João Henrique Ghilardi Lago
CV Lattes
GoogleMyCitations
ORCID
Ministério da Educação (Brasil). Universidade Federal do ABC (UFABC). Centro de Ciências Naturais e Humanas (CCNH) (Institutional affiliation for the last research proposal) Birthplace: Brazil
bachelor's at Bacharelado em Química from Instituto de Química - Universidade de São Paulo (1997), bachelor's at Licenciatura em Química from Faculdade de Educação - Universidade de São Paulo (1999) and doctorate at Química from Instituto de Química - Universidade de São Paulo (2002). Has experience in Chemistry, focusing on Chemistry of the Natural Products (Source: Lattes Curriculum)
| News published in Agência FAPESP Newsletter about the researcher |
| Biocompound from Atlantic Rainforest combats leishmaniasis and Chagas disease |
- Biomolecules from plant species of remnant areas of the Atlantic Forest and Cerrado to treat neglected tropical diseases - chemical and pharmacological aspects, AP.BTA.R
Abstract
In the present project will be selected plant species from Sao Paulo State biomes (Atlantic Forest and "Cerrado") aiming the structural characterization of natural products/semisynthetic derivatives with antiparasitic activity as well as evaluation of pre-clinical and toxicological potential, in continuation to the study begun in 2015 with FAPESP funding (project 2015/11936-2). Thus, di...
- Fapesp-DFG Joint Workshops 2017 Protease Research Biology: focus on neglected tropical diseases | Mainz - Alemanha, AO.R
- Use of chemodiversity of plant species in remaining areas of Atlantic Forest from São Paulo State in the selection of biologically active prototypes, AP.R
Abstract
In this project will be continued aiming the selection of plant species that occur in the remaining areas of the Atlantic Forest of São Paulo State, with the main purpose of conducting pharmacological studies, isolation and structural determination of active compounds, in addition to establishing relations structure/biologic activities obtained with compounds of vegetable matrices. This...
- EMBO Conference Series Chemical Biology 2014, AR.EXT
(Only some records are available in English at this moment)
- Biomolecules from Nectandra barbellata Coe-Teixeira (Lauraceae): use of a sustainable alternative method for extraction, molecular characterization and evaluation of antiparasitic potential, BP.DR
Abstract
Brazil has great biological diversity and can enjoy many species with unknown pharmacological properties. Phytochemical studies with different species of the genus Nectandra have shown great structural diversity of bioactive metabolites, however, there is no information in the literature related to the chemical composition and/or biological potential of the species Nectandra barbellata....
- Bioactive metabolites from Nectandra oppositifolia Ness. & Mart. (Lauraceae) - molecular characterization, in vitro and in vivo antiparasitic potential evaluation and determination of mechanism of action, BP.DR
Abstract
Plants are used for medicinal purposes since ancient times. Natural compounds extracted from plants have been highlighted as important sources of new therapeutic agents, used in the treatment of several ills, especially neglected diseases, such as leishmaniosis, Chagas disease among others. In this aspect, several studies are directed to evaluation of biological activities of natural co...
- Metabolic induction guided by genomic-mining strategies in Burkholderia thailandensis for the biosynthesis of antibiotic-like natural products, BP.PD
Abstract
Microorganisms participate in biological processes as long before man discover the possibilities for its systematic use. The production of compounds with pharmacological importance from these microscopic beings is well studied since the discovery of Penicillin. Currently, genomic analyzes have provided numerous new Natural Products from microorganisms. Therefore, this work aims to analy...
- Naturals and semisynthetics metabolites from twigs of Nectandra leucantha Ness & Mart. (Lauraceae): molecular characterization, potential evaluation and mechanism antitumoral against melanoma, BP.DD
Abstract
Malignant melanoma is a highly aggressive and lethal cancer resulted of mutations in the melanocytes, which in the later stages the current therapy is ineffective. Therefore, alternative therapies are required to induce the cytotoxic effects against tumor and at the same time do not damage the patient body. Plants produce and accumulate many compounds which have pharmacological effects,...
- Chemical identification and evaluation of antitumoral potential of metabolites of Guarea macrophylla ssp. tuberculata (Meliaceae), BP.MS
Abstract
Plants displayed a fundamental importance in the lives of all people. Natural products extracted from plants, have emerged as important sources of new therapeutic agents used in the treatment of several diseases, including cancer. Therefore, several studies were conducted to analysis of active principles of plants, with selective tumor cell activity, as well as investigating the mechani...
