- Research Grants
Francesco Brugnera Teixeira in research grants and scholarships supported by FAPESP.
Cell invasion by the different infective forms of Trypanosoma cruzi, the causative parasite of Chagas disease, involves several mechanisms which culminate in entry of T. cruzi into host cells. Numerous studies have been conducted in order to identify surface proteins related to cell invasion, but mostly from metacyclic and tissue culture trypomastigotes forms. However, little attention...
This project aims to solve the tridimensional structure of the P21 protein of T. cruzi using multidimensional, high-resolution NMR spectroscopy, and to investigate its interaction with the CXCR4 chemokine receptor. To achieve this goal, the NMR spectra necessary to finalize the complete assignments, and the required NOESY-type spectra for structure calculation we will acquired in an 800...
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
(References retrieved automatically from State of São Paulo Research Institutions)
TEIXEIRA, Francesco Brugnera. Estudos biofísicos da proteína P21 de Trypanosoma cruzi. Tese (Doutorado) - Instituto de Física de São Carlos. Universidade de São Paulo (USP). São Carlos. (12/21153-7)