- Research Grants
Associated Researcher in Vascular Biology Laboratory, Heart Institute, Universitu of Sao Paulo School of Medicine (Brazil). B.S. in Chemistry (University of Sao Paulo, 1998), M. S. in Biochemistry (University of Sao Paulo, 2004), Ph.D. in Cardiology (University of Sao Paulo, 2007). Research based on Biochemistry and Vascular Biology, focusing on the following topics: production of reactive species and nitric oxide in biological systems, NADPH oxidases, thiol-proteins, shear stress, integration of oxidative stress and endoplasmic reticulum in vascular systems. (Source: Lattes Curriculum)
The mechanisms by which NADPH oxidase complex is activated are still poorly unkown, although its importance for understanding of the redox cell signaling pathways. Recently we described that loss-of-function of protein disulfide isomerase (PDI), a chaperone superfamily of thioredoxin, decreased Nox1 NADPH oxidase isoform expression as well as reactive oxygen species (ROS) production in...
The biopolymer polyphosphate (polyP), which is ubiquitously produced in every cell and organism studied so far, has recently been shown to stabilize proteins during oxidative stress conditions and to serve as a cytoprotective modifier of amyloidogenic processes. PolyP shows a remarkable efficacy in accelerating amyloid fibril formation. By serving as effective nucleation source for vari...
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
|Data from Web of Science|