CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Araçatuba. Faculdade de Odontologia (FOA) (Institutional affiliation for the last research proposal) Birthplace: Brazil
Graduate at Ciências Biológicas Modalidade Médica from Universidade Federal do Estado do Rio de Janeiro (1988), master's at Cellular and Molecular Biology (Pharmacology) from Fundação Oswaldo Cruz (1994) and PhD at Pharmacology from Universidade de São Paulo (1998). Has experience in Pharmacology, acting on the following subjects: mechanisms involved in the Inflammation, periodontal disease, cytokines, chemokines, fibroblasts and systemic diseases. (Source: Lattes Curriculum)
In dentistry, there is growing interest in understanding the relationship between the inflammatory response and bone metabolism, especially regarding chronic and infectious diseases. The exploration of possible interactions between oral and systemic health has been shown to be relevant for enabling the understanding of modulators of the inflammatory process, such as the renin-angiotensin …
Professor Maria Helena Raposo Fernandes will give a course called metabolism and bone regeneration that is part of all subjects of the Multicenter Graduate Program in Physiological Sciences. This course is held every two years, and in 2012 Professor Maria Helena was in the Faculty of Dentistry of Araçatuba teaching the course for the first time. This visit was made at my request, since in…
Dental pulp is persistently affected by environmental insults along human life. The repair ability of the dental pulp is limited and the mechanisms involved in this biological event are not completely understood. MicroRNAs are molecules responsible for the tight regulation of protein synthesis. The aim of this project is to investigate the role of microRNAs in dental pulp repair. Primary …
Studies have shown that chronic stress may influence the cancer development and progression. Recent research from our laboratory in an in vitro model showed strong evidence that stress hormones may directly affect the human squamous cell carcinoma (OSCC) cells behavior. To deepen understanding of this possible association, the proposal of this study is evaluate the effects of chronic stre…
(Only some records are available in English at this moment)
Periodontal disease (PD) is considered an inflammation that destroys the tissue supporting the teeth - alveolar bone, periodontal ligament, cementum and gums. There are several studies that link periodontitis to diabetes mellitus, since diabetes mellitus increases the severity of PD. One of the mediators involved in the inflammatory process of PD is angiotensin. The renin-angiotensin syst…
Periodontal disease (PD) is an inflammatory disorder of the teeth surrounding and supporting tissues. Although the microbial etiological factor is determinant, PD progression depends on a dynamic pathogen-host interaction and may be aggravated by pre-existing systemic diseases such as hypertension, with a high probability of coexistence with PD, as they share several risk factors. In addi…
Periodontal inflammation is associated with many systemic diseases, being called periodontal medicine, among them, cardiovascular diseases, diabetes (DM) and osteoporosis. Periodontitis (PD) is an inflammatory and infectious process of the ligament and alveolar bone that support the teeth where the release of inflammatory mediators occurs. Periodontitis involves local involvement of the r…
Over the past years, possible correlations between periodontal disease (PD) and systemic diseases such as cardiovascular diseases, obesity, lung diseases and diabetes have been studied and pointed out. There is consistent evidence that severe periodontitis negatively affects glycemic control, so it is worth noting that in diabetics there is a direct relationship between periodontitis seve…
Arterial hypertension and osteoporosis represent multifactorial disorders, where genetic and environmental factors culminate in the development of pathogenesis. Recent studies suggest that angiotensin II, the main active peptide produced by the renin-angiotensin system (RAS), stimulates osteoclast differentiation and activity, influencing bone metabolism and contributing to the imbalance …
