Danielle Palma de Oliveira
CV Lattes
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Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP) (Institutional affiliation for the last research proposal) Birthplace: Brazil
Graduate in Biochemical Pharmacy by Federal University of Alfenas (1999), Master's Degree in Toxicology and Toxicology Analysis from the University of São Paulo (2002) and a Ph.D. in Toxicology and Toxicology Analysis from the University of São Paulo (2005). Currently holds the position of Associate Professor of the Department of Clinical, Toxicological and Bromatological Analysis of the FACULTY OF PHARMACEUTICAL SCIENCES OF RIBEIRÃO PRETO (FCFRP / USP), in the area of ​​Environmental Toxicology, working in the Graduate and Postgraduate courses. She is member of Nominating Committee of the International Union of Toxicology (IUTOX) and past President of the Brazilian Society of Toxicology (2016-2017). She experience in the field of Pharmacy, with emphasis in Environmental and Occupational Toxicology, working mainly on the following topics: evaluation of the mutagenic activity of environmental samples, evaluation of genotoxic dyes and chlorination products, research of emerging environmental contaminants and alternative methods to animal experimentation. Currently, she is coordinator of the Graduate Program in Toxicology of FCFRP / USP. (Source: Lattes Curriculum)
- Use of multi-biomarker strategy in zebrafish as a platform to estimate NEUROCOMPORTAMENTAL effects induced by flame retardants, AP.R
Abstract
Flame retardants have effectively reduced the deaths and injuries caused by fires, and thus the need for their use in various consumer goods is indisputable. Among these compounds, polybrominated biphenyls (PBDEs) congeners are very efficient in mitigating the combustion process, reducing the spread of flames, besides being low cost. However, several studies have demonstrated the abilit...
- INCT 2014: National Institute for Alternative Technologies of Detection, Toxicological Evaluation and Removal of Micropollutants and Radioactivies, AP.TEM
Abstract
INCT-DATREM aims research groups national network formation active on the development of innovative technologies for micropollutants evaluation in chemical, toxicological and radioactive standards, as well as the investigation of more efficient technologies for residue, wastewater, effluent and water catchment treatment contributing to risk assessment, environmental conservation, human ...
- High-throughput screening analysis for toxicity assessment on neurobehavioral and development damage induced on zebrafish embryos exposed to emerging contaminants, AP.R
Abstract
The presence of emerging contaminants in water bodies has been attracting the attention of international scientific community, mainly due to the lack of toxicological data available considering exposure to low doses. In this context, investigation of minor effects using early life stages of development in Zebrafish, specially High-throughput screening analysis have received special int...
- Assessment of lethal, sublethal, teratogenic and genotoxic effects of textile dyes in zebrafish (Danio rerio) early developmental stages, AP.R
Abstract
The dyeing of fabrics began thousands of years ago and the commercial availability of dyes is enormous and growing. The Brazilian textile industry plays a very important role among the main economic activities of the country. However, the inefficiency in dyeing process, mainly during the dye fixation step, results in the loss of large quantities of colourants (2-50%) that reach the effl...
- Risk of exposure to various classes of polybrominated diphenyl ethers(PBDEs) congeners: mutagenic and genotoxic effects, AP.R
Abstract
The flame retardants are a group of substances with different chemical structures, widely used in various consumer goods. This intense use is explained by the fact that products made from wood, paper, plastic, among others, can burn very easily and quickly, reducing the chances of escape in case of fire. Thus, flame retardants are employed to delay or prevent the ignition and combustion...
(Only some records are available in English at this moment)
- Comparative toxicity analysis of trifluralin and tebuthiuron herbicides and its commercial formulations: effects on embryo-larval developmental of Zebrafish (Danio rerio), BP.DR
Abstract
Trifluralin (TFL) and Tebuthiuron (TBR) herbicides occurrence in environment have been reported by several studies. However, data on its toxicity in non-target organisms are not well stablished and may be associated with its commercial formulations. Since previous results from our research group has demonstrated TFL toxicity potential only at high concentrations, this research project a...
- Evaluation of the efficiency of treatment by advanced oxidation processes (AOP) in the removal/reduction of toxicity induced in aquatic organisms by wastewater produced by petroleum industries, BP.MS
Abstract
Petroleum oily sludge is a residue produced by the oil industry that is also known as produced water and residual water from petroleum. Being ditched in aquatic environments, this contaminant can affect their biota and may lead to irreversible damages to the impaired ecosystems. Produced water toxicity is due to its diverse composition, such as heavy metals, organic and inorganic compo...
