CV Lattes
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Ministério da Educação (Brasil). Universidade Federal do ABC (UFABC). Centro de Ciências Naturais e Humanas (CCNH) (Institutional affiliation for the last research proposal) Birthplace: Brazil
bachelor's at Bacharelado em Química from Instituto de Química - Universidade de São Paulo (1997), bachelor's at Licenciatura em Química from Faculdade de Educação - Universidade de São Paulo (1999) and doctorate at Química from Instituto de Química - Universidade de São Paulo (2002). Has experience in Chemistry, focusing on Chemistry of the Natural Products (Source: Lattes Curriculum)
| News published in Agência FAPESP Newsletter about the researcher |
| Biocompound from Atlantic Rainforest combats leishmaniasis and Chagas disease |
| Compound isolated from plant in pepper family proves effective against parasites |
| Testing of a natural compound against leishmaniasis and Chagas disease |
| Plant from Brazil contains a compound with an anti-inflammatory action |
| Collaborative research augments therapy for visceral leishmaniasis |
| Articles published in other media outlets (1 total): |
| FarolCom: Composto natural é testado contra leishmaniose e doença de Chagas (26/May/2015) |
Natural products obtained from Brazilian flora constitute a powerful and diverse source of bioactive molecules, which are increasingly in high demand for the development of new human therapeutics. These bioactive molecules can be considered 'pre-optimized' by Nature to possess bioactivity and 'drug-like' properties. Affirmation of these statements is realized in the fact that more than 50…
In the present project will be selected plant species from Sao Paulo State biomes (Atlantic Forest and "Cerrado") aiming the structural characterization of natural products/semisynthetic derivatives with antiparasitic activity as well as evaluation of pre-clinical and toxicological potential, in continuation to the study begun in 2015 with FAPESP funding (project 2015/11936-2). Thus, diff…
In this project will be continued aiming the selection of plant species that occur in the remaining areas of the Atlantic Forest of São Paulo State, with the main purpose of conducting pharmacological studies, isolation and structural determination of active compounds, in addition to establishing relations structure/biologic activities obtained with compounds of vegetable matrices. This s…
(Only some records are available in English at this moment)
Plant species, as well as other natural products, have been used as therapeutics for treatment of several diseases since ancient times. There is great chemodiversity in plants, which make them important sources for new drug development studies, including for neglected diseases such as Chagas disease. Therefore, this project aims to conduct a molecular dereplication study of Porcelia macro…
Brazil has great biological diversity and can enjoy many species with unknown pharmacological properties. Phytochemical studies with different species of the genus Nectandra have shown great structural diversity of bioactive metabolites, however, there is no information in the literature related to the chemical composition and/or biological potential of the species Nectandra barbellata. B…