(Only some records are available in English at this moment)
- Dereplication profile of Nectandra oppositifolia Nees & Mart (Lauraceae) - identification and molecular caracterization of antiparasitic metabolites, BE.EP.DR
Abstract
Brazilian Atlantic forest is one of most important regions worldwide, considered as a biodiversity hotspot due to its high degree of biodiversity (plant, animals and microorganisms). Based in this aspect, the investigation of metabolites from different plants species from this biome could be a source of new prototypesto therapeutic treatment for several diseases, including neglected tro...
| 1 / 1 | Ongoing research grants |
| 7 / 5 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 9 / 4 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 20 / 13 | All research grants and scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 51 |
| Citations | 478 |
| Cit./Article | 9.4 |
| Data from Web of Science | |
DE ALMEIDA, BUANA C.; ARAUJO, BRUNO Q.; CARVALHO, ADONIAS A.; FREITAS, SAMYA DANIELLE L.; ALVES MACIEL, DAYANY DA S.; FERREIRA, ARI JOSE S.; TEMPONE, ANDRE G.; MARTINS, LIGIA F.; ALEXANDRE, TATIANA R.; CHAVES, MARIANA H.; et al. Antiprotozoal activity of extracts and isolated triterpenoids of `carnauba' (Copernicia prunifera) wax from Brazil. Pharmaceutical Biology, v. 54, n. 12, p. 3280-3284, DEC 2016. Web of Science Citations: 2.
GREECO, SIMONE DOS S.; FELIX, MARIA JULIA P.; LAGO, JOAO HENRIQUE G.; PINTO, ERIKA G.; TEMPONE, ANDRE G.; ROMOFF, PAULETE; FERREIRA, MARCELO JOSE P.; SARTORELLI, PATRICIA. Anti-trypanosomal Phenolic Derivatives from Baccharis uncinella. NATURAL PRODUCT COMMUNICATIONS, v. 9, n. 2, p. 171-173, FEB 2014. Web of Science Citations: 12.
GRECCO, SIMONE DOS S.; DORIGUETO, ANTONIO C.; LANDRE, IARA M.; SOARES, MARISI G.; MARTHO, KEVIN; LIMA, RICARDO; PASCON, RENATA C.; VALLIM, MARCELO A.; CAPELLO, TABATA M.; ROMOFF, PAULETE; et al. Structural Crystalline Characterization of Sakuranetin - An Antimicrobial Flavanone from Twigs of Baccharis retusa (Asteraceae). Molecules, v. 19, n. 6, p. 7528-7542, JUN 2014. Web of Science Citations: 4.
DA SILVA, ERICA BIOLCATI P.; SOARES, MARISI G.; MARIANE, BRUNA; VALLIM, MARCELO A.; PASCON, RENATA C.; SARTORELLI, PATRICIA; LAGO, JOAO HENRIQUE G.. The Seasonal Variation of the Chemical Composition of Essential Oils from Porcelia macrocarpa RE Fries (Annonaceae) and Their Antimicrobial Activity. Molecules, v. 18, n. 11, p. 13574-13587, NOV 2013. Web of Science Citations: 3.
BOU, DIEGO DINIS; LAGO, JOAO HENRIQUE G.; FIGUEIREDO, CARLOS R.; MATSUO, ALISSON L.; GUADAGNIN, RAFAEL C.; SOARES, MARISI G.; SARTORELLI, PATRICIA. Chemical Composition and Cytotoxicity Evaluation of Essential Oil from Leaves of Casearia Sylvestris, Its Main Compound alpha-Zingiberene and Derivatives. Molecules, v. 18, n. 8, p. 9477-9487, AUG 2013. Web of Science Citations: 31.
DAL PICOLO, CAMILLA R.; BEZERRA, MARIANA P.; GOMES, KAIO S.; PASSERO, LUIZ FELIPE D.; LAURENTI, MARCIA D.; MARTINS, EUDER GLENDES A.; SARTORELLI, PATRICIA; LAGO, JOAO HENRIQUE G.. Antileishmanial activity evaluation of adunchalcone, a new prenylated dihydrochalcone from Piper aduncum L.. Fitoterapia, v. 97, p. 28-33, SEP 2014. Web of Science Citations: 20.
