Cleopatra da Silva Planeta
CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Araraquara. Faculdade de Ciências Farmacêuticas (FCFAR) (Institutional affiliation for the last research proposal) Birthplace: Brazil
bachelor's at Farmácia Bioquímica from Universidade de São Paulo (1985), master's at Pharmacology from Universidade de São Paulo (1988) and doctorate at Pharmacology from Universidade de São Paulo (1992). He is currently full professor at Universidade Estadual Paulista Júlio de Mesquita Filho. Has experience in Pharmacology, focusing on Neuropsicopharmacology, acting on the following subjects: estresse, sensibilização comportamental, fencanfamina, cocaína and sistema dopaminérgico. (Source: Lattes Curriculum)
- Project for the Reserva Técnica Institucional of Faculdade de Ciências Farmacêuticas - UNESP, AP.RT.INST
Abstract
The aim of the present project is to describe the application plan of the School of Pharmaceutical Sciences for the grant related to the "Reserva Técnica Institucional" da Fapesp - 2014 (AU)
- Project for the Reserva Técnica Institucional da Faculdade de Ciências Farmacêuticas - UNESP, AP.RT.INST
Abstract
The aim of the present project is to describe the application plan of the School of Pharmaceutical Sciences for the grant related to the "Reserva Técnica Institucional" da Fapesp - 2013. (AU)
- Project for the "reserva técnica institucional" Faculdade de Ciências Farmacêuticas (UNESP), AP.RT.INST
Abstract
The aim of the present project is to describe the application plan of the School of Pharmaceutical Sciences for the grant related to the "reserva técnica institucional da FAPESP" - 2013. (AU)
(Only some records are available in English at this moment)
- Evaluation of the possible prophylactic role of ketamine in anxiety induced by social defeat in mice, BP.IC
Abstract
Several evidences in the literature have demonstrated the deleterious effects that acute and chronic stress can trigger in individuals. The emergence of depression and anxiety disorder are possible consequences of these effects. The social defeat (SD) stress is an animal model that can be used to investigate the effects of acute and chronic stress on anxiety-related behavior in mice sub...
- Evaluation of left and right medial prefrontal cortex glutamatergic and GABAergic neurotransmissions in ethanol-induced consumption by social defeat stress in mice, BP.PD
Abstract
The medial prefrontal cortex (mPFC) is ivolved in the modulation of different behaviors, which include those associated with the use of ethanol and response to stressors. This brain region is predominantly composed of glutamatergic neurons and GABAergic interneurons, in addition to receiving dopaminergic afferents from the ventral tegmental area. Recently, it has been proposed that the ...
- Pharmacogenetics manipulation and research of molecular changes in synapses between selectively activated neurons in the reinstatement of ethanol self-administration, BP.PD
Abstract
Learned associations play an important role in addiction. With repeated drug use, addicts learn to associate drug effects with stimuli or cues in the drug environment, such as drug paraphernalia, context, and people. Over time, these cues can promote drug craving and relapse. These drug-related cues are complex combinations of different stimuli that are recognized with a high degree of...
- Central and cardiovascular effects resulting from association between exercise and testosterone administration on ethanol drinking in rats, BP.DR
Abstract
Drug abuse is considered a major public health problem in the world. The use of anabolic-androgenic steroids (AAS)and ethanol has increased in Brazil in the last few years. Studies indicate that the combination between physic exercise, AAS and ethanol intake has consequences to the organism. Although the relevance of the topic, a comprehensive review of the literature revealed the prese...
(Only some records are available in English at this moment)
- Testing the role of the left and right medial prefrontal cortex in fear extinction and anxiety with optogenetic manipulations, BE.EP.PD
Abstract
Rats submitted to the single prolonged stress (SPS) procedure demonstrate impaired fear extinction and increased anxiety, similar to those behavioral and physiological symptoms observed in posttraumatic stress disorder (PTSD) patients. The prefrontal cortex (PFC) plays a role in the modulation of emotional memory consolidation through its interactions with other brain regions like the a...
- Elucidating the role of ribosomal translation machinery in alcohol abuse disorders, BE.EP.DR
Abstract
Alcohol abuse is a worldwide problem with concomitant medical, social and economic costs for which pharmacotherapeutic approaches are limited. As a result, most patients relapse within the first months of treatment (MILLER and HESTER, 1986; SINHA, 2011). In particular, cues that have been associated with alcohol can trigger alcohol-related memories, leading to craving and relapse to alc...
- Characterization of neural ensembles mediating nicotine withdrawal in adolescent rats, BE.EP.MS
Abstract
Tobacco is considered a licit drug in the majority of countries around the world. Adolescence is considered a risk factor for drug abuse and dependence. High rates of nicotine dependence are seen among adolescents. The withdrawal effects of nicotine are considered as an important factor related to relapse to nicotine seeking. Previous studies indicate that specific patterns of sparsely ...
| 11 / 7 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 23 / 15 | Completed scholarships in Brazil |
| 4 / 3 | Completed scholarships abroad |
| 39 / 26 | All research grants and scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 13 |
| Citations | 135 |
| Cit./Article | 10.4 |
| Data from Web of Science | |
LEAO, RODRIGO MOLINI; CRUZ, FABIO CARDOSO; MARIN, MARCELO TADEU; PLANETA, CLEOPATRA DA SILVA. Stress induces behavioral sensitization, increases nicotine-seeking behavior and leads to a decrease of CREB in the nucleus accumbens. Pharmacology Biochemistry and Behavior, v. 101, n. 3, p. 434-442, MAY 2012. Web of Science Citations: 12. (08/01744-5, 08/10691-2)
LEAO, RODRIGO M.; CRUZ, FABIO C.; PLANETA, CLEOPATRA S.. Exposure to acute restraint stress reinstates nicotine-induced place preference in rats. Behavioural Pharmacology, v. 20, n. 1, p. 109-113, 2009. Web of Science Citations: 23. (05/02336-0)
LEPSCH‚ LB; GONZALO‚ LA; MAGRO‚ FJB; DELUCIA‚ R.; SCAVONE‚ C.; PLANETA‚ CS. Exposure to chronic stress increases the locomotor response to cocaine and the basal levels of corticosterone in adolescent rats. ADDICTION BIOLOGY, v. 10, n. 3, p. 251-256, 2005.
SANTOS, GABRIELA C.; MARIN, MARCELO T.; CRUZ, FABIO C.; DELUCIA, ROBERTO; PLANETA, CLEOPATRA S.. Amphetamine- and nicotine-induced cross-sensitization in adolescent rats persists until adulthood. ADDICTION BIOLOGY, v. 14, n. 3, p. 270-275, 2009. Web of Science Citations: 23.
ENGI, SHEILA A.; PLANETA, CLEOPATRA S.; CRESTANI, CARLOS C.. Effect of Voluntary Ethanol Consumption Combined with Testosterone Treatment on Cardiovascular Function in Rats: Influence of Exercise Training. PLoS One, v. 11, n. 1, JAN 13 2016. Web of Science Citations: 4. (13/09715-2, 12/14376-0, 12/14723-1)
C.S. PLANETA; M.T. MARIN. Effect of cocaine on periadolescent rats with or without early maternal separation. Brazilian Journal of Medical and Biological Research, v. 35, n. 11, p. 1367-1371, Nov. 2002.
CRUZ, FABIO C.; MARIN, MARCELO TADEU; LEAO, RODRIGO MOLINI; PLANETA, CLEOPATRA S.. Stress-induced cross-sensitization to amphetamine is related to changes in the dopaminergic system. JOURNAL OF NEURAL TRANSMISSION, v. 119, n. 4, p. 415-424, APR 2012. Web of Science Citations: 15. (07/08087-7)
LEAO, RODRIGO M.; CRUZ, FABIO C.; CARNEIRO-DE-OLIVEIRA, PAULO E.; ROSSETTO, DANIELLA B.; VALENTINI, SANDRO R.; ZANELLI, CLESLEI F.; PLANETA, CLEOPATRA S.. Enhanced nicotine-seeking behavior following pre-exposure to repeated cocaine is accompanied by changes in BDNF in the nucleus accumbens of rats. Pharmacology Biochemistry and Behavior, v. 104, p. 169-176, MAR 2013. Web of Science Citations: 7. (08/10691-2, 11/07469-9)
CRUZ, FABIO C.; LEAO, RODRIGO M.; MARIN, MARCELO T.; PLANETA, CLEOPATRA S.. Stress-induced reinstatement of amphetamine-conditioned place preference and changes in tyrosine hydroxylase in the nucleus accumbens in adolescent rats. Pharmacology Biochemistry and Behavior, v. 96, n. 2, p. 160-165, AUG 2010. Web of Science Citations: 10.
JUSTO, C. C.; CARNEIRO-DE-OLIVEIRA, P. E.; DELUCIA, R.; AIZENSTEIN, M. L.; PLANETA, C. S.. Repeated exposure of adolescent rats to oral methylphenidate does not induce behavioral sensitization or cross-sensitization to nicotine. Brazilian Journal of Medical and Biological Research, v. 43, n. 7, p. 651-656, JUL 2010. Web of Science Citations: 6. (05/02356-0)
ZANCHETA, ROBERTA; POSSI, ANA P. M.; PLANETA, CLEOPATRA S.; MARIN, MARCELO T.. Repeated administration of caffeine induces either sensitization or tolerance of locomotor stimulation depending on the environmental context. PHARMACOLOGICAL REPORTS, v. 64, n. 1, p. 70-77, JAN-FEB 2012. Web of Science Citations: 12. (08/01744-5)
ARAUJO‚ A.P.N.; DELUCIA‚ R.; SCAVONE‚ C.; PLANETA‚ C.S.. Repeated predictable or unpredictable stress: effects on cocaine-induced locomotion and cyclic AMP-dependent protein kinase activity. Behavioural Brain Research, v. 139, n. 1, p. 75-81, 2003.
