Glaucia Noeli Maroso Hajj
CV Lattes
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Fundação Antonio Prudente (FAP). A C Camargo Cancer Center (Institutional affiliation for the last research proposal) Birthplace: Brazil
bachelor's at Ciências Biológicas from Universidade de São Paulo (2000), bachelor's at Licenciatura en Ciencias Biológicas from Universidade de São Paulo (2004) and doctorate at Biochemistry from Universidade de São Paulo (2004). Has experience in Biochemistry, focusing on Molecular Biology, acting on the following subjects: prpc, vitronectina, sti1, acth and neuroproteção. (Source: Lattes Curriculum)
- Translationa control in cancer - Part II, AP.R
Abstract
Cellular processes such as proliferation and differentiation depend on the correct control of mRNA translation. It is well known that the translation of mRNAs that promote tumor growth is favored by the alteration of signaling pathways that regulate the process of protein synthesis. Thus, translational control in tumors is especially important for regulating gene expression at the level...
- Translational control in cancer, AP.R
Abstract
Cellular processes such as proliferation and differentiation are dependent on the correct control of mRNA translation. It is well known that the translation of mRNAs that promote tumor growth is favored by alterations in signaling pathways that regulate the process of protein synthesis. Thus, translational control in tumors is especially important for regulating gene expression at the l...
- Brazil-Canada workshop II on advances in the science of prion and prion-like misfolding diseases, AO.R
- Translational control in the nervous system: tumor mechanisms, AP.R
Abstract
Cellular processes such as differentiation and proliferation depend on the correct control of the translation of mRNAs, thus changes in the pathways that regulate translation may be an important part of the malignant cell transformation process. Glioblastoma multiforme (GBM) is among the most aggressive tumor types and present low response rates to chemotherapeutic agents. Thus, to eluc...
(Only some records are available in English at this moment)
- The role of IMPACT/GCN1/GCN2 translational control module in adenocarcinoma of pancreas, BP.DD
Abstract
Pancreatic adenocarcinoma is one of the most deadly cancers in the world although the incidence is not as high as other types of solid tumors. In Brazil, it accounts for 2% of all cancers and 4% of deaths from this disease. The main cause of so many deaths is the difficulty of an early and accurate diagnosis, causing the cancer to be discovered already in advanced stages. As therapy, in...
- Expression of RNA modifying enzymes in Clear Cell Renal Cell Carcinoma and Breast Adenocarcinoma, BP.DD
Abstract
Covalent post-transcriptional chemical modifications can occur in the molecules of RNA and do not alter its sequence. RNA modifications were already identified in ribosomal, transporters and messengers RNAs. The first identified mRNA modification was N6-methyladenosine (m6A), affecting almost all stages of RNA metabolism, from nucleus processing to cytoplasm translation and decay, there...
- Expression of RNA modifying enzymes in clear cell renal cell carcinoma and breast adenocarcinoma, BP.MS
Abstract
Epigenetic modifications are covalent chemical alterations that may occur in DNA or RNA molecules, but without sequence alteration. Currently, it has been known the modifications of ribosomal, transporter, and messenger RNAs. The first acknowledged mRNA modification was the N6-metiladenosine (m6A) it being followed afterwards by the discovering of pseudouridine (¨), 5-metilcitidine (5m...
- The role of IMPACT/GCN1/GCN2 translational control module in adenocarcinoma of pancreas, BP.MS
Abstract
Pancreatic adenocarcinoma is one of the most deadly cancers in the world although theincidence is not as high as other types of solid tumors. In Brazil, it accounts for 2% of all cancers and 4% of deaths from this disease. The main cause of so many deaths is the difficulty of an early and accurate diagnosis, causing the cancer to be discovered already in advanced stages. As therapy, in ...
- Identification of molecular alterations in breast tumors: a translational approach, BP.DD
Abstract
Breast cancer is the most prevalent tumor type among females and has a unique complexity, with considerable heterogeneity. Breast tumors can be classified into molecular subgroups to better target the therapeutic choice. However, even among patients of the same group there is a wide range of prognostic and therapeutic behavior, demonstrating a real need to identify more precise biomarke...
