Renata F. V. Lopez holds a degree in Pharmacy-Biochemistry, a master's in Drug and Medication Sciences, and a Ph.D. in Pharmaceutical Sciences, all completed at the Ribeirão Preto School of Pharmaceutical Sciences at the University of São Paulo (FCFRP-USP). She conducted a Sandwich Doctorate at the University of Geneva, Switzerland, where she studied the transdermal penetration of drugs associated with iontophoresis, and a Postdoctoral Fellowship at the Massachusetts Institute of Technology (MIT), USA, where she focused on nanoparticulate drug delivery systems, including ultrasound-assisted penetration of drugs through complex biological membranes, such as the skin. She is a Full Professor at FCFRP-USP and heads the Center for Innovation in Nanostructured Systems and Topical Administration (NanoTop). The main focus of her research group is to investigate the transdermal and ocular permeation of drugs and the influence of nanoparticulate delivery systems and iontophoresis on this permeation.She has authored numerous scientific articles in highly selective editorial policy journals, books, book chapters, and patents. She has supervised over 30 doctoral theses and master's dissertations, guided more than 20 undergraduate research students, and supervised the work of at least 7 postdoctoral fellows. She has received several awards and honors, including two CAPES Thesis Awards in the field of Pharmacy, in 2011 and 2015, as a supervisor of the works. She coordinates projects funded by FAPESP, CNPq, and CAPES and is involved in various international collaborative projects. She was the coordinator of the Graduate Program in Pharmaceutical Sciences at FCFRP-USP from 2014 to 2018. Currently, she serves as Vice-President of the Graduate Committee at FCFRP-USP. She leads a thematic project funded by FAPESP (2023-2028), a subproject funded by INCT-NanoFarma, and participates in the collaborative international project BRICS STI COVID.She has significant international collaborations, including an agreement for dual-degree programs with Université Paris-Saclay, France, and partnerships with the University of Geneva, Switzerland, and the University of Lagos, Nigeria. She is the President of the organizing committee of CIFARP 2023, leader of the international chapter of the Controlled Release Society (CRS) in the CRS Women in Sciences, a member of the advisory board of the Brazilian Association of Pharmaceutical Sciences (ABCF), founder and member of the CRS Brazilian Local Chapter, Vice-Coordinator of the Support Center for Ocular Pathophysiology and Therapy (NAPFTO), and a member of the INCT-NanoFarma. (Source: Lattes Curriculum)
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Intelligent drug delivery systems, which release the drug as a function of a specific change in pH or the presence of an enzyme, are increasingly being studied to reduce adverse effects and increase the efficiency of treatments. Activation of this release by physical stimuli, and not only chemical or biological, provides greater control of drug release, which is well documented in the lit…
Breast cancer is the leading cause of death in Brazil and worldwide. Triple negative breast cancer (TNBC), which does not express hormone receptors, comprises 20% of the breast cancer cases and presents relapses within 3 years, approximately. However, the major cause of death in cancer is due the formation of metastases. TNBC has a high incidence of lung and brain metastases. Moreover, fe…
(Only some records are available in English at this moment)
Skin cancer is the most common type of cancer, with increasing incidence in Brazil and worldwide. Conventional therapies, such as surgery, radiotherapy, and chemotherapy, have several disadvantages, including adverse effects and aesthetic disfigurement. Photodynamic therapy (PDT) emerges as an innovative alternative, involving the administration of a photosensitizing agent followed by irr…
Alzheimer's disease (AD) is a neurodegenerative disorder, characterized by the accumulation of ²-amyloid peptide aggregates, with soluble oligomers (A²Os) being the main neurotoxic species responsible for the loss of synapses and neuronal death, leading patients to cognitive impairment and dementia. Despite scientific advances in the area, there are still no treatments to cure AD, nor def…
Sonodynamic therapy (SDT) is a new therapeutic strategy that has been studied for the treatment of tumors. The SDT involves the interaction of ultrasound, a sonosensitizing agent and molecular oxygen in the tumor, which interact and result in cell death. The mechanisms of the antitumor action of SDT have not been well understood yet. However, the frequency of ultrasound, its intensity, du…
The outbreak of the new Coronavirus disease, COVID-19, currently represents a threat to global public health. As part of a network project that seeks to use artificial intelligence and other strategies to quickly identify approved drugs to be repositioned for the treatment of COVID-19, our group is responsible for the development of the medicine for the administration of the most promisin…
Healing is the process of biologic tissue reparation, coordinated by a series of cellular and molecular events. A strategy that has been under study to accelerate the healing process is electric stimulation and that can be done by iontophoresis. Iontophoresis is a method for topical administration of drugs, in a none invasive way, that consists on the application of electric current in lo…
(Only some records are available in English at this moment)
Among skin cancers, the squamous cell carcinoma (SCC) holds the second position in frequency and is biologically more aggressive than the basocelular skin cancer. SCC over-expresses the epidermal growth factor receptor (EGFR), which is responsible for communicating extracellular signals to the nucleus and is commonly associated with bad prognosis. The interruption of the signaling cell pa…
| 1 / 1 | Ongoing research grants |
| 17 / 15 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 35 / 23 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 58 / 44 | All research grants and scholarships |
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