Abstract
The hemoglobinopathies are a heterogeneous group of inherited diseases, including sickle cell disease and thalassemia, characterized by changes in the structure or synthesis of hemoglobin. In Brazil, it is estimated birth than 700,000 annual cases of sickle cell disease and it is believed that 10 to 20% of the population is alpha thalassemia silent carrier. In this context, neonatal scree…