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Adriana Castello Costa Girardi

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Secretaria da Saúde (São Paulo - Estado). Hospital das Clínicas da Faculdade de Medicina da USP (HCFMUSP). Instituto do Coração Professor Euryclides de Jesus Zerbini (INCOR)  (Institutional affiliation for the last research proposal)
Birthplace: Brazil

Adriana C. Girardi received a B.A. in Pharmacology and Biochemistry (1996) and a Ph.D. (2002) in Physiology at University of São Paulo. From 2002 to 2005, she was a postdoctoral fellow in the Aronson lab (Department of Internal Medicine, Section of Nephrology, Yale University). Currently, she is a principal investigator in the Laboratory of Genetics and Molecular Cardiology, Incor, HC-USP and Professor at FMUSP. She has experience in Renal Physiology, Cardiorenal Pharmacology and Biochemistry. Her major scientific interest is understanding blood pressure regulation and cardiovascular disease. Recently, her research group has investigated how therapies for diabetes affect cardiovascular disease progression and hypertension. javascript:void(0) (Source: Lattes Curriculum)

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FAPESP support in numbers * Updated January 25, 2020
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Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (26)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Publications25
Citations610
Cit./Article24.4
Data from Web of Science

CRAJOINAS, RENATO O.; POLIDORO, JULIANO Z.; CARNEIRO DE MORAIS, CARLA P. A.; CASTELO-BRANCO, REGIANE C.; GIRARDI, ADRIANA C. C.. Angiotensin II counteracts the effects of cAMP/PKA on NHE3 activity and phosphorylation in proximal tubule cells. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, v. 311, n. 5, p. C768-C776, . Web of Science Citations: 7. (13/10619-8, 12/10146-0)

ARRUDA-JUNIOR, DANIEL F.; MARTINS, FLAVIA L.; DARIOLLI, RAFAEL; JENSEN, LEONARDO; ANTONIO, EDNEI L.; DOS SANTOS, LEONARDO; TUCCI, PAULO J. F.; GIRARDI, ADRIANA C. C.. Dipeptidyl Peptidase IV Inhibition Exerts Renoprotective Effects in Rats with Established Heart Failure. FRONTIERS IN PHYSIOLOGY, v. 7, . Web of Science Citations: 8. (13/10619-8)

CARNEIRO DE MORAIS, CARLA P.; POLIDORO, JULIANO Z.; RALPH, DONNA L.; PESSOA, THAISSA D.; OLIVEIRA-SOUZA, MARIA; BARAUNA, VALERIO G.; REBOUCAS, NANCY A.; MALNIC, GERHARD; MCDONOUGH, ALICIA A.; GIRARDI, ADRIANA C. C.. Proximal tubule NHE3 activity is inhibited by beta-arrestin-biased angiotensin II type 1 receptor signaling. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, v. 309, n. 8, p. C541-C550, . Web of Science Citations: 5. (13/10619-8, 13/50384-0, 12/10146-0)

CRAJOINAS, R. O.; PESSOA, T. D.; RODRIGUES, M. V.; MALNIC, G.; GIRARDI, A. C. C.. Changes in the activity and expression of protein phosphatase-1 accompany the differential regulation of NHE3 before and after the onset of hypertension in spontaneously hypertensive rats. ACTA PHYSIOLOGICA, v. 211, n. 2, p. 395-408, . Web of Science Citations: 6. (12/10146-0)

INOUE, BRUNA H.; ARRUDA-JUNIOR, DANIEL F.; CAMPOS, LUCIENE C. G.; BARRETO, ANA LUIZA T.; RODRIGUES, MARILIZA V.; KRIEGER, JOSE EDUARDO; GIRARDI, ADRIANA C. C.. Progression of microalbuminuria in SHR is associated with lower expression of critical components of the apical endocytic machinery in the renal proximal tubule. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, v. 305, n. 2, p. F216-F226, . Web of Science Citations: 7. (12/10146-0)

PONTES, ROBERTO B.; CRAJOINAS, RENATO O.; NISHI, ERIKA E.; OLIVEIRA-SALES, ELIZABETH B.; GIRARDI, ADRIANA C.; CAMPOS, RUY R.; BERGAMASCHI, CASSIA T.. Renal nerve stimulation leads to the activation of the Na+/H+ exchanger isoform 3 via angiotensin II type I receptor. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, v. 308, n. 8, p. F848-F856, . Web of Science Citations: 21. (13/22522-9, 12/10146-0)

QUEIROZ-LEITE, GABRIELLA D.; CRAJOINAS, RENATO O.; NERI, ELIDA A.; BEZERRA, CAMILA N. A.; GIRARDI, ADRIANA C. C.; REBOUCAS, NANCY AMARAL; MALNIC, GERHARD. Fructose Acutely Stimulates NHE3 Activity in Kidney Proximal Tubule. Kidney & Blood Pressure Research, v. 36, n. 1, p. 320-334, . Web of Science Citations: 18. (08/58287-5)

CRAJOINAS, RENATO O.; ORICCHIO, FELIPE T.; PESSOA, THAISSA D.; PACHECO, BRUNA P. M.; LESSA, LUCILIA M. A.; MALNIC, GERHARD; GIRARDI, ADRIANA C. C.. Mechanisms mediating the diuretic and natriuretic actions of the incretin hormone glucagon-like peptide-1. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, v. 301, n. 2, p. F355-F363, . Web of Science Citations: 117.