Microorganisms participate in biological processes as long before man discover the possibilities for its systematic use. The production of compounds with pharmacological importance from these microscopic beings is well studied since the discovery of Penicillin. Currently, genomic analyzes have provided numerous new Natural Products from microorganisms. Therefore, this work aims to analyzi…
Plants are used for medicinal purposes since ancient times. Natural compounds extracted from plants have been highlighted as important sources of new therapeutic agents, used in the treatment of several ills, especially neglected diseases, such as leishmaniosis, Chagas disease among others. In this aspect, several studies are directed to evaluation of biological activities of natural comp…
Malignant melanoma is a highly aggressive and lethal cancer resulted of mutations in the melanocytes, which in the later stages the current therapy is ineffective. Therefore, alternative therapies are required to induce the cytotoxic effects against tumor and at the same time do not damage the patient body. Plants produce and accumulate many compounds which have pharmacological effects, m…
(Only some records are available in English at this moment)
Brazilian Atlantic forest is one of most important regions worldwide, considered as a biodiversity hotspot due to its high degree of biodiversity (plant, animals and microorganisms). Based in this aspect, the investigation of metabolites from different plants species from this biome could be a source of new prototypesto therapeutic treatment for several diseases, including neglected tropi…
| 2 / 1 | Ongoing research grants |
| 8 / 6 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 10 / 5 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 23 / 15 | All research grants and scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 65 |
| Citations | 453 |
| Cit./Article | 7.0 |
| Data from Web of Science | |
PAROLIN, GIOVANA A.; GONCALVES, GIULIA E. G.; COSTA-SILVA, THAIS A.; TEMPONE, ANDRE G.; CASELI, LUCIANO; LAGO, JOAO HENRIQUE G.; PERES, LAURA O.. Evaluation of the effects in cellular membrane models of antitrypanosomal poly-thymolformaldehyde (PTF) using Langmuir monolayers. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, v. 1863, n. 2, FEB 1 2021. Web of Science Citations: 0. (18/18180-9, 18/22214-6, 18/10279-6, 19/03239-0, 18/07885-1, 14/50869-6)
FERREIRA, BRUNO ANTONIO; NORTON FILHO, ANDERSON FERRAZ; DECONTE, SIMONE RAMOS; TOMIOSSO, TATIANA CARLA; THEVENARD, FERNANDA; ANDRADE, SILVIA PASSOS; GHILARDI LAGO, JOAO HENRIQUE; ARAUJO, FERNANDA DE ASSIS. Sesquiterpene Polygodial from Drimys brasiliensis (Winteraceae) Down-Regulates Implant-Induced Inflammation and Fibrogenesis in Mice. Journal of Natural Products, v. 83, n. 12, p. 3698-3705, DEC 24 2020. Web of Science Citations: 0. (18/07885-1)
OLIVEIRA, EMERSON A.; BRITO, IVANILDO A.; LIMA, MARTA L.; ROMANELLI, MAIARA; MOREIRA-FILHO, JOSE T.; NEVES, BRUNO J.; ANDRADE, CAROLINA H.; SARTORELLI, PATRICIA; TEMPONE, ANDRE G.; COSTA-SILVA, THAIS A.; et al. Antitrypanosomal Activity of Acetogenins Isolated from the Seeds of Porcelia macrocarpa Is Associated with Alterations in Both Plasma Membrane Electric Potential and Mitochondrial Membrane Potential. Journal of Natural Products, v. 82, n. 5, p. 1177-1182, MAY 2019. Web of Science Citations: 0. (18/10279-6, 18/07885-1)