- Local toxic effects evaluation in epidermis due dyes exposure used in hair dyes, BP.DD
Abstract
Too much used animals in research starting about 3R's Concept what means Reduction, Refinement and Replacement, carrying the trend for global acceptance and many laboratories creation. About the Brazil, alternative methods proposed from European Union occurred in 2014 with seventeen methods recognized. The cosmetic industries have using some methods in 3D cultures due similarity to huma...
- Zebrafish as a model to predict effects of multiple environmental stressors: using a multi-biomarker approach, BP.PD
Abstract
Despite the advances in researches on chemicals toxicity, the large amount of multiple stressors into the environmental demands the development of efficient approaches to characterize the toxicological profile of a broad spectrum of chemical classes, regardless of their mechanism of action. The main goal of the present work is to tackle this gap and develop a battery of infraindividual ...
- Evaluation of the deleterious effects of psychotropic drugs to zebrafish embryo-larval development, BP.MS
Abstract
In the last years, the prescription and use of psychotropic drugs have being increasing around the world, consequently the discharge of these drugs and their metabolites have also increased in wastewater. Considering the presence in the environment and the toxic effects to target and non target species, these compounds were classified as emerging water contaminants. The main sources of ...
- Evaluation of the mutagenic potential of textile dyes using the micronucleus assay, BP.MS
Abstract
Dyes and pigments are important compounds for many types of industries, being used in medicines, cosmetics, food, clothing, plastics, rubber, among others. Currently, around 7 x 105 tons of these compounds are produced all over the world per year, and approximately 26,500 tons / year are consumed in Brazil. The production of dyes, despite great economic importance is the target of envir...
(Only some records are available in English at this moment)
- Neurodegenerative zebrafish models and setting up new efficacy assays, BE.EP.PD
Abstract
Despite the advances in chemicals toxicity research, there is a lack of more efficient and informative toxicity approaches to evaluate the large number of existing chemicals. A major challenge is characterizing the neurotoxic potential of chemicals, which have scarce hazard data available. Thus, efforts to assess the neurotoxic potential of chemicals are needed. Our main goal is to tack...
- Ecotoxicological evaluation of the efficiency of the treatment of petroleum produced water in aquatic organisms (Dugesia tigrina e Chironomus riparius), BE.EP.MS
Abstract
Oil is one of the most important products for modern society as it is the main source of energy for various industrial sectors. In this way, it has high commercial value and, consequently, high extraction rates. During its productive process, the petroleum industry generates different types of waste. Among them, there is the petroleum produced water, also known as produced water or only...
- Toxicogenomic and biochemical approaches to toxicity assessment of natural and synthetic dyes to zebrafish, BE.EP.DR
Abstract
Organic compounds present in natural resources have been used in several experimental conditions aimed to develop safe human health dyes as alternative to dyeing industries, replacing synthetic dyes, since these are precursors of mutagenic compounds. Moreover, the use of natural dyes can add value to the final product. Many phenolic compounds extracted from microorganisms are potential ...
- In vitro studies of the potencial of oxidative stress and immunotoxic potencial of basic red 51 and basic yellow 57 in keratinocytes, BE.EP.DR
Abstract
Nowdays,the use of sinthetic hair dyes has increased. Many of these dyes belong to the class of azo dyes (-N=N-). It is known that aromatic amines can be generated after the breakage of the azo group leading to toxic compounds that may be harmfull to human beings and animals.According to the literature, some aromatic amines can be absorbed by the skin leading to mutagenic, carcinogenici...
