CV Lattes
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Universidade de São Paulo (USP). Faculdade de Medicina de Ribeirão Preto (FMRP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Dr. Edwin Tamashiro obtained his MD and PhD degree from the Ribeirão Preto Medical School and completed his training in Otorhinolaryngology at the Clinics Hospital of the Ribeirão Preto Medical School. He completed his research fellowship at the Division of Rhinology of the University of Pennsylvania (2007-2008, under the supervision of Dr. James Palmer and Dr. Noam Cohen) followed by a post-doctoral fellowship at the Department of Microbiology in 2014 (Dr. Jeffrey Weiser). Currently is appointed as an Associate Professor at the Department of Ophthalmology, Otorhinolaryngology and Head and Neck Surgery at the Ribeirão Preto Medical School, University of Sao Paulo. (Source: Lattes Curriculum)
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The study of the resident microbiota by molecular techniques has revolutionized the understanding of the sinonasal flora in patients with chronic rhinosinusitis (CRS), allowing the quantification and identification of various non-culturable germs. Most of these studies have carried out cross-sectional with a single evaluation, in an attempt to justify possible relations with the pathogene…
The altered expression of microRNAs (miRNAs) has been recently described in patients with Chronic Rhinosinusitis and other inflammatory diseases in airways, such as asthma. However, the correct relationship between distorted miRNA expression and altered production of proteins (anti-inflammatory either pro-inflammatory) in Chronic Rhinosinusitis is poorly understood. This study aims to eva…
Recent studies have shown that neutrophils, masts cells and eosinophils are able to release "extracellular traps" composed by chromatin filaments of nuclear DNA into the extracellular space, aggregated to enzymes and antimicrobial peptides. The extracellular traps have an important role in the innate immune response, with a powerful bactericidal effect. Several studies have demonstrated t…
(Only some records are available in English at this moment)
Chronic Rhinosinusitis (CRS) is defined as an inflammatory process of the nose and paranasal sinuses that persists for at least three consecutive months. Its pathophysiology remains unclear, and among the etiological factors involved, bacterial infection acts as either a modulating or exacerbating factor. Antibiotic therapy, considered a conservative treatment option, remains a controvers…
The demonstration of the presence of bacterial biofilms in patients with chronic rhinosinusitis has attracted great interest due to the resistance to antibiotics and the immune system. However, no studies that compare the values of minimum inhibitory concentration (MIC) of planktonic forms and biofilms of inhibitory concentration (BIC) obtained from patients with acute rhinosinusitis have…
In colonized niches, such as the gastrointestinal tract, commensal flora plays an important role in maintaining gastrointestinal homeostasis. However, little is known about the influence of commensal nasal flora on the pathogenesis of chronic inflammatory processes of the upper respiratory tract, such as chronic rhinosinusitis. A plausible hypothesis is that alterations in the resident fl…
| 5 / 5 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 4 / 2 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 11 / 9 | All research grants and scholarships |
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