CARRARO-LACROIX, LUCIENE R.; LESSA, LUCILIA M. A.; BEZERRA, CAMILA N. A.; PESSOA, THAISSA D.; SOUZA-MENEZES, JACKSON; MORALES, MARCELO M.; GIRARDI, ADRIANA C. C.; MALNIC, GERHARD. Role of CFTR and ClC-5 in Modulating Vacuolar H+-ATPase Activity in Kidney Proximal Tubule. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, v. 26, n. 4-5, p. 563-576, . Web of Science Citations: 16. (04/01683-5)

GIRARDI, ADRIANA C. C.; DI SOLE, FRANCESCA. Deciphering the mechanisms of the Na+/H+ exchanger-3 regulation in organ dysfunction. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, v. 302, n. 11, p. C1569-C1587, . Web of Science Citations: 45.

GIRARDI, ADRIANA CASTELLO COSTA; FUKUDA, LÍVIA EMY; ROSSONI, LUCIANA VENTURINI; MALNIC, GERHARD; REBOUÇAS, NANCY AMARAL. Dipeptidyl peptidase IV inhibition downregulates Na+-H+ exchanger NHE3 in rat renal proximal tubule. American Journal of Physiology : Renal Physiology, v. 294, n. 2, p. F414-F422, . (04/01683-5)

BERALDO, JULIANA ISA; BENETTI, ACARIS; BORGES-JUNIOR, FLAVIO ARAUJO; ARRUDA-JUNIOR, DANIEL F.; MARTINS, FLAVIA LETICIA; JENSEN, LEONARDO; DARIOLLI, RAFAEL; SHIMIZU, MARIA HELOISA; SEGURO, ANTONIO C.; LUCHI, WEVERTON M.; et al. Cardioprotection Conferred by Sitagliptin Is Associated with Reduced Cardiac Angiotensin II/Angiotensin-(1-7) Balance in Experimental Chronic Kidney Disease. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 20, n. 8, . Web of Science Citations: 1. (13/10619-8, 16/22140-7)

VEIRAS, LUCIANA C.; GIRARDI, ADRIANA C. C.; CURRY, JOSHUA; PEI, LEI; RALPH, DONNA L.; TRAN, AN; CASTELO-BRANCO, REGIANE C.; PASTOR-SOLER, NURIA; ARRANZ, CRISTINA T.; YU, ALAN S. L.; et al. Sexual Dimorphic Pattern of Renal Transporters and Electrolyte Homeostasis. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, v. 28, n. 12, p. 3504-3517, . Web of Science Citations: 39. (12/10146-0)

GIANNOCCO, GISELE; OLIVEIRA, KELEN C.; CRAJOINAS, RENATO O.; VENTURINI, GABRIELA; SALLES, THIAGO A.; FONSECA-ALANIZ, MIRIAM H.; MACIEL, RUI M. B.; GIRARDI, ADRIANA C. C.. Dipeptidyl peptidase IV inhibition upregulates GLUT4 translocation and expression in heart and skeletal muscle of spontaneously hypertensive rats. European Journal of Pharmacology, v. 698, n. 1-3, p. 74-86, . Web of Science Citations: 34.

CARRARO-LACROIX, LUCIENE R.; MALNIC, GERHARD; GIRARDI, ADRIANA C. C.. Regulation of Na+/H+ exchanger NHE3 by glucagon-like peptide 1 receptor agonist exendin-4 in renal proximal tubule cells. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, v. 297, n. 6, p. F1647-F1655, . Web of Science Citations: 77. (04/01683-5)

YOSHIZAKI, AMANDA; ANTONIO, EDNEI LUIZ; SILVA JUNIOR, JOSE ANTONIO; CRAJOINAS, RENATO OLIVEIRA; SILVA, FLAVIO ANDRE; COSTA GIRARDI, ADRIANA CASTELLO; BOCALINI, DANILO SALES; PORTES, LESLIE ANDREWS; NEVES DOS SANTOS, LUIS FELIPE; CARLOS, FERNANDO PEREIRA; et al. Swimming Training Improves Myocardial Mechanics, Prevents Fibrosis, and Alters Expression of Ca2+ Handling Proteins in Older Rats. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, v. 73, n. 4, p. 468-474, . Web of Science Citations: 0. (13/10619-8, 15/11028-9)

VIEIRA, STELLA DE SOUZA; ANTONIO, EDNEI LUIZ; DE MELO, BRUNNO LEMES; PORTES, LESLIE ANDREWS; MONTEMOR, JAIRO; OLIVEIRA, HELENITA ANTONIA; MARTINS, FLAVIA LETICIA; ZOGBI, CAMILA; GIRARDI, ADRIANA COSTA; SILVA, JR., JOSE ANTONIO; et al. Exercise Training Potentiates The Cardioprotective Effects of Stem Cells Post-infarction. HEART LUNG AND CIRCULATION, v. 28, n. 2, p. 263-271, . Web of Science Citations: 2. (13/10619-8, 15/11028-9)

