bachelor's at Ciências Biológicas from Universidade de São Paulo (2000), bachelor's at Licenciatura en Ciencias Biológicas from Universidade de São Paulo (2004) and doctorate at Biochemistry from Universidade de São Paulo (2004). Has experience in Biochemistry, focusing on Molecular Biology, acting on the following subjects: prpc, vitronectina, sti1, acth and neuroproteção. (Source: Lattes Curriculum)
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Glioblastoma (GBM) is the most malignant and deadly brain tumor. Even with standard treatment, virtually all GBMs recur in months. High-throughput studies of GBMs resulted in several molecular classifications based on mRNA levels (transcriptome), however, they have not been useful in the clinic. One possible factor is that the final functional product of most genes is a protein. Our labor…
Cellular processes such as proliferation and differentiation depend on the correct control of mRNA translation. It is well known that the translation of mRNAs that promote tumor growth is favored by the alteration of signaling pathways that regulate the process of protein synthesis. Thus, translational control in tumors is especially important for regulating gene expression at the level o…
Cellular processes such as proliferation and differentiation are dependent on the correct control of mRNA translation. It is well known that the translation of mRNAs that promote tumor growth is favored by alterations in signaling pathways that regulate the process of protein synthesis. Thus, translational control in tumors is especially important for regulating gene expression at the lev…
(Only some records are available in English at this moment)
Pancreatic Adenocarcinoma is one of the most deadly Cancers in the world although the incidence is not as high as other types of solid tumors. In Brazil, it accounts for 2% of all Cancers and 4% of deaths from this disease. The main cause of so many deaths is the difficulty of an early and accurate diagnosis, causing the Cancer to be discovered already in advanced stages. As therapy, in a…
Covalent post-transcriptional chemical modifications can occur in the molecules of RNA and do not alter its sequence. RNA modifications were already identified in ribosomal, transporters and messengers RNAs. The first identified mRNA modification was N6-methyladenosine (m6A), affecting almost all stages of RNA metabolism, from nucleus processing to cytoplasm translation and decay, thereby…
Epigenetic modifications are covalent chemical alterations that may occur in DNA or RNA molecules, but without sequence alteration. Currently, it has been known the modifications of ribosomal, transporter, and messenger RNAs. The first acknowledged mRNA modification was the N6-metiladenosine (m6A) it being followed afterwards by the discovering of pseudouridine (¨), 5-metilcitidine (5mC)…
(Only some records are available in English at this moment)
Breast cancer is the most prevalent type among the female sex and has a unique complexity, with considerable heterogeneity. Breast tumors are classified into molecular subgroups for the better targeting of the therapeutic choice. However, even among patients of the same group there is a wide range of prognostic and therapeutic behavior, demonstrating a real need to identify more precise b…
| 1 / 1 | Ongoing research grants |
| 8 / 6 | Completed research grants |
| 14 / 10 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 24 / 18 | All research grants and scholarships |
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CV Lattes
ORCID