(Only some records are available in English at this moment)
- Isolation of total and polysomal mRNA from breast tumor and normal samples followed by libraries construcion for RNA sequencing, BE.EP.DD
Abstract
Breast cancer is the most prevalent type among the female sex and has a unique complexity, with considerable heterogeneity. Breast tumors are classified into molecular subgroups for the better targeting of the therapeutic choice. However, even among patients of the same group there is a wide range of prognostic and therapeutic behavior, demonstrating a real need to identify more precise...
| 1 / 1 | Ongoing research grants |
| 7 / 5 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 12 / 8 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 23 / 17 | All research grants and scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 13 |
| Citations | 189 |
| Cit./Article | 14.5 |
| Data from Web of Science | |
OSTAPCHENKO, VALERIY G.; BERALDO, FLAVIO H.; MOHAMMAD, AMRO H.; XIE, YU-FENG; HIRATA, PEDRO H. F.; MAGALHAES, ANA C.; LAMOUR, GUILLAUME; LI, HONGBIN; MACIEJEWSKI, ANDRZEJ; BELROSE, JILLIAN C.; et al. The Prion Protein Ligand, Stress-Inducible Phosphoprotein 1, Regulates Amyloid-beta Oligomer Toxicity. JOURNAL OF NEUROSCIENCE, v. 33, n. 42, p. 16552-16564, OCT 16 2013. Web of Science Citations: 36. (09/14027-2, 12/04370-4)
BERTONHA, FERNANDA BERNARDI; BARROS FILHO, MATEUS DE CAMARGO; KUASNE, HELLEN; DOS REIS, PATRICIA PINTOR; PRANDO, ERIKA DA COSTA; AUGUSTO MOYANO MUNOZ, JUAN JOSE; ROFFE, MARTIN; MAROSO HAJJ, GLAUCIA NOELI; KOWALSKI, LUIZ PAULO; RAINHO, CLAUDIA APARECIDA; et al. PHF21B as a candidate tumor suppressor gene in head and neck squamous cell carcinomas. MOLECULAR ONCOLOGY, v. 9, n. 2, p. 450-462, FEB 2015. Web of Science Citations: 5. (08/57887-9, 12/04370-4)
ALVARENGA, ARTHUR W.; COUTINHO-CAMILLO, CLAUDIA M.; RODRIGUES, BRUNA R.; ROCHA, RAFAEL M.; TORRES, LUIZ FERNANDO B.; MARTINS, VILMA R.; DA CUNHA, ISABELA W.; HAJJ, GLAUCIA N. M.. A Comparison between Manual and Automated Evaluations of Tissue Microarray Patterns of Protein Expression. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, v. 61, n. 4, p. 272-282, APR 2013. Web of Science Citations: 18. (09/14027-2, 12/04370-4)
CAETANO, FABIANA A.; BERALDO, FLAVIO H.; HAJJ, GLAUCIA N. M.; GUIMARAES, ANDRE L.; JUERGENSEN, SOFIA; WASILEWSKA-SAMPAIO, ANA PAULA; HIRATA, PEDRO H. F.; SOUZA, IVANA; MACHADO, CLEITON F.; WONG, DAISY Y. -L.; et al. Amyloid-beta oligomers increase the localization of prion protein at the cell surface. Journal of Neurochemistry, v. 117, n. 3, p. 538-553, MAY 2011. Web of Science Citations: 52. (09/14027-2, 08/00390-5)
HAJJ, GLAUCIA N. M.; DA SILVA, FERNANDA F.; DE BELLIS, BARBARA; LUPINACCI, FERNANDA C. S.; BELLATO, HERMANO M.; CRUZ, JUVANIER R.; SEGUNDO, CLAUDIONOR N. C.; FAQUINI, V, IGOR; TORRES, LEURIDAN C.; SANEMATSU, I, PAULO; et al. Aberrant expression of RSK1 characterizes high-grade gliomas with immune infiltration. MOLECULAR ONCOLOGY, v. 14, n. 1, p. 159-179, JAN 2020. Web of Science Citations: 0. (15/15451-3, 18/17796-6)
