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Nicola Amanda Conran Zorzetto

CV Lattes GoogleMyCitations ResearcherID ORCID


Universidade Estadual de Campinas (UNICAMP). Centro de Hematologia e Hemoterapia (HEMOCENTRO)  (Institutional affiliation for the last research proposal)
Birthplace: Inglaterra

Graduated in Biochemistry (Medical), University of Birmingham, UK (1993). Ph.D. (Biochemistry) University of Nottingham (1996). Has experience in Biochemistry, focusing on Biochemistry, specialization in the following subjects: nitric oxide, integrin, eosinophil, inflammation and neutrophil. (Source: Lattes Curriculum)

Research grants
Scholarships in Brazil
Scholarships abroad
FAPESP support in numbers * Updated October 12, 2019
Total / Available in English
Most frequent collaborators in research granted by FAPESP
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Use this Research Supported by FAPESP (BV/FAPESP) channel only to send messages referring to FAPESP-funded scientific projects.


 

 

 

 

Keywords used by the researcher
Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (16)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Publications15
Citations273
Cit./Article18.2
Data from Web of Science

PROENCA-FERREIRA, RENATA; FRANCO-PENTEADO, CARLA F.; TRAINA, FABIOLA; SAAD, SARA T. O.; COSTA, FERNANDO F.; CONRAN, NICOLA. Increased adhesive properties of platelets in sickle cell disease: roles for alpha(IIb)beta(3)-mediated ligand binding, diminished cAMP signalling and increased phosphodiesterase 3A activity. British Journal of Haematology, v. 149, n. 2, p. 280-288, . Web of Science Citations: 19. (07/50853-9)

DOMINICAL, VENINA M.; VITAL, DAIANA M.; O'DOWD, FRANK; SAAD, SARA T. O.; COSTA, FERNANDO F.; CONRAN, NICOLA. In vitro microfluidic model for the study of vaso-occlusive processes. Experimental Hematology, v. 43, n. 3, p. 223-228, . Web of Science Citations: 9. (10/18386-4, 10/17320-0)

MASCIA LOPES, FLAVIA CRISTINE; FERREIRA, REGIANE; ALBUQUERQUE, DULCINEIA MARTINS; ANTONIELLIS SILVEIRA, ANGELICA A.; COSTA, RAQUEL; SOARES, RAQUEL; COSTA, FERNANDO FERREIRA; CONRAN, NICOLA. In vitro and in vivo anti-angiogenic effects of hydroxyurea. MICROVASCULAR RESEARCH, v. 94, p. 106-113, . Web of Science Citations: 15. (08/57441-0, 09/16334-0)

ALMEIDA, CAMILA BONONI; SCHEIERMANN, CHRISTOPH; JANG, JUNG-EUN; PROPHETE, COLETTE; COSTA, FERNANDO FERREIRA; CONRAN, NICOLA; FRENETTE, PAUL S.. Hydroxyurea and a cGMP-amplifying agent have immediate benefits on acute vaso-occlusive events in sickle cell disease mice. Blood, v. 120, n. 14, p. 2879-2888, . Web of Science Citations: 39. (07/58533-3, 11/50959-7)

LANARO, C.; FRANCO-PENTEADO, C. F.; ALBUQUEQUE, D. M.; SAAD, S. T. O.; CONRAN, N.; COSTA, F. F.. Altered levels of cytokines and inflammatory mediators in plasma and leukocytes of sickle cell anemia patients and effects of hydroxyurea therapy. Journal of Leukocyte Biology, v. 85, n. 2, p. 235-242, . Web of Science Citations: 95. (07/54870-5, 08/57895-1, 07/50853-9)