LAGO, JOAO HENRIQUE G.; TOLEDO-ARRUDA, ALESSANDRA C.; MERNAK, MARCIA; BARROSA, KAIDU H.; MARTINS, MILTON A.; TIBERIO, IOLANDA F. L. C.; PRADO, CARLA M.. Structure-Activity Association of Flavonoids in Lung Diseases. Molecules, v. 19, n. 3, p. 3570-3595, MAR 2014. Web of Science Citations: 48.
MORAIS, THIAGO R.; DA COSTA-SILVA, THAIS A.; TEMPONE, ANDRE G.; BORBOREMA, SAMANTA ETEL T.; SCOTTI, MARCUS T.; DE SOUSA, RAQUEL MARIA F.; ARAUJO, ANA CAROLINA C.; DE OLIVEIRA, ALBERTO; DE MORAIS, SERGIO ANTONIO L.; SARTORELLI, PATRICIA; et al. Antiparasitic Activity of Natural and Semi-Synthetic Tirucallane Triterpenoids from Schinus terebinthifolius (Anacardiaceae): Structure/Activity Relationships. Molecules, v. 19, n. 5, p. 5761-5776, MAY 2014. Web of Science Citations: 8.
GRECCO, SIMONE DOS S.; REIMAO, JULIANA Q.; TEMPONE, ANDRE G.; SARTORELLI, PATRICIA; CUNHA, RODRIGO L. O. R.; ROMOFF, PAULETE; FERREIRA, MARCELO J. P.; FAVERO, ORIANA A.; LAGO, JOAO HENRIQUE G.. In vitro antileishmanial and antitrypanosomal activities of flavanones from Baccharis retusa DC. (Asteraceae). Experimental Parasitology, v. 130, n. 2, p. 141-145, FEB 2012. Web of Science Citations: 53.
JESUS, JESSICA A.; FRAGOSO, THAIS N.; YAMAMOTO, EDUARDO S.; LAURENTI, MARCIA D.; SILVA, MARCELO S.; FERREIRA, AUREA F.; LAGO, JOAO HENRIQUE G.; GOMES, GABRIELA S.; PASSERO, LUIZ FELIPE D.. Therapeutic effect of ursolic acid in experimental visceral leishmaniasis. INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE, v. 7, n. 1, p. 1-11, APR 2017. Web of Science Citations: 15.
VARELA, MARINA T.; DIAS, ROBERTO Z.; MARTINS, LIGIA F.; FERREIRA, DAIANE D.; TEMPONE, ANDRE G.; UENO, ANDERSON K.; LAGO, JOAO HENRIQUE G.; FERNANDES, JOAO PAULO S.. Gibbilimbol analogues as antiparasitic agents-Synthesis and biological activity against Trypanosoma cruzi and Leishmania (L.) infantum. Bioorganic & Medicinal Chemistry Letters, v. 26, n. 4, p. 1180-1183, FEB 15 2016. Web of Science Citations: 9.
BUANA C. DE ALMEIDA; BRUNO Q. ARAÚJO; ELCIO D. S. BARROS; SÂMYA D. L. FREITAS; DAYANY S. A. MACIEL; ARI J. S. FERREIRA; RAFAEL C. GUADAGNIN; GERARDO M. VIEIRA JÚNIOR; JOÃO H. G. LAGO; MARIANA H. CHAVES. Dammarane Triterpenoids from Carnauba, Copernicia prunifera (Miller) H. E. Moore (Arecaceae), Wax. Journal of the Brazilian Chemical Society, v. 28, n. 8, p. 1371-1376, Ago. 2017.
GAMES, ELLEN; GUERREIRO, MARINA; SANTANA, FERNANDA R.; PINHEIRO, NATHALIA M.; DE OLIVEIRA, EMERSON A.; LOPES, FERNANDA D. T. Q. S.; OLIVO, CLARICE R.; TIBERIO, IOLANDA F. L. C.; MARTINS, MILTON A.; LAGO, JOAO HENRIQUE G.; et al. Structurally Related Monoterpenes p-Cymene, Carvacrol and Thymol Isolated from Essential Oil from Leaves of Lippia sidoides Cham. (Verbenaceae) Protect Mice against Elastase-Induced Emphysema. Molecules, v. 21, n. 10, OCT 2016. Web of Science Citations: 9.