(Only some records are available in English at this moment)
Recent studies demonstrate that the stress hormone norepinephrine (NE) exerts a pivotal role in the progression and in the chemoresistance of different types of cancer but its epigenetic mechanisms remain poorly understood. Moreover, the participation of cancer stem cells (CSC) in such processes is also a mystery. In fact, those questions have not been addressed in head and neck squamous …
| 1 / 1 | Ongoing research grants |
| 14 / 7 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 40 / 22 | Completed scholarships in Brazil |
| 2 / 1 | Completed scholarships abroad |
| 60 / 34 | All research grants and scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 12 |
| Citations | 46 |
| Cit./Article | 3.8 |
| Data from Web of Science | |
BALERA BRITO, VICTOR GUSTAVO; CHAVES-NETO, ANTONIO HERNANDES; DE BARROSA, THAMINE LANDIM; PENHA OLIVEIRA, SANDRA HELENA. Soluble yerba mate (Ilex Paraguariensis) extract enhances in vitro osteoblastic differentiation of bone marrow-derived mesenchymal stromal cells. Journal of Ethnopharmacology, v. 244, NOV 15 2019. Web of Science Citations: 0. (11/06070-5, 11/19458-1, 12/20547-1)
PENHA OLIVEIRA, SANDRA HELENA; BALERA BRITO, VICTOR GUSTAVO; TFAILE FRASNELLI, SABRINA CRUZ; RIBEIRO, BIANCA DA SILVA; FERREIRA, MILENA NUNES; QUEIROZ, DAYANE PRISCILLA; BELTAN, CARLUCI TAIS; LARA, VANESSA SOARES; SANTOS, CARLOS FERREIRA. Aliskiren Attenuates the Inflammatory Response and Wound Healing Process in Diabetic Mice With Periodontal Disease. FRONTIERS IN PHARMACOLOGY, v. 10, JUL 4 2019. Web of Science Citations: 1. (15/03965-2, 18/04476-3, 17/05873-3, 18/04989-0)
FARIAS DE OLIVEIRA, LUIS CEZAR; DANILUCCI, TAIS MAROLATO; CHAVES-NETO, ANTONIO HERNANDES; CAMPANELLI, ANA PAULA; CARDOSO DA SILVA, TEREZA CRISTINA; PENHA OLIVEIRA, SANDRA HELENA. Tracheal Smooth Muscle Cells Stimulated by Stem Cell Factor-c-Kit Coordinate the Production of Transforming Growth Factor-1 and Fibroblast Growth Factor-2 Mediated by Chemokine (C-C Motif) Ligand 3. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH, v. 36, n. 6, p. 401-411, JUN 2016. Web of Science Citations: 2.
RODRIGUES VILARDI, BRUNA MARIA; BRAVO-CALDERON, DIEGO MAURICIO; BERNABE, DANIEL GALERA; PENHA OLIVEIRA, SANDRA HELENA; OLIVEIRA, DENISE TOSTES. VEGF-C expression in oral cancer by neurotransmitter-induced activation of beta-adrenergic receptors. TUMOR BIOLOGY, v. 34, n. 1, p. 139-143, FEB 2013. Web of Science Citations: 5. (10/06333-3)
BONATO, C. F.; DO-AMARAL, C. C. F.; BELINI, L.; SALZEDAS, L. M. P.; OLIVEIRA, S. H. P.. Hypertension favors the inflammatory process in rats with experimentally induced periodontitis. JOURNAL OF PERIODONTAL RESEARCH, v. 47, n. 6, p. 783-792, DEC 2012. Web of Science Citations: 8.
COLENCI, RENATO; DA SILVA ASSUNCAO, LUCIANA REICHERT; MOGAMI BOMFIM, SUELY REGINA; GOLIM, MARJORIE DE ASSIS; DEFFUNE, ELENICE; PENHA OLIVEIRA, SANDRA HELENA. Bone marrow mesenchymal stem cells stimulated by bFGF up-regulated protein expression in comparison with periodontal fibroblasts in vitro. ARCHIVES OF ORAL BIOLOGY, v. 59, n. 3, p. 268-276, MAR 2014. Web of Science Citations: 5.
DA SILVA ASSUNCAO, LUCIANA REICHERT; COLENCI, RENATO; FERREIRA DO-AMARAL, CARIL CONSTANTE; SONODA, CELSO KOOGI; MOGAMI BOMFIM, SUELY REGINA; OKAMOTO, ROBERTA; GOLIM, MARJORIE DE ASSIS; DEFFUNE, ELENICE; PERCINOTO, CELIO; PENHA DE OLIVEIRA, SANDRA HELENA. Periodontal Tissue Engineering After Tooth Replantation. Journal of Periodontology, v. 82, n. 5, p. 758-766, MAY 2011. Web of Science Citations: 12.
CHAVES NETO, ANTONIO H.; BRITO, VICTOR G. B.; LANDIM DE BARROS, THAMINE; DO AMARAL, CARIL C. F.; SUMIDA, DORIS H.; OLIVEIRA, SANDRA H. P.. Chronic high glucose and insulin stimulate bone-marrow stromal cells adipogenic differentiation in young spontaneously hypertensive rats. Journal of Cellular Physiology, v. 233, n. 9, p. 6853-6865, SEP 2018. Web of Science Citations: 0. (11/06070-5, 11/19458-1, 11/02558-3)
PENHA OLIVEIRA, SANDRA HELENA; CARVALHO SANTOS, VANESSA APARECIDA. Lipopolysaccharide-induced Stem Cell Factor Messenger RNA Expression and Production in Odontoblast-like Cells. JOURNAL OF ENDODONTICS, v. 38, n. 5, p. 623-627, MAY 2012. Web of Science Citations: 3.
