Abstract
Parkinson's disease (PD) is a chronic neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substantia nigra, leading to both motor and non-motor symptoms that impair quality of life (Jankovic, 2008). Periodontitis is a source of peripheral inflammation that induces the release of pro-inflammatory cytokines (TNF-¿, IL-1¿), which can cross the blood-brain barr…