CV Lattes
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Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
bachelor's at Ciências Biológicas from Universidade de Santo Amaro (1980), master's at Biochemistry from Universidade de São Paulo (1988) and doctorate at Biochemistry from Universidade de São Paulo (1997). Has experience in Biochemistry, focusing on Molecular Biology, acting on the following subjects: aedes aegypti, anti-parasite genes, musca domestica, metamorfose and anopheles. (Source: Lattes Curriculum)
| Articles published in Pesquisa FAPESP Magazine about the researcher: |
| Polémica en el aire de Jacobina |
| Jacobina controversy |
| A villain with many faces |
| Un villano con muchas caras |
| A villain with many faces |
| Genetic solutions |
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The technique of releasing mosquitoes (modified or not) for population suppression requires these insects to mate. However, studies are mentioning the occurrence of a second mate, which could compromise or decrease the success of such technique. The aim of this project is to use a homozygous transgenic line (with a fluorescent marker in the eyes) to demonstrate the occurrence of the secon…
The present proposal holds the promise of developing a collaboration that will lead to novel, synergistic insights into the biology of mosquitoes and improved vector control approaches. The proposed collaboration is especially timely given the current outbreak of mosquito-borne dengue fever in the State of Sao Paulo, Brazil and the emerging threat of dengue fever in the U.S. Funds from an…
The aim of this project is based on the use of transgenic lines of Ae. aegypti, to be adding methodology of dengue control already used. The results showed that the strain OX513A reduction strategy is viable to reduce mosquitoes population. However, it is unique and can be improved. Our strategy is based on the creation and use of three strains of genetically modified Ae. aegypti. The fi…
(Only some records are available in English at this moment)
The Aedes scapularis and Aedes fluviatilis mosquitoes are currently in the process of transition from sylvan and rural environments to urban areas, developing in artificial containers. This fact can be a problem for public health, since these mosquitoes have vector capacity or vector competence for some pathogens among these arboviruses of Flaviviridae family as Yellow Fever virus (YFV). …
With the increasing number of cases of infection with arboviruses, for instance dengue and chikungunya, it is necessary to develop new techniques to combat these arboviruses. Genetic manipulation allowed the production of genetically modified mosquitoes that are capable of suppressing the wild population or prevent disease transmission. The project proposes to establish lines for populati…
When considering a mosquito release program, one of the first issues to decide is how to eliminate females. The greatest number of options might eventually be available for those who can use transgenic mosquitoes, but the inherent characteristics of the target species itself also provide possibilities for interim measures until more efficient methods can be developed. Differences in intri…
(Only some records are available in English at this moment)
A febre da dengue clássica (FDC) e a forma mais severa, febre da dengue hemorrágica (FDH), são causadas por quatro diferentes tipos sorológicos do vírus da dengue (DEN1, 2, 3 e 4) transmitidos ao homem pela picada da fêmea, principalmente, do mosquito Aedes aegypti. Nos últimos anos, a dengue tornou-se um grave problema para a saúde pública no Brasil e no mundo, com 2,5 bilhões de pessoas…
A malária tem sido causa da morte de 2 milhões de pessoas, sendo a maioria crianças. O estudo da expressão gênica diferencial de esporozoitos de P. gallinaceum durante a invasão de glândulas salivares de mosquitos deverá fornecer dados para a manipulação genética dos setores. O emprego dessas técnicas nos mosquitos transmissores de doenças visa a obtenção de métodos de combate, que em coo…