Anita Jocelyne Marsaioli

• Abstract

  Pyrrolizidine, indolizidine and quinolizidine alkaloids are natural products found in plants, insects and amphibians. Due the vast number of biological activities, these compounds became targets for development of new drugs, and their asymmetric synthesis is a recurrent challenge. Herein, we propose an unprecedented multi-enzymatic cascade reactions involving transaminases, imino reductas…

  Multi-enzymatic cascade processes for alkaloids synthesis, AP.R

• Abstract

  The Centre of Excellence for Research in Sustainable Chemistry (CERSusChem) is an initiative of researchers at the Chemistry Department of the Federal University of São Carlos, aiming to promote the development and implementation of green and sustainable chemistry and related technologies. The Centre, is formed by 18 faculty members of 5 different Public Universities (UFSCar UNICAMP, USP-…

  Green chemistry: sustainable synthetic methods employing benign solvents, safer reagents, and bio-renewable feedstock, AP.PCPE
• 22nd inter symposium on the chemistry of natural products | sao carlos - sp, AO.R

(Only some records are available in English at this moment)

• Abstract

  Alkaloids are secondary metabolites found in plants and animals displaying several biological activities making them targets for the development of new drugs. However, the big challenge is to achieve an efficient and enantioselective process to these natural products. In this way, we propose an enzymatic cascade route involving transaminases (TA), followed by a spontaneous intramolecular …

  Cascade reactions for alkaloids synthesis, BP.IC

• Abstract

  The present work aims at evaluating the enzymatic profile of yeasts and bacteria from UNICAMP collections when pure and contaminated with several viruses from the collection of Professor Clarice Arns of the IB of UNICAMP including viruses such as Zika, dengue and when possible chicungunha. The strains deposited in the collection of IQ-UNICAMP and IB UNICAMP were characterized by 16 S and …

  Synthesis of peptide probes for rapid identification of Zika Virus, BP.IC

• Abstract

  The concepts of "green chemistry" emerged in the 1990s and include, among others, selective catalysis, degradable chemicals, low toxicity and low risk products. The chemical reactions catalyzed by Enzymes generate regioselective, biodegradable products and act under mild conditions, thus being an extremely interesting and attractive alternative to traditional organic synthesis. Also, bioc…

  Green chemistry: monoamine oxidases (MAO) and imine reductases expression for piperidine synthesis, BP.PD

(Only some records are available in English at this moment)

• Abstract

  Fire ant venom are comprised by piperidine, pyrrolidine, piperideine, pyrroline, indolizidine and pyrrolizidine alkaloids. These compounds are widely reported in the literature, mainly due to their biological activities such as insecticidal, fungicidal, bactericidal and hemolytic. However, the importance of the absolute configuration to these activities has been underexploited due to the …

  Biocatalytic processes involving transaminases and imine reductases for the synthesis of ant venom alkaloids., BE.EP.PD