- Research Grants
Obtained a Barchelor of Science in Engenharia Agronômica from the University of São Paulo (1990), Master of Science in Physiology of Lactation from Michigan State University (1994; advisor: Dr. H. Allen Tucker) and PhD in Physiology of Reproduction from the University of Florida (1999; advisor: Dr. William W. Thatcher). Obtained post-doctoral training at the Université de Montréal (2009; supervisor: Dr. Bruce D. Murphy). Currently Associate Professor at the School of Veterinary Medicine and Animal Science of the University of São Paulo. Coordinator of the Graduate Program in Animal Reproduction at the University of São Paulo. Principal Investigator at the Laboratory of Physiology and Molecular Endocrinology. Research focus in endocrine, cellular and molecular mechanisms controlling reproductive processes, with emphasis in ruminant pre-implantation uterine biology and strategies to increase conception rates. (Source: Lattes Curriculum)
|News published in Agência FAPESP Newsletter about the researcher|
|Study could help raise the bovine pregnancy success rate|
In cattle, needed increases in the reproductive efficiency depend on a greater understanding of the endocrine, cellular and molecular mechanisms that result in higher conception rates. The central thesis of this project is that there is a "molecular signature" associated with optimal conditions of maternal receptivity to the embryo. Such signature is defined by a hallmark profile of abu...
(Only some records are available in English at this moment)
Supplementing with progesterone (P4) at the beginning of diestrus increases pregnancy rates, but also anticipates the functional and structural regression of the corpus luteum (CL) which may impair the success of the strategy. We speculate that this anticipation (early luteolysis) can be prevented by the presence of the conceptus (embryo + attached membranes), which is the main agent re...
Long-acting injectable progesterone (P4) supplementation at the onset of diestrous increases the conception rate of beef cows. However, the anticipation of functional and structural regression of the corpus luteum (CL; i.e. anticipated luteolysis) has been observed, resulting in subsequent pregnancy loss in 30-50% of animals subjected to this treatment, reducing the efficacy of P4-suppl...
During bovine pregnancy, preimplantation period is critical, since the development of conceptus is fully dependent on the intrauterine environment. Proteins, carbohydrates, lipids, growth factors and ions, which are synthesized and secreted by endometrial glands and that compose the histotroph, have influence in maintaining conceptus until the time of implantation. It indicates that ut...
(Only some records are available in English at this moment)
The embryotrophic effects of supplementary progesterone (P4) are associated with changes in endometrial function that causes changes in the uterine luminal fluid (ULF). However, nature of components ULF associated with conceptus growth are largely unknown. Thus, this study aims to: (1) characterize the composition of the ULF (amino acids, proteins, carbohydrates and other) recovered on ...
There is increasing need of nonhuman primates (NHPs) for biomedical research, which generates the need of efficient methods to ensure adequate supply. The use of ARTs have overcome many of the problems encountered. The rhesus monkey (Macaca mulatta) is one of the most commonly used NHP in research. Although, there have been many advances in the application of ARTs in this species, cryop...
Development and implementation of genetic selection of dairy cattle has been the major method to improve productivity per animal; however, selection has been focused on production traits and only more recently reproduction and health traits. Moreover genetic selection for fertility traits has been slow because of use of indirect methods that are influenced more by the environment than c...
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
|Data from Web of Science|
(References retrieved automatically from State of São Paulo Research Institutions)
MARQUES, Vanessa Belentani. Atividade antiluteolítica no microambiente uterino durante o período crítico para o estabelecimento da gestação em bovinos. 2006. Tese (Doutorado) – Faculdade de Medicina Veterinária e Zootecnia. Universidade de São Paulo (USP). São Paulo.
LOUREIRO, João Gustavo Pereira. As funções do estradiol no processo da luteólise em bovinos: o estradiol estimula PGF2α através da ativação de receptores de P4 no endométrio?. 2004. Dissertação (Mestrado) - Faculdade de Medicina Veterinária e Zootecnia. Universidade de São Paulo (USP). São Paulo.
CARVALHO, Fernanda Maria de. Criopreservação de sêmen de primatas não-humanos. 2016. Tese (Doutorado) – Faculdade de Medicina Veterinária e Zootecnia. Universidade de São Paulo (USP). São Paulo.
FREIRE, Andre Fernando. Desenvolvimento de um método de microlavagem para estudo do microambiente uterino em bovinos: efeitos na função luteínica, crescimento folicular e manutenção da prenhez inicial. 2006. Dissertação (Mestrado) - Faculdade de Medicina Veterinária e Zootecnia. Universidade de São Paulo (USP). São Paulo.
MARTINS, Thiago. Efeitos luteolíticos e embriotróficos da suplementação de progesterona em bovinos de corte. 2018. Tese (Doutorado) – Faculdade de Medicina Veterinária e Zootecnia. Universidade de São Paulo (USP). Pirassununga.
RAMOS, Roney dos Santos. Efeito do ambiente endócrino peri-ovulatório na qualidade do ambiente uterino em vacas de corte: regulação no metabolismo das poliaminas, estresse oxidativo e proliferação celular. 2015. Tese (Doutorado) – Faculdade de Medicina Veterinária e Zootecnia. Universidade de São Paulo (USP). Pirassununga.
LIMA, Marcelo Cardoso de. Desenvolvimento de uma técnica cirúrgica para o monitoramento do microambiente uterino em bovinos. 2006. Dissertação (Mestrado) - Faculdade de Medicina Veterinária e Zootecnia. Universidade de São Paulo (USP). São Paulo.