SILVEIRA, ANGELICA A. A.; MAHON, OLWYN R.; CUNNINGHAM, CLARE C.; CORR, EMMA M.; MENDONCA, RAFAELA; SAAD, SARA T. O.; COSTA, FERNANDO F.; DUNNE, AISLING; CONRAN, NICOLA. S100A8 acts as an autocrine priming signal for heme-induced human M phi pro-inflammatory responses in hemolytic inflammation. Journal of Leukocyte Biology, v. 106, n. 1, p. 35-43, . Web of Science Citations: 0. (14/23170-1, 14/19173-5, 12/22048-2)

CONRAN, NICOLA; BELCHER, JOHN D.. Inflammation in sickle cell disease. CLINICAL HEMORHEOLOGY AND MICROCIRCULATION, v. 68, n. 2-3, p. 263-299, . Web of Science Citations: 10. (14/19173-5)

LOPES, FLAVIA C. M.; TRAINA, FABIOLA; ALMEIDA, CAMILA B.; LEONARDO, FLAVIA C.; FRANCO-PENTEADO, CARLA F.; GARRIDO, VANESSA T.; COLELLA, MARINA P.; SOARES, RAQUEL; OLALLA-SAAD, SARA T.; COSTA, FERNANDO F.; et al. Key endothelial cell angiogenic mechanisms are stimulated by the circulating milieu in sickle cell disease and attenuated by hydroxyurea. Haematologica, v. 100, n. 6, p. 730-739, . Web of Science Citations: 16. (08/57441-0, 09/16334-0)

ALMEIDA, CAMILA BONONI; BOTELHO SOUZA, LUCAS EDUARDO; LEONARDO, FLAVIA COSTA; MARANHAO COSTA, FABIO TRINDADE; WERNECK, CLAUDIO C.; COVAS, DIMAS TADEU; COSTA, FERNANDO FERREIRA; CONRAN, NICOLA. Acute hemolytic vascular inflammatory processes are prevented by nitric oxide replacement or a single dose of hydroxyurea. Blood, v. 126, n. 6, p. 711-720, . Web of Science Citations: 38. (11/50959-7)

NICOLA CONRAN; CAMILA BONONI ALMEIDA. Hemolytic vascular inflammation: an update. Revista Brasileira de Hematologia e Hemoterapia, v. 38, n. 1, p. 55-57, . (11/50959-7)

ANTONIELLIS SILVEIRA, ANGELICA APARECIDA; DOMINICAL, VENINA MARCELA; VITAL, DAIANA MORELLI; FERREIRA, JR., WILSON ALVES; MARANHAO COSTA, FABIO TRINDADE; WERNECK, CLAUDIO C.; COSTA, FERNANDO FERREIRA; CONRAN, NICOLA. Attenuation of TNF-induced neutrophil adhesion by simvastatin is associated with the inhibition of Rho-GTPase activity, p50 activity and morphological changes. International Immunopharmacology, v. 58, p. 160-165, . Web of Science Citations: 1. (10/19916-7, 14/19173-5, 12/22048-2)

ANTONIELLIS SILVEIRA, ANGELICA APARECIDA; DOMINICAL, VENINA MARCELA; ALMEIDA, CAMILA BONONI; CHWEIH, HANAN; FERREIRA, JR., WILSON ALVES; VICENTE, CRISTINA PONTES; MARANHAO COSTA, FABIO TRINDADE; WERNECK, CLAUDIO C.; COSTA, FERNANDO FERREIRA; CONRAN, NICOLA. TNF induces neutrophil adhesion via formin-dependent cytoskeletal reorganization and activation of beta-integrin function. Journal of Leukocyte Biology, v. 103, n. 1, p. 87-98, . Web of Science Citations: 3. (10/19916-7, 14/19173-5, 12/22048-2)

GARRIDO, VANESSA TONIN; SONZOGNI, LAURA; MTATIRO, SIANA NKYA; COSTA, FERNANDO F.; CONRAN, NICOLA; THEIN, SWEE LAY. Association of plasma CD4OL with acute chest syndrome in sickle cell anemia. CYTOKINE, v. 97, p. 104-107, . Web of Science Citations: 8. (11/17553-7, 08/57441-0, 12/22043-0, 12/50582-3)