DIEGO D. BOU; AUGUSTO L. DOS SANTOS; CARLOS R. FIGUEIREDO; CAMYLA F. FARIAS; ALISSON L. MATSUO; RODRIGO O. S. KITAMURA; LEILA GIMENES; JOÃO H. G. LAGO; PATRICIA SARTORELLI. Dinor Casearin X, a New Cytotoxic Clerodane Diterpene from
SILVA, ROBSON E.; BALDIM, JOAO L.; CHAGAS-PAULA, DANIELA A.; SOARES, MARISI G.; LAGO, JOAO H. G.; GONCALVES, V, REGGIANI; NOVAES, ROMULO D.. Predictive metabolomic signatures of end-stage renal disease: A multivariate analysis of population-based data. Biochimie, v. 152, p. 14-30, SEP 2018. Web of Science Citations: 1.
GRECCO, SIMONE S.; COSTA-SILVA, THAIS A.; SOUSA, FERNANDA S.; CARGNELUTTI, STEFANO B.; UMEHARA, ERIC; MENDONCA, POLIANA S.; TEMPONE, ANDRE G.; LAGO, JOAO HENRIQUE G.. Neolignans isolated from twigs of Nectandra leucantha Ness & Mart (Lauraceae) displayed in vitro antileishmanial activity. Journal of Venomous Animals and Toxins including Tropical Diseases, v. 24, SEP 27 2018. Web of Science Citations: 0.
SANTOS, BEATRIZ MENDES; BEZERRA-SOUZA, ADRIANA; ARAGAKI, SONIA; RODRIGUES, ELIANA; UMEHARA, ERIC; GHILARDI LAGO, JOAO HENRIQUE; LAURENTI, MARCIA DALASTRA; RIBEIRO, SUSAN PEREIRA; DOMINGUES PASSERO, LUIZ FELIPE. Ethnopharmacology Study of Plants from Atlantic Forest with Leishmanicidal Activity. Evidence-based Complementary and Alternative Medicine, 2019. Web of Science Citations: 0.
ALVES CONSERVA, GEANNE A.; DA COSTA-SILVA, THAIS A.; AMARAL, MAIARA; ANTAR, GUILHERME M.; NEVES, BRUNO J.; ANDRADE, CAROLINA H.; TEMPONE, ANDRE G.; LAGO, JOAO HENRIQUE G.. Butenolides from Nectandra oppositifolia (Lauraceae) displayed anti-Trypanosoma cruzi activity via deregulation of mitochondria. Phytomedicine, v. 54, p. 302-307, FEB 15 2019. Web of Science Citations: 1.
BALDIM, JOAO LUIZ; DA SILVA, BRUNA LIDIANE; CHAGAS-PAULA, DANIELA APARECIDA; LAGO, JOAO HENRIQUE G.; SOARES, MARISI G.. A strategy for the identification of patterns in the biosynthesis of nonribosomal peptides by Betaproteobacteria species. SCIENTIFIC REPORTS, v. 7, SEP 4 2017. Web of Science Citations: 0.
DE SOUSA, FERNANDA S.; NUNES, EMILENE A.; GOMES, KAIO S.; CERCHIARO, GISELLE; LAGO, JOAO HENRIQUE G.. Genotoxic and cytotoxic effects of neolignans isolated from Nectandra leucantha (Lauraceae). TOXICOLOGY IN VITRO, v. 55, p. 116-123, MAR 2019. Web of Science Citations: 0.
BRITO, JULIANA R.; DA COSTA-SILVA, THAIS A.; TEMPONE, ANDRE G.; FERREIRA, EDGARD A.; LAGO, JOAO HENRIQUE G.. Dibenzylbutane neolignans from Saururus cernuus L. (Saururaceae) displayed anti-Trypanosoma cruzi activity via alterations in the mitochondrial membrane potential. Fitoterapia, v. 137, SEP 2019. Web of Science Citations: 0.
VARELA, MARINA T.; COSTA-SILVA, THAIS A.; LAGO, JOAO HENRIQUE G.; TEMPONE, ANDRE G.; FERNANDES, JOAO PAULO S.. Evaluation of the antitrypanosoma activity and SAR study of novel LINS03 derivatives. BIOORGANIC CHEMISTRY, v. 89, AUG 2019. Web of Science Citations: 0.