| 2 / 2 | Ongoing research grants |
| 7 / 6 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 11 / 10 | Completed scholarships in Brazil |
| 1 / 1 | Ongoing scholarships abroad |
| 3 / 3 | Completed scholarships abroad |
| 27 / 25 | All research grants and scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 16 |
| Citations | 194 |
| Cit./Article | 12.1 |
| Data from Web of Science | |
DRUMOND CHEQUER, FARAH MARIA; LIZIER, THIAGO MESCOLOTO; DE FELICIO, RAFAEL; BOLDRIN ZANONI, MARIA VALNICE; DEBONSI, HOSANA MARIA; LOPES, NORBERTO PEPORINE; DE OLIVEIRA, DANIELLE PALMA. The azo dye Disperse Red 13 and its oxidation and reduction products showed mutagenic potential. TOXICOLOGY IN VITRO, v. 29, n. 7, p. 1906-1915, OCT 2015. Web of Science Citations: 19. (10/17178-9, 06/02505-9)
LEME, DANIELA MORAIS; RODRIGUES DE OLIVEIRA, GISELE AUGUSTO; MEIRELES, GABRIELA; DOS SANTOS, TUANE CRISTINA; BOLDRIN ZANONI, MARIA VALNICE; DE OLIVEIRA, DANIELLE PALMA. Genotoxicological assessment of two reactive dyes extracted from cotton fibres using artificial sweat. TOXICOLOGY IN VITRO, v. 28, n. 1, SI, p. 31-38, FEB 2014. Web of Science Citations: 22. (10/14941-3)
ZANONI, THALITA B.; TIAGO, MANOELA; FAIAO-FLORES, FERNANDA; DE MORAES BARROS, SILVIA B.; BAST, AALT; HAGEMAN, GEJA; DE OLIVEIRA, DANIELLE PALMA; MARIA-ENGLER, SILVYA S.. Basic Red 51, a permitted semi-permanent hair dye, is cytotoxic to human skin cells: Studies in monolayer and 3D skin model using human keratinocytes (HaCaT). Toxicology Letters, v. 227, n. 2, p. 139-149, JUN 5 2014. Web of Science Citations: 15. (10/07116-6, 11/07441-7)
LEME, DANIELA MORAIS; PRIMO, FERNANDO LUCAS; GOBO, GRACIELY GOMIDES; VIEIRA DA COSTA, CLEBER RAFAEL; TEDESCO, ANTONIO CLAUDIO; DE OLIVEIRA, DANIELLE PALMA. Genotoxicity Assessment of Reactive and Disperse Textile Dyes Using Human Dermal Equivalent (3D Cell Culture System). JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, v. 78, n. 7, p. 466-480, APR 3 2015. Web of Science Citations: 8. (10/14941-3)
LEME, DANIELA MORAIS; RODRIGUES DE OLIVEIRA, GISELE AUGUSTO; MEIRELES, GABRIELA; BRITO, LARA BARROSO; RODRIGUES, LAIS DE BRITO; DE OLIVEIRA, DANIELLE PALMA. Eco- and Genotoxicological Assessments of Two Reactive Textile Dyes. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, v. 78, n. 5, p. 287-300, MAR 4 2015. Web of Science Citations: 20. (10/14941-3)
MEIRELES, GABRIELA; DAAM, MICHIEL A.; MADEIRA SANCHES, ANA LETICIA; ZANONI, MARIA V. B.; SOARES, AMADEU M. V. M.; GRAVATO, CARLOS; DE OLIVEIRA, DANIELLE P.. Red disperse dyes (DR 60, DR 73 and DR 78) at environmentally realistic concentrations impact biochemical profile of early life stages of zebrafish (Danio rerio). Chemico-Biological Interactions, v. 292, p. 94-100, AUG 25 2018. Web of Science Citations: 2. (16/03281-9, 17/05543-3, 14/14621-0)
ABE, FLAVIA R.; MENDONCA, JACQUELINE N.; MORAES, LUIZ A. B.; DE OLIVEIRA, GISELE A. R.; GRAVATO, CARLOS; SOARES, AMADEU M. V. M.; DE OLIVEIRA, DANIELLE P.. Toxicological and behavioral responses as a tool to assess the effects of natural and synthetic dyes on zebrafish early life. Chemosphere, v. 178, p. 282-290, JUL 2017. Web of Science Citations: 15. (13/14397-0, 14/27009-0)
RODRIGUES DE OLIVEIRA, GISELE AUGUSTO; MORAIS LEME, DANIELA; DE LAPUENTE, JOAQUIN; BRITO, LARA BARROSO; PORREDON, CONSTANCA; RODRIGUES, LAIS DE BRITO; BRULL, NATALIA; SERRET, JOAN TXU; BORRAS, MIQUEL; DISNER, GEONILDO RODRIGO; et al. A test battery for assessing the ecotoxic effects of textile dyes. Chemico-Biological Interactions, v. 291, p. 171-179, AUG 1 2018. Web of Science Citations: 12. (10/01487-2)
ABE, FLAVIA R.; SOARES, AMADEU M. V. M.; DE OLIVEIRA, DANIELLE P.; GRAVATO, CARLOS. Toxicity of dyes to zebrafish at the biochemical level: Cellular energy allocation and neurotoxicity. Environmental Pollution, v. 235, p. 255-262, APR 2018. Web of Science Citations: 12. (13/14397-0, 13/01509-4, 14/27009-0)