UENO, ANDERSON K.; BARCELLOS, ALINE F.; COSTA-SILVA, THAIS A.; MESQUITA, JULIANA T.; FERREIRA, DAIANE D.; TEMPONE, ANDRE G.; ROMOFF, PAULETE; ANTAR, GUILHERME M.; LAGO, JOAO HENRIQUE G.. Antitrypanosomal activity and evaluation of the mechanism of action of diterpenes from aerial parts of Baccharis retusa (Asteraceae). Fitoterapia, v. 125, p. 55-58, MAR 2018. Web of Science Citations: 7. (15/23403-9, 15/11936-2, 14/08961-2)
GONCALVES, GIULIA ELISA G.; MORAIS, THIAGO R.; LAGO, JOAO HENRIQUE G.; CASELI, LUCIANO. Incorporation of polygodial in Langmuir films of selected lipids. Thin Solid Films, v. 669, p. 19-28, JAN 1 2019. Web of Science Citations: 0. (15/23446-0, 18/07885-1)
DE SOUSA, FERNANDA S.; GRECCO, SIMONE S.; GIROLA, NATALIA; AZEVEDO, RICARDO A.; FIGUEIREDO, CARLOS R.; LAGO, JOAO HENRIQUE G.. Neolignans isolated from Nectandra leucantha induce apoptosis in melanoma cells by disturbance in mitochondrial integrity and redox homeostasis. Phytochemistry, v. 140, p. 108-117, AUG 2017. Web of Science Citations: 8. (15/11936-2, 15/04143-6)
GOMES, KAIO S.; DA COSTA-SILVA, THAIS A.; OLIVEIRA, IGOR H.; AGUILAR, ANDREA M.; OLIVEIRA-SILVA, DIOGO; UEMI, MIRIAM; SILVA, WENDER A.; MELO, LENNINE R.; ANDRADE, CARLOS KLEBER Z.; TEMPONE, ANDRE G.; et al. Structure-activity relationship study of antitrypanosomal chalcone derivatives using multivariate analysis. Bioorganic & Medicinal Chemistry Letters, v. 29, n. 12, p. 1459-1462, JUN 15 2019. Web of Science Citations: 0. (18/10279-6, 18/07885-1)
CONSERVA, GEANNE ALEXANDRA A.; GIROLA, NATALIA; FIGUEIREDO, CARLOS R.; AZEVEDO, RICARDO A.; MOUSDELL, SASHA; SARTORELLI, PATRICIA; SOARES, MARISI G.; ANTAR, GUILHERME M.; LAGO, JOAO HENRIQUE G.. Terpenoids from Leaves of Guarea macrophylla Display In Vitro Cytotoxic Activity and Induce Apoptosis In Melanoma Cells. Planta Medica, v. 83, n. 16, p. 1289-1296, NOV 2017. Web of Science Citations: 2. (14/08961-2)
GUIMARAES GONCALVES, GIULIA ELISA; MORAIS, THIAGO RAHAL; GOMES, KAIO DE SOUZA; COSTA-SILVA, THAIS ALVES; TEMPONE, ANDRE GUSTAVO; GHILARDI LAGO, JOAO HENRIQUE; CASELI, LUCIANO. Antitrypanosomal activity of epi-polygodial from Drimys brasiliensis and its effects in cellular membrane models at the air-water interface. BIOORGANIC CHEMISTRY, v. 84, p. 186-191, MAR 2019. Web of Science Citations: 0. (15/23446-0, 13/14262-7, 18/07885-1, 15/23403-9)
BARROSA, KAIDU H.; MECCHI, MURILO C.; RANDO, DANIELA G.; FERREIRA, ARI JOSE S.; SARTORELLI, PATRICIA; VALLE, MAIRA M. R.; BORDIN, SILVANA; CAPERUTO, LUCIANA C.; LAGO, JOAO HENRIQUE G.; LELLIS-SANTOS, CAMILO. Polygodial, a sesquiterpene isolated from Drimys brasiliensis (Winteraceae), triggers glucocorticoid-like effects on pancreatic beta-cells. Chemico-Biological Interactions, v. 258, p. 245-256, OCT 25 2016. Web of Science Citations: 2. (10/10778-0, 15/11936-2)
GRECCO, SIMONE S.; COSTA-SILVA, THAIS A.; JERZ, GEROLD; DE SOUSA, FERNANDA S.; ALVES CONSERVA, GEANNE A.; MESQUITA, JULIANA T.; GALUPPO, MARIANA K.; TEMPONE, ANDRE G.; NEVES, BRUNO J.; ANDRADE, CAROLINA H.; et al. Antitrypanosomal activity and evaluation of the mechanism of action of dehydrodieugenol isolated from Nectandra leucantha (Lauraceae) and its methylated derivative against Trypanosoma cruzi. Phytomedicine, v. 24, p. 62-67, JAN 15 2017. Web of Science Citations: 8. (15/11936-2, 13/07275-5)
