CV Lattes
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Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduate at Ciências Biológicas from Universidade Presbiteriana Mackenzie (1993), master's at Psychology from Universidade de São Paulo (1996) and ph.d. at Physiology from Universidade de São Paulo (2000). Has experience in Physiology, focusing on Neorofisiology, acting on the following subjects: nicotine, neurotransmitters, neurodegeneração, acetylcholine and visual pathways. (Source: Lattes Curriculum)
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Aging and neurodegenerative diseases share some cellular and molecular changes in the nervous system, such as composition of membranes, energy metabolism and mitochondrial dysfunction, increased production and reduced removal of reactive oxygen species, changes in subcellular processing of proteins and neuroinflammation.Alzheimer's disease (AD) is the most common form of dementia and is c…
Alzheimer's Disease (AD) is the most common form of dementia in elderly people, and is characterized by neuronal degeneration of regions related to cognitive functions. Its etiology is still unknown and age is the major risk factor, but genetic and environmental factors seem to contribute to the development and progression of the disease. Studies suggest that disturbances in glucose metab…
Neurodegenerative diseases are characterized by progressive loss of neurons in the central nervous system and, in general, have unknown etiology. Factors such as age, genetic and environmental, increased free radical formation, mitochondrial dysfunction, neuroinflammation, accumulation of neurotoxic factors, changes in the homeostasis of Ca2+ and in the energy metabolism may contribute to…
Cannabinoid system seems to be involved in modulatory functions of plasticity, neurodegeneration, and neuroprotection processes. Parkinson's disease (PD), characterized by dopaminergic neurons degeneration of the basal ganglia with motor deficiency, has been target of many studies in the context of a putative neuroprotector role of the cannabinoid system. However, literature data are conf…
(Only some records are available in English at this moment)
In the last few years, it has been suggested that deficiency and insulin resistance in the brain may be related to Alzheimer's Disease (AD), suggesting a relationship between AD and Diabetes Mellitus (DM). Besides the relationship between dysfunction of insulin signaling and AD, several studies suggest a modulation of Thyroid Hormones (TH) in insulin signaling and in the function of nervo…
The cannabinoid system has been implicated as an important neuromodulation system in several experimental models of neuronal injury both acute and chronic type, which many studies suggest a neuroprotective action. Parkinson's disease (PD), characterized by loss of dopaminergic neurons in the substantia nigra, yet its etiology is unknown. Nevertheless, several factors seem to be involved a…
Several studies have demonstrated the role of glucose as the main nutrient of the brain and showed an increase in their use in processes of learning and memory in brain regions such as the hippocampus, amygdala and prefrontal cortex. Furthermore, these studies have indicated that insulin affects several brain functions including cognition and memory. Recent evidences suggest that Alzheime…
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing research grants |
| 7 / 5 | Completed research grants |
| 12 / 5 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 21 / 12 | All research grants and scholarships |
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