Full Professor at the Ribeirão Preto Medical School, University of São Paulo (FMRP/USP). Participated in a Pre-Scientific Initiation program at the University of Brasília during high school (1991-1993) and graduated in Biological Sciences from the University of Brasília (1994-1997). Obtained a Ph.D. in Microbiology, Immunology, and Parasitology from the Paulista School of Medicine/Federal University of São Paulo (1998-2003), completed a Postdoctoral Fellowship in Microbial Pathogenicity at Yale University, USA (2003-2006), and earned the title of Associate Professor from the Ribeirão Preto Medical School/University of São Paulo (2011). Full member of the São Paulo State Academy of Sciences (ACIESP) and the Latin American Academy of Sciences (ACAL). CNPq Research Productivity Fellow, level 1B. Works in the fields of Immunology, Microbiology, Parasitology, and Cell Biology, with an emphasis on pathogen-host cell interaction and aspects of microbial pathogenicity and innate immunity. Published relevant articles that have significantly impacted the advancement of science. Mentored 21 master's students, 19 Ph.D. students, and dozens of undergraduate research students. Delivered over 180 scientific lectures, of which at least 40 were given abroad. Contributes significantly to the Brazilian scientific and educational system, collaborating with universities, scientific societies, and FAPESP, where a member of the scientific board since 2016, currently serving as the manager of the Biomedical Sciences area. (Source: Lattes Curriculum)
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Leishmaniasis are a group of diseases to pose a major public health problem worldwide, affecting mainly less favored individuals from emerging countries. The diseases are caused by protozoan parasites of the Leishmania spp genus, presenting different known clinical forms: cutaneous, mucocutaneous and visceral. In the mammalian host these parasites preferentially infect phagocytic cells, p…
Differential recognition of pathogenic versus non-pathogenic microbes is essential to ensure rapid and effective immune responses that limit the replication of pathogenic microbes in cells and tissues. This differential recognition occurs through receptors located in the cytoplasm of innate immune cells. Among these receptors is a family of cytoplasmic proteins that contain NBD and LRR do…
Equipment for the reading of immunological tests using chemiluminescence and immunofluorescence. It allows the acquisition of results of biological tests with greater accuracy and precision. (AU)
(Only some records are available in English at this moment)
COVID-19, caused by the new coronavirus (SARS-CoV-2) has become a worldwide health problem, with more than one million confirmed cases and 50,000 deaths by early April 2020. In its most severe forms, COVID-19 symptoms includes fever, cough, fatigue, headache and may progress to respiratory distress syndrome and death. The severe cases of COVID-19 are characterized by an intense inflammato…
Leishmaniasis is a devastating parasitic disease that targets the poorest of society and is the 9th largest global infectious disease burden (WHO). It is truly a Neglected Infectious Disease as the combined financial support of basic and clinical research equates to <2% of infectious disease R&D resources available. Consequently, there are no vaccines available currently and the limited a…
The SpectraMax i3 Platform support development of assays that measure absorbance, fluorescence, luminescence in real time. The equipment will be equipped with the SpectraMax Minimax, which allows the imaging of the cultures in real time. The equipment is multifunctional and support development of several assays, thus favoring several users of different laboratories. (AU)
(Only some records are available in English at this moment)
Coronavirus disease 2019 (COVID-19) is characterized by an exacerbated inflammatory response caused by the SARS-CoV-2 virus. The disease has affected millions of people around the world, causing a global public health crisis, with around 6.9 million deaths to date. Despite vaccination, outbreaks and isolated cases of COVID-19 continue to occur. In addition, only 17.4% of people in low-in…
Leishmaniasis is a neglected tropical disease that predominantly affects populations in tropical and subtropical regions of Africa, Asia, and Latin America, with approximately 12 million global cases and 1.5-2 million new cases annually. The infection can be caused by 20 species of pathogens, resulting in visceral or cutaneous forms of the disease, ranging from localized lesions to mucocu…
(Only some records are available in English at this moment)
Leishmaniasis are a set of diseases that cause a major public health problem around the world, affecting mainly less favored individuals from emerging countries. The diseases are caused by protozoan parasites of the genus Leishmania spp., presenting different known clinical forms: cutaneous, mucocutaneous and visceral. In the mammalian host, these parasites preferentially infect phagocyti…
(Only some records are available in English at this moment)
Coxiella burnetii is a Gram-negative bacterium and causative agent of Q fever in humans. The bacterium is highly adapted to infect alveolar macrophages and subvert their functions, including the avoidance of TLR recognition, the inhibition of apoptosis and the modulation of diverse vesicle traffic pathways. Its virulence is dependent on the translocation of bacterial proteins (called effe…
The innate immune system is composed of several sensors and effectors widely expressed in macrophages, dendritic cells and epithelial cells. These molecules can rapidly induce inflammatory responses by triggering the production of cytokines, chemokines and release of danger signals present in the cytoplasm. In this context, host cell death has been reemerged as an important effector mecha…
Autophagy is a process of cellular degradation that captures and degrades organelles and intracellular pathogens and delivers them to autolysosomes for destruction. The role of autophagy in Trypanosoma cruzi infection is still largely unknown. During the development of the Ph.D. project, we found that autophagy is induced in response to T. cruzi favoring restriction of parasite replicatio…
| 4 / 4 | Ongoing research grants |
| 9 / 7 | Completed research grants |
| 10 / 10 | Ongoing scholarships in Brazil |
| 75 / 51 | Completed scholarships in Brazil |
| 3 / 3 | Completed scholarships abroad |
| 101 / 75 | All research grants and scholarships |
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