DE ALMEIDA, BUANA C.; ARAUJO, BRUNO Q.; CARVALHO, ADONIAS A.; FREITAS, SAMYA DANIELLE L.; ALVES MACIEL, DAYANY DA S.; FERREIRA, ARI JOSE S.; TEMPONE, ANDRE G.; MARTINS, LIGIA F.; ALEXANDRE, TATIANA R.; CHAVES, MARIANA H.; et al. Antiprotozoal activity of extracts and isolated triterpenoids of `carnauba' (Copernicia prunifera) wax from Brazil. Pharmaceutical Biology, v. 54, n. 12, p. 3280-3284, DEC 2016. Web of Science Citations: 2. (15/11936-2)
BRITO, JULIANA R.; CAMILO, FERNANDA F.; FIGUEIREDO, CARLOS R.; AZEVEDO, RICARDO A.; ROMOFF, PAULETE; BUTURI, FATIMA O. S.; FAVERO, ORIANA A.; LAGO, JOAO HENRIQUE G.; FERREIRA, EDGARD A.. ISOLATION OF CYTOTOXIC NEOLIGNANS FROM Saururus cernuus L. (SAURURACEAE) USING IONIC LIQUID IN THE MICROWAVE ASSISTED EXTRACTION (MAE). Química Nova, v. 41, n. 7, p. 778-781, JUL 2018. Web of Science Citations: 1. (15/11936-2)
UMEHARA, ERIC; SILVA, THAIS A. COSTA; MENDES, VIVIANE M.; GUADAGNIN, RAFAEL C.; SARTORELLI, PATRICIA; TEMPONE, ANDRE G.; LAGO, JOAO HENRIQUE G.. Differential lethal action of C17:2 and C17:0 anacardic acid derivatives in Trypanosoma cruzi - A mechanistic study. BIOORGANIC CHEMISTRY, v. 102, SEP 2020. Web of Science Citations: 0. (18/10279-6, 18/07885-1)
YAMAMOTO, EDUARDO SEIJI; DE JESUS, JESSICA ADRIANA; BEZERRA-SOUZA, ADRIANA; BRITO, JULIANA R.; LAGO, JOAO HENRIQUE G.; LAURENTI, MARCIA DALASTRA; PASSERO, LUIZ FELIPE DOMINGUES. Tolnaftate inhibits ergosterol production and impacts cell viability of Leishmania sp.. BIOORGANIC CHEMISTRY, v. 102, SEP 2020. Web of Science Citations: 0. (15/17623-6, 18/07885-1, 16/00468-0)
MORAIS, THIAGO R.; COSTA-SILVA, THAIS A.; FERREIRA, DAIANE D.; NOVAIS, BIANCA J.; TORRECILHAS, ANA CLAUDIA T.; TEMPONE, ANDRE G.; LAGO, JOAO HENRIQUE G.. Antitrypanosomal activity and effect in plasma membrane permeability of (-)-bornyl p-coumarate isolated from Piper cernuum (Piperaceae). BIOORGANIC CHEMISTRY, v. 89, AUG 2019. Web of Science Citations: 1. (18/10279-6, 18/07885-1)
GRECCO, SIMONE DOS SANTOS; LETSYO, EMMANUEL; TEMPONE, ANDRE GUSTAVO; GHILARDI LAGO, JOAO HENRIQUE; JERZ, GEROLD. Electrospray mass-spectrometry guided target isolation of neolignans from Nectandra leucantha (Lauraceae) by high performance- and spiral-coil countercurrent chromatography. Journal of Chromatography A, v. 1608, DEC 20 2019. Web of Science Citations: 0. (18/07885-1, 18/09083-0)
MENGARDA, ANA C.; MENDONCA, POLIANA S.; MORAIS, CRISTIANE S.; COGO, RAMON M.; MAZLOUM, SUSANA F.; SALVADORI, MARIA C.; TEIXEIRA, FERNANDA S.; MORAIS, THIAGO R.; ANTAR, GUILHERME M.; LAGO, JOAO HENRIQUE G.; et al. Antiparasitic activity of piplartine (piperlongumine) in a mouse model of schistosomiasis. Acta Tropica, v. 205, MAY 2020. Web of Science Citations: 0. (18/07885-1, 16/22488-3)
UENO, ANDERSON K.; BARCELLOS, ALINE F.; GRECCO, SIMONE DOS S.; SARTORELLI, PATRICIA; GUADAGNIN, RAFAEL C.; ROMOFF, PAULETE; FERREIRA, MARCELO JOSE P.; TCACENCO, CELIZE M.; LAGO, JOAO HENRIQUE G.. Sesquiterpenes, diterpenes, alkenyl p-coumarates, and flavonoid from the aerial parts of Baccharis retusa (Asteraceae). Biochemical Systematics and Ecology, v. 78, p. 39-42, JUN 2018. Web of Science Citations: 1. (15/11936-2, 14/21593-2)