MARIN‚ M.T.; CRUZ‚ F.C.; PLANETA‚ C.S.. Chronic restraint or variable stresses differently affect the behavior‚ corticosterone secretion and body weight in rats. Physiology & Behavior, v. 90, n. 1, p. 29-35, 2007.
MARIN‚ M. T.; PLANETA‚ C. S.. Maternal separation affects cocaine-induced locomotion and response to novelty in adolescent‚ but not in adult rats. Brain Research, v. 1013, n. 1/2, p. 83-90, 2004.
CRUZ‚ F.C.; DELUCIA‚ R.; PLANETA‚ C.S.. PRECLINICAL STUDY: Effects of chronic stress on nicotine-induced locomotor activity and corticosterone release in adult and adolescent rats. ADDICTION BIOLOGY, v. 13, n. 1, p. 63-69, 2008. (01/11880-4)
ZAGO, A.; LEAO, R. M.; CARNEIRO-DE-OLIVEIRA, P. E.; MARIN, M. T.; CRUZ, F. C.; PLANETA, C. S.. Effects of simultaneous exposure to stress and nicotine on nicotine-induced locomotor activation in adolescent and adult rats. Brazilian Journal of Medical and Biological Research, v. 45, n. 1, p. 33-37, JAN 2012. Web of Science Citations: 4. (01/11880-4)
MUNHOZ‚ C.D.; GLEZER‚ I.; KAWAMOTO‚ E.M.; ARAÚJO‚ A.P.N.; LEPSCHA‚ L.B.; PLANETA‚ C.S.; DELUCIA‚ R.; SCAVONE‚ C.. Changes in sodium‚ potassium-ATPase induced by repeated fencamfamine: the roles of cyclic AMP-dependent protein kinase and the nitric oxide-cyclic GMP pathway. Neuropharmacology, v. 45, n. 8, p. 1151-1159, 2003.
MARIN, MARCELO T.; CRUZ, FABIO C.; PLANETA, CLEOPATRA S.. Cocaine-induced behavioral sensitization in adolescent rats endures until adulthood: Lack of association with GluR1 and NR1 glutamate receptor subunits and tyrosine hydroxylase. Pharmacology Biochemistry and Behavior, v. 91, n. 1, p. 109-114, NOV 2008. Web of Science Citations: 16.
ENGI, SHEILA A.; CRUZ, FABIO C.; CRESTANI, CARLOS C.; PLANETA, CLEOPATRA S.. Cross-sensitization between testosterone and cocaine in adolescent and adult rats. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE, v. 46, p. 33-37, NOV 2015. Web of Science Citations: 3. (10/04737-0)
CARNEIRO DE OLIVEIRA, PAULO E.; LEAO, RODRIGO M.; BIANCHI, PAULA C.; MARIN, MARCELO T.; PLANETA, CLEOPATRA DA SILVA; CRUZ, FABIO C.. Stress-Induced Locomotor Sensitization to Amphetamine in Adult, but not in Adolescent Rats, Is Associated with Increased Expression of Delta FosB in the Nucleus Accumbens. FRONTIERS IN BEHAVIORAL NEUROSCIENCE, v. 10, SEP 12 2016. Web of Science Citations: 0. (07/08087-7)
RODRIGO M LEÃO; FÁBIO C CRUZ; CLEOPATRA S PLANETA. Prior exposure to stress delays extinction but does not modify reinstatement of nicotine-induced conditioned place preference. Psychology & Neuroscience, v. 3, n. 1, p. -, Jun. 2010. (05/02336-0)
(References retrieved automatically from State of São Paulo Research Institutions)
MUNHOZ, Egberto. Administração subcrônica de nicotina modifica as respostas neuroendócrina e neuroquímica induzidas pelo teste de natação forçada. 91 f. Tese (Doutorado) - Programa Interinstitucional de Pós-Graduação em Ciências Fisiológicas. Universidade Federal de São Carlos. São Carlos. (06/59924-3)
POSSI, Ana Paula Marques. Efeitos comportamentais e neuroquímicos agudos da cafeína em ratos adolescentes e adultos. 73 f. Dissertação (Mestrado) - Programa Interinstitucional de Pós-Graduação em Ciências Fisiológicas. Universidade Federal de São Carlos. São Carlos. (07/57541-2)
ZANCHETA, Roberta. Modulação contexto-específica dos efeitos comportamentais e neuroquímicos decorrentes da cafeína. 62 f. Dissertação (Mestrado) - Programa Interinstitucional de Pós-Graduação em Ciências Fisiológicas. Universidade Federal de São Carlos. São Carlos. (07/57542-9)