DE BARROS, THAMINE LANDIM; BALERA BRITO, VICTOR GUSTAVO; FERREIRA DO AMARAL, CARIL CONSTANTE; CHAVES-NETO, ANTONIO HERNANDES; CAMPANELLI, ANA PAULA; PENHA OLIVEIRA, SANDRA HELENA. Osteogenic markers are reduced in bone-marrow mesenchymal cells and femoral bone of young spontaneously hypertensive rats. Life Sciences, v. 146, p. 174-183, FEB 1 2016. Web of Science Citations: 6. (11/06070-5, 12/01924-9, 11/19458-1)
DA SILVA ASSUNCAO, LUCIANA REICHERT; COLENCI, RENATO; FERREIRA DO-AMARAL, CARIL CONSTANTE; SONODA, CELSO KOOGI; MOGAMI BOMFIM, SUELY REGINA; OKAMOTO, ROBERTA; GOLIM, MARJORIE DE ASSIS; DEFFUNE, ELENICE; PERCINOTO, CELIO; PENHA DE OLIVEIRA, SANDRA HELENA. Periodontal Tissue Engineering After Tooth Replantation. Journal of Periodontology, v. 82, n. 5, p. 758-766, MAY 2011. Web of Science Citations: 12.
DE BARROS, THAMINE LANDIM; BALERA BRITO, VICTOR GUSTAVO; FERREIRA DO AMARAL, CARIL CONSTANTE; CHAVES-NETO, ANTONIO HERNANDES; CAMPANELLI, ANA PAULA; PENHA OLIVEIRA, SANDRA HELENA. Osteogenic markers are reduced in bone-marrow mesenchymal cells and femoral bone of young spontaneously hypertensive rats. Life Sciences, v. 146, p. 174-183, FEB 1 2016. Web of Science Citations: 6. (12/01924-9, 11/19458-1, 11/06070-5)
(References retrieved automatically from State of São Paulo Research Institutions)
BARROS, Thamine Landim de. Estudo dos mecanismos envolvidos no processo de diferenciação em linhagem osteogênica de celuas-tronco mesenquimais da medula óssea de ratos Wistar e ratos espontaneamente hipertensos (SHR). 75 f. Dissertação (Mestrado) - Universidade Estadual Paulista "Júlio de Mesquita Filho" Faculdade de Odontologia (Campus de Araçatuba). (12/01924-9)
SANTOS, Vanessa Aparecida Carvalho. Estudo dos mecanismos envolvidos na expressão de fator de crescimento de células progenitoras e fator de crescimento para fibroblastos-2 por odontoblastos estimulados por lipopolissacarídeos via p4244, p38 e PI3K. 72 f. Tese (Doutorado) - Faculdade de Odontologia de Araçatuba. Universidade Estadual Paulista. Araçatuba. (08/51486-2)
AMARAL, Caril Constante Ferreira Do. Estudo do fenótipo osteoblástico em células-tronco mesenquimais de ratos normotensos e espontaneamente hipertensos na presença ou não de doença periodontal. 150 f. Dissertação (Mestrado) - Universidade Estadual Paulista "Júlio de Mesquita Filho" Faculdade de Odontologia (Campus de Araçatuba). (10/14590-6)
GOMES, Alessandra Cristina. Estudo dos mecanismos envolvidos na migração celular induzida pelo MTA para cavidade peritoneal de camundongos. 118 f. Dissertação (Mestrado) - Faculdade de Odontologia de Araçatuba. Universidade Estadual Paulista. Araçatuba. (05/53710-9)
TIANO, Gilberto Carlos. Estudo da expressão de MMP-2 e MMP-9 por fibroblastos gengivais de camundongos estimulados por NaF via NF-kB, p4442, p38 e PI3K. 89 f. Dissertação (Mestrado) - Faculdade de Odontologia de Araçatuba. Universidade Estadual Paulista. Araçatuba. (06/54098-8)
FREIRE, Isabelle Rodrigues. Estudo dos mecanismos envolvidos na resposta tecidual de camundongos diabéticos com doença periodontal : papel dos mastócitos. 98 f. Dissertação (Mestrado) - Faculdade de Odontologia de Araçatuba. Universidade Estadual Paulista. Araçatuba. (07/53212-4)