JESUS, JESSICA A.; FRAGOSO, THAIS N.; YAMAMOTO, EDUARDO S.; LAURENTI, MARCIA D.; SILVA, MARCELO S.; FERREIRA, AUREA F.; LAGO, JOAO HENRIQUE G.; GOMES, GABRIELA S.; PASSERO, LUIZ FELIPE D.. Therapeutic effect of ursolic acid in experimental visceral leishmaniasis. INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE, v. 7, n. 1, p. 1-11, APR 2017. Web of Science Citations: 15. (15/11936-2, 13/10133-8, 13/16297-2, 16/00468-0)
LONDERO, VINICIUS S.; COSTA-SILVA, THAIS A.; TEMPONE, ANDRE G.; NAMIYAMA, GISLENE M.; THEVENARD, FERNANDA; ANTAR, GUILHERME M.; BAITELLO, JOAO B.; LAGO, JOAO HENRIQUE G.. Anti-Trypanosoma cruzi activity of costic acid isolated from Nectandra barbellata (Lauraceae) is associated with alterations in plasma membrane electric and mitochondrial membrane potentials. BIOORGANIC CHEMISTRY, v. 95, JAN 2020. Web of Science Citations: 0. (18/10279-6, 17/17044-1, 18/07885-1)
DE SOUSA, FERNANDA S.; BALDIM, JOAO L.; AZEVEDO, RICARDO A.; FIGUEIREDO, CARLOS R.; PIEPER, PAULINE; SEAR, CLAIRE E.; ANDERSON, EDWARD A.; LAGO, JOAO HENRIQUE G.. Structure-activity relationship study of cytotoxic neolignan derivatives using multivariate analysis and computation-aided drug design. Bioorganic & Medicinal Chemistry Letters, v. 30, n. 16, AUG 15 2020. Web of Science Citations: 0. (15/11936-2, 15/04143-6, 16/19269-8, 18/07885-1)
GRECCO, SIMONE DOS S.; DORIGUETO, ANTONIO C.; LANDRE, IARA M.; SOARES, MARISI G.; MARTHO, KEVIN; LIMA, RICARDO; PASCON, RENATA C.; VALLIM, MARCELO A.; CAPELLO, TABATA M.; ROMOFF, PAULETE; et al. Structural Crystalline Characterization of Sakuranetin - An Antimicrobial Flavanone from Twigs of Baccharis retusa (Asteraceae). Molecules, v. 19, n. 6, p. 7528-7542, JUN 2014. Web of Science Citations: 4. (11/51739-0, 06/57626-5)
GREECO, SIMONE DOS S.; FELIX, MARIA JULIA P.; LAGO, JOAO HENRIQUE G.; PINTO, ERIKA G.; TEMPONE, ANDRE G.; ROMOFF, PAULETE; FERREIRA, MARCELO JOSE P.; SARTORELLI, PATRICIA. Anti-trypanosomal Phenolic Derivatives from Baccharis uncinella. NATURAL PRODUCT COMMUNICATIONS, v. 9, n. 2, p. 171-173, FEB 2014. Web of Science Citations: 11. (11/51739-0)
GIROLA, NATALIA; FIGUEIREDO, CARLOS R.; FARIAS, CAMYLA F.; AZEVEDO, RICARDO A.; FERREIRA, ADILSON K.; TEIXEIRA, SARAH F.; CAPELLO, TABATA M.; MARTINS, EUDER G. A.; MATSUO, ALISSON L.; TRAVASSOS, LUIZ R.; et al. Camphene isolated from essential oil of Piper cernuum (Piperaceae) induces intrinsic apoptosis in melanoma cells and displays antitumor activity in vivo. Biochemical and Biophysical Research Communications, v. 467, n. 4, p. 928-934, NOV 27 2015. Web of Science Citations: 17. (15/11936-2, 11/51739-0)
GRECCO, SIMONE DOS S.; REIMAO, JULIANA Q.; TEMPONE, ANDRE G.; SARTORELLI, PATRICIA; CUNHA, RODRIGO L. O. R.; ROMOFF, PAULETE; FERREIRA, MARCELO J. P.; FAVERO, ORIANA A.; LAGO, JOAO HENRIQUE G.. In vitro antileishmanial and antitrypanosomal activities of flavanones from Baccharis retusa DC. (Asteraceae). Experimental Parasitology, v. 130, n. 2, p. 141-145, FEB 2012. Web of Science Citations: 46. (08/11496-9, 06/57626-5)