SULLA LUPINACCI, FERNANDA CRISTINA; KUASNE, HELLEN; ROFFE, MARTIN; VASSALAKIS, JULIA AVIAN; DA SILVA, FERNANDA FERREIRA; SANTOS, TIAGO GOSS; ANDRADE, VICTOR PIANA; SANEMATSU, PAULO; MARTINS, VILMA REGINA; ROGATTO, SILVIA REGINA; et al. Polysome Profiling of a Human Glioblastoma Reveals Intratumoral Heterogeneity. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 20, n. 9, MAY 1 2019. Web of Science Citations: 0. (15/15451-3, 18/17796-6)
LIANG, SHUO; BELLATO, HERMANO MARTINS; LORENT, JULIE; LUPINACCI, FERNANDA C. S.; OERTLIN, CHRISTIAN; VAN HOEF, VINCENT; ANDRADE, VICTOR P.; ROFFE, MARTIN; MASVIDAL, LAIA; HAJJ, GLAUCIA N. M.; et al. Polysome-profiling in small tissue samples. Nucleic Acids Research, v. 46, n. 1, JAN 9 2018. Web of Science Citations: 5. (13/03315-2, 15/15451-3, 14/15550-9, 14/04513-5)
MACHADO, LUIS EDUARDO; ALVARENGA, ARTHUR WILLIAM; DA SILVA, FERNANDA FERREIRA; ROFFE, MARTIN; BEGNAMI, MARIA DIRLEI; BLEGGI TORRES, LUIS FERNANDO; DA CUNHA, ISABELA WERNECK; MARTINS, VILMA REGINA; MAROSO HAJJ, GLAUCIA NOELI. Overexpression of mTOR and p(240-244)S6 in IDH1 Wild-Type Human Glioblastomas Is Predictive of Low Survival. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, v. 66, n. 6, p. 403-414, JUN 2018. Web of Science Citations: 4. (15/15451-3, 14/15550-9)
ALVARENGA, ARTHUR WILLIAM; MACHADO, LUIS EDUARDO; RODRIGUES, BRUNA ROZ; SULLA LUPINACCI, FERNANDA CRISTINA; SANEMASTU, PAULO; MATTA, EDUARDO; ROFFE, MARTIN; BLEGGI TORRES, LUIS FERNANDO; DA CUNHA, ISABELA WERNECK; MARTINS, VILMA REGINA; et al. Evaluation of Akt and RICTOR Expression Levels in Astrocytomas of All Grades. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, v. 65, n. 2, p. 93-103, FEB 2017. Web of Science Citations: 9. (09/14027-2, 14/15550-9)
BELLATO, HERMANO MARTINS; MAROSO HAJJ, GLAUCIA NOELI. Translational control by eIF2 alpha in neurons: Beyond the stress response. CYTOSKELETON, v. 73, n. 10, p. 551-565, OCT 2016. Web of Science Citations: 11. (14/15550-9, 14/04513-5)
SANTOS, TIAGO GOSS; MARTINS, VILMA REGINA; MAROSO HAJJ, GLAUCIA NOELI. Unconventional Secretion of Heat Shock Proteins in Cancer. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 18, n. 5, MAY 2017. Web of Science Citations: 18. (15/02098-3, 09/14027-2, 14/15550-9)
HAJJ, GLAUCIA N. M.; ARANTES, CAMILA P.; SALLES DIAS, MARCOS VINICIOS; ROFFE, MARTIN; COSTA-SILVA, BRUNO; LOPES, MARILENE H.; PORTO-CARREIRO, ISABEL; RABACHINI, TATIANA; LIMA, FLAVIA R.; BERALDO, FLAVIO H.; et al. The unconventional secretion of stress-inducible protein 1 by a heterogeneous population of extracellular vesicles. CELLULAR AND MOLECULAR LIFE SCIENCES, v. 70, n. 17, p. 3211-3227, SEP 2013. Web of Science Citations: 21. (09/14027-2, 12/04370-4)
ROFFE, MARTIN; LUPINACCI, FERNANCLA C.; SOARES, LUANA C.; HAJJ, GLAUCIA N.; MARTINS, VILMA R.. Two widely used RSK inhibitors, BI-D1870 and SL0101, alter mTORC1 signaling in a RSK-independent manner. CELLULAR SIGNALLING, v. 27, n. 8, p. 1630-1642, AUG 2015. Web of Science Citations: 10. (13/25025-6, 13/03315-2, 09/14027-2, 11/21350-4, 12/04370-4)