CRAJOINAS, RENATO O.; POLIDORO, JULIANO Z.; GIRARDI, ADRIANA C. C.. The potential role of myosin motor proteins in mediating the subcellular distribution of NHE3 in the renal proximal tubule. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, v. 316, n. 5, p. F986-F992, . Web of Science Citations: 0. (16/22140-7)

SALLES, THIAGO DE ALMEIDA; ZOGBI, CAMILA; DE LIMA, THAIS MARTINS; CARNEIRO, CAMILA DE GODOI; GARCEZ, ALEXANDRE TELES; BARBEIRO, HERMES VIEIRA; ANTONIO, EDNEI LUIZ; DOS SANTOS, LEONARDO; PEREIRA, ALEXANDRE DA COSTA; FERREIRA TUCCI, PAULO JOSE; et al. The contributions of dipeptidyl peptidase IV to inflammation in heart failure. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, v. 310, n. 11, p. H1760-H1772, . Web of Science Citations: 11. (11/07402-1, 13/10619-8, 09/54225-8)

LUCHI, WEVERTON M.; SHIMIZU, MARIA HELOISA M.; CANALE, DANIELE; GOIS, PEDRO HENRIQUE F.; DE BRAGANCA, ANA CAROLINA; VOLPINI, RILDO A.; GIRARDI, ADRIANA C. C.; SEGURO, ANTONIO C.. Vitamin D deficiency is a potential risk factor for contrast-induced nephropathy. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, v. 309, n. 3, p. R215-R222, . Web of Science Citations: 10. (12/10146-0)

DOS SANTOS, LEONARDO; SALLES, THIAGO A.; ARRUDA-JUNIOR, DANIEL F.; CAMPOS, LUCIENE C. G.; PEREIRA, ALEXANDRE C.; BARRETO, ANA LUIZA T.; ANTONIO, EDNEI L.; MANSUR, ALFREDO J.; TUCCI, PAULO J. F.; KRIEGER, JOSE E.; et al. Circulating Dipeptidyl Peptidase IV Activity Correlates With Cardiac Dysfunction in Human and Experimental Heart Failure. Circulation-Heart Failure, v. 6, n. 5, p. 1029-1038, . Web of Science Citations: 76. (09/54225-8, 12/10146-0)

SAVIGNANO, FERNANDA A.; CRAJOINAS, RENATO O.; PACHECO, BRUNA P. M.; CAMPOS, LUCIENE C. G.; SHIMIZU, MARIA HELOISA M.; SEGURO, ANTONIO CARLOS; GIRARDI, ADRIANA C. C.. Attenuated diuresis and natriuresis in response to glucagon-like peptide-1 in hypertensive rats are associated with lower expression of the glucagon-like peptide-1 receptor in the renal vasculature. European Journal of Pharmacology, v. 811, p. 38-47, . Web of Science Citations: 4. (13/10619-8, 12/10146-0)

PESSOA, THAISSA DANTAS; GASTALHO CAMPOS, LUCIENE CRISTINA; CARRARO-LACROIX, LUCIENE; GIRARDI, ADRIANA C. C.; MALNIC, GERHARD. Functional Role of Glucose Metabolism, Osmotic Stress, and Sodium-Glucose Cotransporter Isoform-Mediated Transport on Na+/H+ Exchanger Isoform 3 Activity in the Renal Proximal Tubule. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, v. 25, n. 9, p. 2028-2039, . Web of Science Citations: 54. (08/58287-5, 12/10146-0)

CARRARO-LACROIX, LUCIENE R.; MALNIC, GERHARD; GIRARDI, ADRIANA C. C.. Regulation of Na+/H+ exchanger NHE3 by glucagon-like peptide 1 receptor agonist exendin-4 in renal proximal tubule cells. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, v. 297, n. 6, p. F1647-F1655, . Web of Science Citations: 77. (04/01683-5)

CRAJOINAS, RENATO O.; POLIDORO, JULIANO Z.; GIRARDI, ADRIANA C. C.. The potential role of myosin motor proteins in mediating the subcellular distribution of NHE3 in the renal proximal tubule. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, v. 316, n. 5, p. F986-F992, . Web of Science Citations: 0. (16/22140-7)

VIEIRA, STELLA DE SOUZA; ANTONIO, EDNEI LUIZ; DE MELO, BRUNNO LEMES; PORTES, LESLIE ANDREWS; MONTEMOR, JAIRO; OLIVEIRA, HELENITA ANTONIA; MARTINS, FLAVIA LETICIA; ZOGBI, CAMILA; GIRARDI, ADRIANA COSTA; SILVA, JR., JOSE ANTONIO; et al. Exercise Training Potentiates The Cardioprotective Effects of Stem Cells Post-infarction. HEART LUNG AND CIRCULATION, v. 28, n. 2, p. 263-271, . Web of Science Citations: 2. (13/10619-8, 15/11028-9)

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