DAL PICOLO, CAMILLA R.; BEZERRA, MARIANA P.; GOMES, KAIO S.; PASSERO, LUIZ FELIPE D.; LAURENTI, MARCIA D.; MARTINS, EUDER GLENDES A.; SARTORELLI, PATRICIA; LAGO, JOAO HENRIQUE G.. Antileishmanial activity evaluation of adunchalcone, a new prenylated dihydrochalcone from Piper aduncum L.. Fitoterapia, v. 97, p. 28-33, SEP 2014. Web of Science Citations: 17. (11/51739-0)
LAGO, JOAO HENRIQUE G.; TOLEDO-ARRUDA, ALESSANDRA C.; MERNAK, MARCIA; BARROSA, KAIDU H.; MARTINS, MILTON A.; TIBERIO, IOLANDA F. L. C.; PRADO, CARLA M.. Structure-Activity Association of Flavonoids in Lung Diseases. Molecules, v. 19, n. 3, p. 3570-3595, MAR 2014. Web of Science Citations: 42. (11/51739-0)
DA SILVA, ERICA BIOLCATI P.; SOARES, MARISI G.; MARIANE, BRUNA; VALLIM, MARCELO A.; PASCON, RENATA C.; SARTORELLI, PATRICIA; LAGO, JOAO HENRIQUE G.. The Seasonal Variation of the Chemical Composition of Essential Oils from Porcelia macrocarpa RE Fries (Annonaceae) and Their Antimicrobial Activity. Molecules, v. 18, n. 11, p. 13574-13587, NOV 2013. Web of Science Citations: 3. (11/51739-0)
BOU, DIEGO DINIS; LAGO, JOAO HENRIQUE G.; FIGUEIREDO, CARLOS R.; MATSUO, ALISSON L.; GUADAGNIN, RAFAEL C.; SOARES, MARISI G.; SARTORELLI, PATRICIA. Chemical Composition and Cytotoxicity Evaluation of Essential Oil from Leaves of Casearia Sylvestris, Its Main Compound alpha-Zingiberene and Derivatives. Molecules, v. 18, n. 8, p. 9477-9487, AUG 2013. Web of Science Citations: 28. (11/51739-0)
REA, ALEXANDRE; TEMPONE, ANDRE G.; PINTO, ERIKA G.; MESQUITA, JULIANA T.; RODRIGUES, ELIANA; SILVA, LUCIANA GRUS M.; SARTORELLI, PATRICIA; LAGO, JOAO HENRIQUE G.. Soulamarin Isolated from Calophyllum brasiliense (Clusiaceae) Induces Plasma Membrane Permeabilization of Trypanosoma cruzi and Mytochondrial Dysfunction. PLoS Neglected Tropical Diseases, v. 7, n. 12, DEC 2013. Web of Science Citations: 24. (11/51739-0)
BARBOSA, HENRIQUE; DA SILVA, RAFAEL LEONARDO C. G.; COSTA-SILVA, THAIS A.; TEMPONE, ANDRE G.; ANTAR, GUILHERME M.; LAGO, JOAO HENRIQUE G.; CASELI, LUCIANO. Interaction of dicentrinone, an antitrypanosomal aporphine alkaloid isolated from Ocotea puberula (Lauraceae), in cell membrane models at the air-water interface. BIOORGANIC CHEMISTRY, v. 101, AUG 2020. Web of Science Citations: 0. (19/03239-0, 18/00291-9, 18/10279-6, 18/07885-1)
JESUS, JESSICA ADRIANA; FRAGOSO DA SILVA, THAYS NICOLLI; YAMAMOTO, EDUARDO SEIJI; G. LAGO, JOAO HENRIQUE; DALASTRA LAURENTI, MARCIA; PASSERO, LUIZ FELIPE DOMINGUES. Ursolic Acid Potentializes Conventional Therapy in Experimental Leishmaniasis. PATHOGENS, v. 9, n. 10, OCT 2020. Web of Science Citations: 0. (18/24077-6, 18/07885-1, 16/00468-0, 16/10324-6)
PONCI, VITOR; SILVA, RAFAEL C.; SANTANA, FERNANDA PAULA R.; GRECCO, SIMONE S.; FORTUNATO, CELIA REGINA M.; OLIVEIRA, MARIA A.; TAVARES-DE-LIMA, WOTHAN; OLIVO, CLARICE R.; CALVO TIBERIO, IOLANDA DE FATIMA L.; GOMES, KAIO S.; et al. Biseugenol Exhibited Anti-Inflammatory and Anti-Asthmatic Effects in an Asthma Mouse Model of Mixed-Granulocytic Asthma. Molecules, v. 25, n. 22, NOV 2020. Web of Science Citations: 0. (18/06088-0, 18/07885-1)
SESSA, DEBORAH P.; MENGARDA, ANA C.; SIMPLICIO, PAULA E.; ANTAR, GUILHERME M.; LAGO, JOAO HENRIQUE G.; DE MORAES, JOSUE. 15 beta-Senecioyl-oxy-ent-kaur-16-en-19-oic Acid, a Diterpene Isolated from Baccharis lateralis, as Promising Oral Compound for the Treatment of Schistosomiasis. Journal of Natural Products, v. 83, n. 12, p. 3744-3750, DEC 24 2020. Web of Science Citations: 0. (16/22488-3, 18/07885-1)