AMARAL, MAIARA; DE SOUSA, FERNANDA S.; SILVA, THAIS A. COSTA; JUNIOR, ANDRES JIMENEZ G.; TANIWAKI, NOEMI N.; JOHNS, DEID RE M.; LAGO, JOAO HENRIQUE G.; ANDERSON, EDWARD A.; TEMPONE, ANDRE G.. A semi-synthetic neolignan derivative from dihydrodieugenol B selectively affects the bioenergetic system of Leishmania infantum and inhibits cell division. SCIENTIFIC REPORTS, v. 9, APR 16 2019. Web of Science Citations: 2.
DA COSTA-SILVA, THAIS A.; ALVES CONSERVA, GEANNE A.; GALISTEO, JR., ANDRES J.; TEMPONE, ANDRE G.; LAGO, JOAO HENRIQUE G.. Antileishmanial activity and immunomodulatory effect of secosubamolide, a butanolide isolated from Nectandra oppositifolia (Lauraceae). Journal of Venomous Animals and Toxins including Tropical Diseases, v. 25, AUG 19 2019. Web of Science Citations: 0.
DE SOUSA, CAROLINA BRUNO; GANGADHAR, KATKAM N.; MORAIS, THIAGO R.; CONSERVA, GEANNE A. A.; VIZETTO-DUARTE, CATARINA; PEREIRA, HUGO; LAURENTI, MARCIA D.; CAMPINO, LENEA; LEVY, DEBORA; UEMI, MIRIAM; et al. Antileishmanial activity of meroditerpenoids from the macroalgae Cystoseira baccata. Experimental Parasitology, v. 174, p. 1-9, MAR 2017. Web of Science Citations: 12.
GRECCO, SIMONE S.; COSTA-SILVA, THAIS A.; JERZ, GEROLD; DE SOUSA, FERNANDA S.; LONDERO, VINICIUS S.; GALUPPO, MARIANA K.; LIMA, MARTA L.; NEVES, BRUNO J.; ANDRADE, CAROLINA H.; TEMPONE, ANDRE G.; et al. Neolignans from leaves of Nectandra leucantha (Lauraceae) display in vitro antitrypanosomal activity via plasma membrane and mitochondrial damages. Chemico-Biological Interactions, v. 277, p. 55-61, NOV 1 2017. Web of Science Citations: 7.
FERREIRA, DAIANE D.; SOUSA, FERNANDA S.; COSTA-SILVA, THAIS A.; REIMAO, JULIANA Q.; TORRECILHAS, ANA C.; JOHNS, DEIDRE M.; SEAR, CLAIRE E.; HONORIO, KATHIA M.; LAGO, JOAO HENRIQUE G.; ANDERSON, EDWARD A.; et al. Dehydrodieugenol B derivatives as antiparasitic agents: Synthesis and biological activity against Trypanosoma cruzi. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v. 176, p. 162-174, AUG 15 2019. Web of Science Citations: 1.
BRITO, JULIANA R.; PASSERO, LUIZ FELIPE D.; BEZERRA-SOUZA, ADRIANA; LAURENTI, MARCIA D.; ROMOFF, PAULETE; BARBOSA, HENRIQUE; FERREIRA, EDGARD A.; LAGO, JOAO HENRIQUE G.. Antileishmanial activity and ultrastructural changes of related tetrahydrofuran dineolignans isolated from Saururus cernuus L. (Saururaceae). Journal of Pharmacy and Pharmacology, v. 71, n. 12, p. 1871-1878, DEC 2019. Web of Science Citations: 0.
MACIEL, DAYANY DA SILVA A.; FREITAS, VIVIANE P.; ALVES CONSERVA, GEANNE A.; ALEXANDRE, TATIANA R.; PURISCO, SONIA U.; TEMPONE, ANDRE G.; MELHEM, MARCIA SOUZA C.; KATO, MASSUO J.; GUIMARAES, ELSIE F.; LAGO, JOAO HENRIQUE G.. Bioactivity-guided isolation of laevicarpin, an antitrypanosomal and anticryptococcal lactam from Piper laevicarpu (Piperaceae). Fitoterapia, v. 111, p. 24-28, JUN 2016. Web of Science Citations: 7.
VARELA, MARINA T.; LIMA, MARTA L.; GALUPPO, MARIANA K.; TEMPONE, ANDRE G.; DE OLIVEIRA, ALBERTO; LAGO, JOAO HENRIQUE G.; FERNANDES, JOAO PAULO S.. New alkenyl derivative from Piper malacophyllum and analogues: Antiparasitic activity against Trypanosoma cruzi and Leishmania infantum. CHEMICAL BIOLOGY & DRUG DESIGN, v. 90, n. 5, p. 1007-1011, NOV 2017. Web of Science Citations: 8.
