CV Lattes
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Universidade São Francisco (USF). Campus Bragança Paulista (Institutional affiliation from the last research proposal) Birthplace: Brazil
Pharmacist (UNIFAL, 1989) with a Master's and Ph.D. in Science (UNICAMP, 1997). Experienced in undergraduate and graduate teaching, and in coordinating research, development, and innovation projects funded by agencies such as FAPESP, FINEP, CNPq, and CAPES. Supervised around 30 master's and doctoral theses. Research is focused on health sciences and holds professional certification in Clinical Research (INVITARE, 2020). (Source: Lattes Curriculum)
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Different rational engineering approaches based on enzyme diversity and selecting variants with improved properties have been used to improve enzyme characteristics. The use of lipases is increasingly gaining focus due to the versatility of the catalyzed reactions and their regio, chemo and enantioselectivity. Expanding the knowledge of the enantioselectivity of lipases is of great intere…
The current approach to advanced rectal adenocarcinoma involves total excision of the mesorectum associated to neoadjuvant chemo-radiotherapy. Patient response to therapy varies and knowledge of the mechanisms involved in the response is incomplete. Metabolic modifications occurring in carcinogenesis demonstrate a relationship with treatment evolution and the response to it and the latter…
During the development of carcinogenic cells, reprogramming of their metabolic pathways and other alterations occur due to cell growth and proliferation, energy sources, inflammation, tumor-related enzymatic metabolism and others. Such alterations are intimately related to lipid metabolism so that lipids become an excellent source of information on cell metabolism in tumorigenesis. Possib…
(Only some records are available in English at this moment)
In the present project we propose conducting an unprecedented study based on rational engineering of the lipase-producing species Aspergillus niger, previously studied by our group, with a view to developing new, highly enantioselective enzymes. The genome of Aspergillus includes many genes of enzymes that have yet to be investigated and therefore potentially concealing new lipases to be …
Potential biomarkers of responses to alterations stemming from the development of cancer cells can be effectively evaluated by adopting lipidomic strategies using high resolution mass spectrometry and gas chromatography techniques for a more accurate identification and broad-scale quantification of alterations in cell and plasma lipids. This proposal to conduct a systematic qualitative an…
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing grants |
| 11 / 9 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 14 / 8 | Completed scholarships in Brazil |
| 28 / 20 | All research grants and scholarships |
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