VALIM BRIGANTE, TAMIRES AMABILE; ABE, FLAVIA R.; ZUARDI, ANTONIO WALDO; CECILIO HALLAK, JAIME EDUARDO; CRIPPA, JOSE ALEXANDRE S.; DE OLIVEIRA, DANIELLE P.. Cannabidiol did not induce teratogenicity or neurotoxicity in exposed zebrafish embryos. Chemico-Biological Interactions, v. 291, p. 81-86, AUG 1 2018. Web of Science Citations: 7. (14/50891-1, 16/03281-9)
ABE, FLAVIA R.; GRAVATO, CARLOS; SOARES, AMADEU M. V. M.; DE OLIVEIRA, DANIELLE P.. Biochemical approaches to assess oxidative stress induced by exposure to natural and synthetic dyes in early life stages in zebrafish. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, v. 80, n. 23-24, p. 1259-1268, 2017. Web of Science Citations: 8. (13/14397-0, 13/01509-4, 14/27009-0)
ROCHA, OTAVIO PELEGRINO; DE OLIVEIRA, DANIELLE PALMA. Investigation of a Brazilian tannery effluent by means of zebra fish (Danio rerio) embryo acute toxicity (FET) test. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, v. 80, n. 19-21, SI, p. 1078-1085, 2017. Web of Science Citations: 7. (08/10449-7, 13/09317-7)
ROCHA, OTAVIO PELEGRINO; CESILA, CIBELE APARECIDA; CHRISTOVAM, ELISA MARIA; DE MORAES BARROS, SILVIA BERLANGA; BOLDRIN ZANONI, MARIA VALNICE; DE OLIVEIRA, DANIELLE PALMA. Ecotoxicological risk assessment of the ``Acid Black 210{''} dye. Toxicology, v. 376, n. SI, p. 113-119, FEB 1 2017. Web of Science Citations: 14. (13/06172-8, 08/10449-7, 13/24340-5, 13/09317-7)
ZANONI, THALITA B.; HUDARI, FELIPE; MUNNIA, ARMELLE; PELUSO, MARCO; GODSCHALK, ROGER W.; ZANONI, MARIA VALNICE B.; DEN HARTOG, GERTJAN J. M.; BAST, AALT; BARROS, SILVIA B. M.; MARIA-ENGLER, SILVYA S.; et al. The oxidation of p-phenylenediamine, an ingredient used for permanent hair dyeing purposes, leads to the formation of hydroxyl radicals: Oxidative stress and DNA damage in human immortalized keratinocytes. Toxicology Letters, v. 239, n. 3, p. 194-204, DEC 15 2015. Web of Science Citations: 13. (10/07116-6, 08/10449-7, 12/05961-6)
RODRIGUES DE OLIVEIRA, GISELE AUGUSTO; DE LAPUENTE, JOAQUIN; TEIXIDO, ELISABET; PORREDON, CONSTANCA; BORRAS, MIQUEL; DE OLIVEIRA, DANIELLE PALMA. Textile dyes induce toxicity on zebrafish early life stages. Environmental Toxicology and Chemistry, v. 35, n. 2, p. 429-434, FEB 2016. Web of Science Citations: 20. (13/01509-4, 13/01735-4)
ABE, FLAVIA R.; MACHADO, ANA L.; SOARES, AMADEU M. V. M.; DE OLIVEIRA, DANIELLE P.; PESTANA, JOAO L. T.. Life history and behavior effects of synthetic and natural dyes on Daphnia magna. Chemosphere, v. 236, DEC 2019. Web of Science Citations: 0. (13/14397-0, 13/01509-4, 14/27009-0)
(References retrieved automatically from State of São Paulo Research Institutions)
ZANONI, Thalita Boldrin. Avaliação do perfil de citotoxicidade, mutagenicidade e genotoxicidade dos corantes Basic Red 51, Basic Yellow 57 e P-Fenilenodiamina usados na tintura de cabelo em células da pele. 2014. Tese (Doutorado) – Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto.
CESILA, Cibele Aparecida. Avaliação do potencial mutagênico de corantes têxteis por meio do ensaio de micronúcleo. 2015. Dissertação (Mestrado) - Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto.
ABE, Flavia Renata. Avaliação ecogenotoxicológica de corante natural extraído de micro-organismo. 2017. Tese (Doutorado) – Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto.
MEIRELES, Gabriela. Avaliação eco/genotoxicológica dos corantes têxteis Reactive Blue 4 e Reactive Blue 15. 2013. Dissertação (Mestrado) - Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto.
OLIVEIRA, Gisele Augusto Rodrigues de. Avaliação toxicogenética e ecotoxicológica de corantes têxteis. 2013. Tese (Doutorado) – Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto.
ROCHA, Otávio Pelegrino. Avaliação do risco ecogenotoxicológico da utilização de corantes têxteis. 2016. Tese (Doutorado) – Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto.
PRADO, Maíra Rocha de Souza. Avaliação dos efeitos deletérios de fármacos psicotrópicos sobre o desenvolvimento dos estágios embrio-larvais de zebrafish. 2018. Dissertação (Mestrado) - Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto.