Homero Pinto Vallada Filho

• Abstract

  During the last twenty years, the use of cocaine and more recently crack has both increased and spread throughout the country, becoming a severe public health problem in Brazil. In an attempt to contribute to the understanding of this complex problem, our research group has worked, for more than ten years, on molecular genetic investigations in order to identify the biological risk factor…

  Epigenetic studies in crack dependents, AP.R

• Abstract

  Prevention of depressive disorders in the elderly: in two Basic Health Units in the low income region of Butanta, in Sao Paulo city, 2,700 individuals 60 years and older, will be screened for the presence of depressive symptoms and/or clinically significant anxiety (CES-D). The subjects selected will be assessed to identify those with sub-threshold symptom levels (of depression and/or anx…

  Prevention and Treatment of Depression in Older People: A Population-Based Study, AP.TEM
• XIXth World Congress of Psychiatric Genetics, AR.EXT

(Only some records are available in English at this moment)

• Abstract

  The work aims to adapt the spiritual Anamnesis developed by the Health, Spirituality and Religiosity program used in the clinic context, for a scale. Will be conducted psychometric analyzes of reliability and validity of this new instrument, in order to extend its use, promote standarization in data collection and use in scientific research.

  Validation of Spiritual Anamnesis of Health, Spirituality and Religiosity Program (ProSER), BP.MS

• Abstract

  Bipolar disorder (BD) is a psychiatric disorder that affects nearly 1% of the general population, with onset usually in the first decades of life and characterized by episodes of manic or hypomanic mood. The emotional and financial costs for families and for society as a whole are enormous. The main biological factor for the onset of TB is its genetic component (more than 70% of the varia…

  Telomeres length assessment in families with several affected by Bipolar Disorder, BP.MS

• Abstract

  Background: The pathophysiological mechanisms of bipolar disorder are not completely clarified and several hypothesis have already been formulated including the role of monoamines, gama amino butyric acid (GABA) and glutamate. GABA is the main inhibitory neurotransmitter while glutamate is the main excitatory neurotransmitter. Genes that play a role in GABA metabolism and in the activity …

  "Genetic association study between cognitive performance, polymorphisms of GAD1/Reelin and 3T magnetic ressonance spectroscopy of GABA/glutamate in bipolar I disorder and healthy controls", BP.PD

(Only some records are available in English at this moment)