CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Botucatu. Instituto de Biotecnologia (IBTEC) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduate at Ciências Biológicas from Universidade de São Paulo (1991) and ph.d. at Biochemistry from Universidade de São Paulo (1996). Has experience in Parasitology, focusing on Entomology and Malacology of Parasites and Vectors, acting on the following subjects: mosquito, malária, genetica populacional, aedes aegypti and musca domestica. (Source: Lattes Curriculum)
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BSAFE BIOTECH is a technology-based company that was created and incubated at the Biotechnology Institute of the São Paulo State University "Júlio de Mesquita Filho" (UNESP) Botucatu Campus. BSAFE BIOTECH is in the process of migrating to the Botucatu Technology Park, where its operational structure and laboratories will be implemented. Considering the growing market for plant protection …
Extensive research has examined why some people have repeated Plasmodium falciparum malaria attacks in Sub-Saharan Africa while others remain free of disease most of the time. In contrast, malaria risk heterogeneity remains little studied in regions where P. vivax is the dominant species. Are repeatedly infected people in vivax malaria settings such as the Amazon just unlucky? Here we aim…
Background: In Brazil, malaria is concentrated in the Amazon Basin, where more than 99% of the annual cases are reported. The main goal of this study was to investigate the population structure and genetic association studies of the biting behavior of Nyssorhynchus (also known as Anopheles) darlingi, the major malaria vector in the Amazon region of Brazil, using low coverage genomic seque…
Aedes aegypti is the most synanthropic and anthropophilic mosquito of Culicidae. This species always cohabits with humans and is extremely opportunistic. Vector dispersal is directly related to the ability of the females on successfully finding a mate in a generally patchy urban scenario. In the present work, we investigate transcriptional changes in Ae. aegypti females during the courtsh…
Activated peroxisome proliferation receptors (PPARs) make up a subfamily of nuclear receptors. Three isoforms, encoded by separate genes, were identified so far: PPAR±, PPAR² and PPAR³. These receptors, which act as transcription factors, exhibit different functions and distributions in tissues. To date, it has been known that the genes regulated by PPARs participate mainly in the regulat…
(Only some records are available in English at this moment)
The project investigates the microbiota of the mosquito Nyssorhynchus darlingi, the primary vector of malaria in the Brazilian Amazon, focusing on its relationship with the transmission of Plasmodium. Malaria, an endemic disease in the region, is transmitted by female mosquitoes that acquire the parasite by biting infected humans. The study aims to characterize the intestinal and salivary…
Malaria is a febrile disease resulting from infection by parasites of the genus Plasmodium, with transmission carried by anopheline mosquitoes. In Brazil, the vector of greatest epidemiological importance is Nyssorhynchus darlingi, formerly taxonomically classified as Anopheles darlingi. In the national scenario, the municipality of Barcelos (AM) was the second-largest locality with malar…
Arboviruses are viruses characterized by their transmission through hematophagous arthropods, in which the viral multiplication occurs. Its transmission cycle develops between invertebrates and vertebrates as amplifying hosts. These pathogens are responsible for infectious diseases named arboviroses, a prominent target in in monitoring Brazilian public health. An important factor that cau…
Arboviruses are infectious pathologies caused by arboviruses, which are characterized by multiplying in the tissues of invertebrates - hematophagous arthropods - and are transmitted by the bite of these invertebrates to a vertebrate host. The three arboviruses of major epidemiological importance are dengue, zika and chikungunya fever, all have in commom the main vector, the mosquito Aedes…
(Only some records are available in English at this moment)
Malaria is a febrile disease caused by infection with protozoa of the genus Plasmodium and transmitted by arthropods of the genus Anopheles, with the mosquito Anopheles gambiae being the most prominent, recognized for its widespread distribution across the African continent. Regarding the transmission cycle of the disease, after the female mosquito takes a blood meal, the success of a mos…
Peroxisome Proliferator Activated Receptor alpha (PPAR±) was shown as a possible candidate gene to contribute to the genetically determined risk of Visceral Leishmaniasis (VL). In a case-control study conducted by our group in the VL endemic area of Teresina-PI-Brazil, genotypes containing the mutated 162V allele were significantly more frequent among individuals with VL than among all un…
Malaria represents an important insect-borne disease with an estimated incidence of 216 million cases occurred worldwide and 445 000 deaths globally in 2016. Several factors contribute to the severity and worsening of this illness, among which the emergence of drug-resistant parasites and insecticide-resistant mosquitoes strains. Therefore, an alternative method to control malaria and oth…
(Only some records are available in English at this moment)