PROENCA-FERREIRA, RENATA; BRUGNEROTTO, ANA FLAVIA; GARRIDO, VANESSA TONIN; DOMINICAL, VENINA MARCELA; VITAL, DAIANA MORELLI; REIS RIBEIRO, MARILENE DE FATIMA; DOS SANTOS, MELISSA ERCOLIN; TRAINA, FABIOLA; OLALLA-SAAD, SARA T.; COSTA, FERNANDO FERREIRA; et al. Endothelial Activation by Platelets from Sickle Cell Anemia Patients. PLoS One, v. 9, n. 2, . Web of Science Citations: 18. (08/57441-0, 09/54279-0)

CONRAN, NICOLA; TORRES, LIDIANE. cGMP modulation therapeutics for sickle cell disease. Experimental Biology and Medicine, v. 244, n. 2, p. 132-146, . Web of Science Citations: 1. (17/14594-0, 18/08010-9, 14/00984-3)

TORRES, LIDIANE; CONRAN, NICOLA. Emerging pharmacotherapeutic approaches for the management of sickle cell disease. EXPERT OPINION ON PHARMACOTHERAPY, v. 20, n. 2, p. 173-186, . Web of Science Citations: 1. (17/14594-0, 14/00984-3)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

ALMEIDA, Camila Bononi de. Caracterização das fosfodiesterases (PDE) de GMPc nas celulas de linhagem eritroide e efeitos de drogas inibidoras de PDE na produção de hemoglobina fetal. 2006. Dissertação (Mestrado) - Faculdade de Ciências Médicas. Universidade Estadual de Campinas (UNICAMP). (04/10152-3)

GARRIDO, Vanessa Tonin. Avaliação do papel das citocinas inflamatórias, LIGHT e CD40L, na inflamação mediada por plaquetas na anemia falciforme. 2014. Tese (Doutorado) – Faculdade de Ciências Médicas. Universidade Estadual de Campinas. (11/17553-7)

ALMEIDA, Camila Bononi de. Papel dos leucócitos na fisiopatologia da anemia falciforme. 2011. Tese (Doutorado) – Faculdade de Ciências Médicas. Universidade Estadual de Campinas (UNICAMP). (07/58533-3)

DOMINICAL, Venina Marcela. Propriedades adesivas e quimiotáticas dos neutrófilos de pacientes com artrite reumatoide e a influência de diferentes medicações. 2010. Dissertação (Mestrado) - Faculdade de Ciências Médicas. Universidade Estadual de Campinas (UNICAMP). (08/51345-0)

DOMINICAL, Venina Marcela. Avaliação das interações heterotípicas de neutrófilos em pacientes com anemia falciforme. 2014. Tese (Doutorado) – Faculdade de Ciências Médicas. Universidade Estadual de Campinas. (10/18386-4)

FERREIRA, Renata Proenca. Investigação de adesão plaquetaria na anemia falciforme e o papel dos nucleotideos ciclicos nesta adesão. 2009. Dissertação (Mestrado) - Faculdade de Ciências Médicas. Universidade Estadual de Campinas (UNICAMP). (06/58788-9)

SILVEIRA, Angélica Aparecida Antoniellis. Investigação das propriedades pró-inflamatórias do TNF-"alfa" e do heme em leucócitos "in vitro" e "in vivo". 2017. Tese (Doutorado) – Universidade Estadual de Campinas, Faculdade de Ciências Médicas. (12/22048-2)

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Patent applications

COMPOSIÇÃO FARMACÊUTICA PARA CONTROLE DE VASO-OCLUSÃO E SEUS USOS BR1020120161095 - Albert Einstein College of Medicine of Yeshiva University; Universidade Estadual de Campinas (UNICAMP). Fernando Ferreira Costa; Nicola Conran Zorzetto; Camila Bononi De Almeida; Paul S. Frenette - June 2012, 27

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