DE ALMEIDA, BUANA C.; ARAUJO, BRUNO Q.; CARVALHO, ADONIAS A.; FREITAS, SAMYA DANIELLE L.; ALVES MACIEL, DAYANY DA S.; FERREIRA, ARI JOSE S.; TEMPONE, ANDRE G.; MARTINS, LIGIA F.; ALEXANDRE, TATIANA R.; CHAVES, MARIANA H.; et al. Antiprotozoal activity of extracts and isolated triterpenoids of `carnauba' (Copernicia prunifera) wax from Brazil. Pharmaceutical Biology, v. 54, n. 12, p. 3280-3284, DEC 2016. Web of Science Citations: 2.
GREECO, SIMONE DOS S.; FELIX, MARIA JULIA P.; LAGO, JOAO HENRIQUE G.; PINTO, ERIKA G.; TEMPONE, ANDRE G.; ROMOFF, PAULETE; FERREIRA, MARCELO JOSE P.; SARTORELLI, PATRICIA. Anti-trypanosomal Phenolic Derivatives from Baccharis uncinella. NATURAL PRODUCT COMMUNICATIONS, v. 9, n. 2, p. 171-173, FEB 2014. Web of Science Citations: 12.
GRECCO, SIMONE DOS S.; DORIGUETO, ANTONIO C.; LANDRE, IARA M.; SOARES, MARISI G.; MARTHO, KEVIN; LIMA, RICARDO; PASCON, RENATA C.; VALLIM, MARCELO A.; CAPELLO, TABATA M.; ROMOFF, PAULETE; et al. Structural Crystalline Characterization of Sakuranetin - An Antimicrobial Flavanone from Twigs of Baccharis retusa (Asteraceae). Molecules, v. 19, n. 6, p. 7528-7542, JUN 2014. Web of Science Citations: 4.
DA SILVA, ERICA BIOLCATI P.; SOARES, MARISI G.; MARIANE, BRUNA; VALLIM, MARCELO A.; PASCON, RENATA C.; SARTORELLI, PATRICIA; LAGO, JOAO HENRIQUE G.. The Seasonal Variation of the Chemical Composition of Essential Oils from Porcelia macrocarpa RE Fries (Annonaceae) and Their Antimicrobial Activity. Molecules, v. 18, n. 11, p. 13574-13587, NOV 2013. Web of Science Citations: 3.
BOU, DIEGO DINIS; LAGO, JOAO HENRIQUE G.; FIGUEIREDO, CARLOS R.; MATSUO, ALISSON L.; GUADAGNIN, RAFAEL C.; SOARES, MARISI G.; SARTORELLI, PATRICIA. Chemical Composition and Cytotoxicity Evaluation of Essential Oil from Leaves of Casearia Sylvestris, Its Main Compound alpha-Zingiberene and Derivatives. Molecules, v. 18, n. 8, p. 9477-9487, AUG 2013. Web of Science Citations: 31.
DAL PICOLO, CAMILLA R.; BEZERRA, MARIANA P.; GOMES, KAIO S.; PASSERO, LUIZ FELIPE D.; LAURENTI, MARCIA D.; MARTINS, EUDER GLENDES A.; SARTORELLI, PATRICIA; LAGO, JOAO HENRIQUE G.. Antileishmanial activity evaluation of adunchalcone, a new prenylated dihydrochalcone from Piper aduncum L.. Fitoterapia, v. 97, p. 28-33, SEP 2014. Web of Science Citations: 20.
LAGO, JOAO HENRIQUE G.; TOLEDO-ARRUDA, ALESSANDRA C.; MERNAK, MARCIA; BARROSA, KAIDU H.; MARTINS, MILTON A.; TIBERIO, IOLANDA F. L. C.; PRADO, CARLA M.. Structure-Activity Association of Flavonoids in Lung Diseases. Molecules, v. 19, n. 3, p. 3570-3595, MAR 2014. Web of Science Citations: 48.