IVANILDO A. BRITO; EMERSON A. OLIVEIRA; MARIANA H. CHAVES; FERNANDA THEVENARD; ANDRÉ F. RODRIGUES-OLIVEIRA; GUSTAVO BARBOSA-REIS; PATRICIA SARTORELLI; DIOGO OLIVEIRA-SILVA; ANDRE G. TEMPONE; THAIS A. COSTA-SILVA; et al. Antileishmanial Acetylene Fatty Acid and Acetogenins from Seeds of Porcelia macrocarpa. Journal of the Brazilian Chemical Society, v. 32, n. 2, p. 447-453, Fev. 2021. Web of Science Citations: 0. (18/10279-6, 18/07885-1)
MORAIS, THIAGO R.; ALVES CONSERVA, GEANNE A.; VARELA, MARINA T.; COSTA-SILVA, THAIS A.; THEVENARD, FERNANDA; PONCI, VITOR; FORTUNA, ANA; FALCAO, AMILCAR C.; TEMPONE, ANDRE G.; FERNANDES, JOAO PAULO S.; et al. Improving the drug-likeness of inspiring natural products - evaluation of the antiparasitic activity against Trypanosoma cruzi through semi-synthetic and simplified analogues of licarin A. SCIENTIFIC REPORTS, v. 10, n. 1, MAR 25 2020. Web of Science Citations: 2. (16/25028-3, 18/07885-1, 18/10279-6, 16/20633-6)
DE JESUS, JESSICA ADRIANA; LAURENTI, MARCIA DALASTRA; ANTONANGELO, LEILA; FARIA, CAROLINE SILVERIO; LAGO, JOAO HENRIQUE GHILARDI; PASSERO, LUIZ FELIPE DOMINGUES. Related Pentacyclic Triterpenes Have Immunomodulatory Activity in Chronic Experimental Visceral Leishmaniasis. JOURNAL OF IMMUNOLOGY RESEARCH, v. 2021, FEB 18 2021. Web of Science Citations: 0. (18/07885-1, 16/10324-6, 16/00468-0)
GRECCO, SIMONE DOS SANTOS; LETSYO, EMMANUEL; TEMPONE, ANDRE GUSTAVO; GHILARDI LAGO, JOAO HENRIQUE; JERZ, GEROLD. Electrospray mass-spectrometry guided target isolation of neolignans from Nectandra leucantha (Lauraceae) by high performance- and spiral-coil countercurrent chromatography. Journal of Chromatography A, v. 1608, DEC 20 2019. Web of Science Citations: 0. (18/07885-1, 18/09083-0)
BARBOSA, HENRIQUE; COSTA-SILVA, THAIS A.; ALVES CONSERVA, GEANNE A.; ARAUJO, ADELSON J.; LORDELLO, ANA LUISA L.; ANTAR, GUILHERME M.; AMARAL, MAIARA; SOARES, MARISI G.; TEMPONE, ANDRE G.; LAGO, JOAO HENRIQUE G.. Aporphine Alkaloids from Ocotea puberula with Anti-Trypanosoma Cruzi Potential - Activity of Dicentrine-beta-N-Oxide in the Plasma Membrane Electric Potentials. CHEMISTRY & BIODIVERSITY, MAR 2021. Web of Science Citations: 0. (18/07885-1, 18/10279-6)
LONDERO, VINICIUS S.; COSTA-SILVA, THAIS A.; TEMPONE, ANDRE G.; NAMIYAMA, GISLENE M.; THEVENARD, FERNANDA; ANTAR, GUILHERME M.; BAITELLO, JOAO B.; LAGO, JOAO HENRIQUE G.. Anti-Trypanosoma cruzi activity of costic acid isolated from Nectandra barbellata (Lauraceae) is associated with alterations in plasma membrane electric and mitochondrial membrane potentials. BIOORGANIC CHEMISTRY, v. 95, JAN 2020. Web of Science Citations: 0. (18/10279-6, 17/17044-1, 18/07885-1)
UMEHARA, ERIC; SILVA, THAIS A. COSTA; MENDES, VIVIANE M.; GUADAGNIN, RAFAEL C.; SARTORELLI, PATRICIA; TEMPONE, ANDRE G.; LAGO, JOAO HENRIQUE G.. Differential lethal action of C17:2 and C17:0 anacardic acid derivatives in Trypanosoma cruzi - A mechanistic study. BIOORGANIC CHEMISTRY, v. 102, SEP 2020. Web of Science Citations: 0. (18/10279-6, 18/07885-1)
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