). (02/10520-7)
ORTEGA, Manoela Marques. Identificação das deleções e mutações do gene P53 em pacientes com mieloma multiplo. Dissertação (Mestrado) - Faculdade de Ciências Médicas. Universidade Estadual de Campinas (UNICAMP). (99/03248-4)