MORAIS, THIAGO R.; DA COSTA-SILVA, THAIS A.; TEMPONE, ANDRE G.; BORBOREMA, SAMANTA ETEL T.; SCOTTI, MARCUS T.; DE SOUSA, RAQUEL MARIA F.; ARAUJO, ANA CAROLINA C.; DE OLIVEIRA, ALBERTO; DE MORAIS, SERGIO ANTONIO L.; SARTORELLI, PATRICIA; et al. Antiparasitic Activity of Natural and Semi-Synthetic Tirucallane Triterpenoids from Schinus terebinthifolius (Anacardiaceae): Structure/Activity Relationships. Molecules, v. 19, n. 5, p. 5761-5776, MAY 2014. Web of Science Citations: 8.
GRECCO, SIMONE DOS S.; REIMAO, JULIANA Q.; TEMPONE, ANDRE G.; SARTORELLI, PATRICIA; CUNHA, RODRIGO L. O. R.; ROMOFF, PAULETE; FERREIRA, MARCELO J. P.; FAVERO, ORIANA A.; LAGO, JOAO HENRIQUE G.. In vitro antileishmanial and antitrypanosomal activities of flavanones from Baccharis retusa DC. (Asteraceae). Experimental Parasitology, v. 130, n. 2, p. 141-145, FEB 2012. Web of Science Citations: 53.
JESUS, JESSICA A.; FRAGOSO, THAIS N.; YAMAMOTO, EDUARDO S.; LAURENTI, MARCIA D.; SILVA, MARCELO S.; FERREIRA, AUREA F.; LAGO, JOAO HENRIQUE G.; GOMES, GABRIELA S.; PASSERO, LUIZ FELIPE D.. Therapeutic effect of ursolic acid in experimental visceral leishmaniasis. INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE, v. 7, n. 1, p. 1-11, APR 2017. Web of Science Citations: 15.
ALVES CONSERVA, GEANNE A.; DA COSTA-SILVA, THAIS A.; AMARAL, MAIARA; ANTAR, GUILHERME M.; NEVES, BRUNO J.; ANDRADE, CAROLINA H.; TEMPONE, ANDRE G.; LAGO, JOAO HENRIQUE G.. Butenolides from Nectandra oppositifolia (Lauraceae) displayed anti-Trypanosoma cruzi activity via deregulation of mitochondria. Phytomedicine, v. 54, p. 302-307, FEB 15 2019. Web of Science Citations: 1.
BALDIM, JOAO LUIZ; DA SILVA, BRUNA LIDIANE; CHAGAS-PAULA, DANIELA APARECIDA; LAGO, JOAO HENRIQUE G.; SOARES, MARISI G.. A strategy for the identification of patterns in the biosynthesis of nonribosomal peptides by Betaproteobacteria species. SCIENTIFIC REPORTS, v. 7, SEP 4 2017. Web of Science Citations: 0.
DE SOUSA, FERNANDA S.; NUNES, EMILENE A.; GOMES, KAIO S.; CERCHIARO, GISELLE; LAGO, JOAO HENRIQUE G.. Genotoxic and cytotoxic effects of neolignans isolated from Nectandra leucantha (Lauraceae). TOXICOLOGY IN VITRO, v. 55, p. 116-123, MAR 2019. Web of Science Citations: 0.
BRITO, JULIANA R.; DA COSTA-SILVA, THAIS A.; TEMPONE, ANDRE G.; FERREIRA, EDGARD A.; LAGO, JOAO HENRIQUE G.. Dibenzylbutane neolignans from Saururus cernuus L. (Saururaceae) displayed anti-Trypanosoma cruzi activity via alterations in the mitochondrial membrane potential. Fitoterapia, v. 137, SEP 2019. Web of Science Citations: 0.
VARELA, MARINA T.; COSTA-SILVA, THAIS A.; LAGO, JOAO HENRIQUE G.; TEMPONE, ANDRE G.; FERNANDES, JOAO PAULO S.. Evaluation of the antitrypanosoma activity and SAR study of novel LINS03 derivatives. BIOORGANIC CHEMISTRY, v. 89, AUG 2019. Web of Science Citations: 0.
AMARAL, MAIARA; DE SOUSA, FERNANDA S.; SILVA, THAIS A. COSTA; JUNIOR, ANDRES JIMENEZ G.; TANIWAKI, NOEMI N.; JOHNS, DEID RE M.; LAGO, JOAO HENRIQUE G.; ANDERSON, EDWARD A.; TEMPONE, ANDRE G.. A semi-synthetic neolignan derivative from dihydrodieugenol B selectively affects the bioenergetic system of Leishmania infantum and inhibits cell division. SCIENTIFIC REPORTS, v. 9, APR 16 2019. Web of Science Citations: 2.
DA COSTA-SILVA, THAIS A.; ALVES CONSERVA, GEANNE A.; GALISTEO, JR., ANDRES J.; TEMPONE, ANDRE G.; LAGO, JOAO HENRIQUE G.. Antileishmanial activity and immunomodulatory effect of secosubamolide, a butanolide isolated from Nectandra oppositifolia (Lauraceae). Journal of Venomous Animals and Toxins including Tropical Diseases, v. 25, AUG 19 2019. Web of Science Citations: 0.
DE SOUSA, CAROLINA BRUNO; GANGADHAR, KATKAM N.; MORAIS, THIAGO R.; CONSERVA, GEANNE A. A.; VIZETTO-DUARTE, CATARINA; PEREIRA, HUGO; LAURENTI, MARCIA D.; CAMPINO, LENEA; LEVY, DEBORA; UEMI, MIRIAM; et al. Antileishmanial activity of meroditerpenoids from the macroalgae Cystoseira baccata. Experimental Parasitology, v. 174, p. 1-9, MAR 2017. Web of Science Citations: 12.
GRECCO, SIMONE S.; COSTA-SILVA, THAIS A.; JERZ, GEROLD; DE SOUSA, FERNANDA S.; LONDERO, VINICIUS S.; GALUPPO, MARIANA K.; LIMA, MARTA L.; NEVES, BRUNO J.; ANDRADE, CAROLINA H.; TEMPONE, ANDRE G.; et al. Neolignans from leaves of Nectandra leucantha (Lauraceae) display in vitro antitrypanosomal activity via plasma membrane and mitochondrial damages. Chemico-Biological Interactions, v. 277, p. 55-61, NOV 1 2017. Web of Science Citations: 7.
FERREIRA, DAIANE D.; SOUSA, FERNANDA S.; COSTA-SILVA, THAIS A.; REIMAO, JULIANA Q.; TORRECILHAS, ANA C.; JOHNS, DEIDRE M.; SEAR, CLAIRE E.; HONORIO, KATHIA M.; LAGO, JOAO HENRIQUE G.; ANDERSON, EDWARD A.; et al. Dehydrodieugenol B derivatives as antiparasitic agents: Synthesis and biological activity against Trypanosoma cruzi. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v. 176, p. 162-174, AUG 15 2019. Web of Science Citations: 1.
GOMES, KAIO S.; DA COSTA-SILVA, THAIS A.; OLIVEIRA, IGOR H.; AGUILAR, ANDREA M.; OLIVEIRA-SILVA, DIOGO; UEMI, MIRIAM; SILVA, WENDER A.; MELO, LENNINE R.; ANDRADE, CARLOS KLEBER Z.; TEMPONE, ANDRE G.; et al. Structure-activity relationship study of antitrypanosomal chalcone derivatives using multivariate analysis. Bioorganic & Medicinal Chemistry Letters, v. 29, n. 12, p. 1459-1462, JUN 15 2019. Web of Science Citations: 0.
GRECCO, SIMONE S.; COSTA-SILVA, THAIS A.; JERZ, GEROLD; DE SOUSA, FERNANDA S.; ALVES CONSERVA, GEANNE A.; MESQUITA, JULIANA T.; GALUPPO, MARIANA K.; TEMPONE, ANDRE G.; NEVES, BRUNO J.; ANDRADE, CAROLINA H.; et al. Antitrypanosomal activity and evaluation of the mechanism of action of dehydrodieugenol isolated from Nectandra leucantha (Lauraceae) and its methylated derivative against Trypanosoma cruzi. Phytomedicine, v. 24, p. 62-67, JAN 15 2017. Web of Science Citations: 7.
UENO, ANDERSON K.; BARCELLOS, ALINE F.; COSTA-SILVA, THAIS A.; MESQUITA, JULIANA T.; FERREIRA, DAIANE D.; TEMPONE, ANDRE G.; ROMOFF, PAULETE; ANTAR, GUILHERME M.; LAGO, JOAO HENRIQUE G.. Antitrypanosomal activity and evaluation of the mechanism of action of diterpenes from aerial parts of Baccharis retusa (Asteraceae). Fitoterapia, v. 125, p. 55-58, MAR 2018. Web of Science Citations: 7.