bachelor's at Química com atribuição tecnológica from Universidade Federal do Rio de Janeiro (2001), master's at Chemistry from Universidade Federal do Rio de Janeiro (2002) and doctorate at Chemistry from Universidade Estadual de Campinas (2006). Has experience in Chemistry, focusing on Organic Synthesis, acting on the following subjects: grupamento acila, glicidóis and ditiana. (Source: Lattes Curriculum)
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This research project proposes to explore the formation of new C-C bonds using sulfoxonium ylides through four different reaction methods: epoxide opening, halogenation-arylation, addition reactions in electrophilic species derived from alkenes, and classical and photocatalytic radical reactions. (AU)
Alpha-Heterofunctionalized carbonyl compounds have a wide versatility as synthetic building blocks, due to a variety of transformations that these can participate. However, there are a limited number of asymmetric methodologies to prepare this class of compounds. Therefore, the development of such methodologies is of great importance in the area of organic synthesis. Combining this need w…
The expansion of products that can be obtained through the transformation of vegetal biomass has been a great challenge, especially in the case of complex molecules with high added value. In this case, it is important to develop new methodologies or synthetic transformations that can supply new compounds from raw materials that are easily obtained from the biomass in abundant form (levuli…
Subproject A: Synthesis of prochiral b-cetosulfoxonium ylides and its application in asymmetric insertion reactions catalyzed by gold. Subproject B: The use of Bronsted acids in the organocatalytic decomposition of diazo compounds in the presence of nucleophilic agents. (AU)
(Only some records are available in English at this moment)
Sulfur ylides consist of a chemical class that is currently establishing itself as versatile substrates in organic synthesis. Its structural characteristics guarantee an ambiphilic character, allowing sulfur ylides to participate in reactions with different electrophiles and nucleophiles.Although the ²-keto sulfoxonium ylides have a wide range of synthetic applications, one of the less ex…
Polyurethanes are polymeric materials that have a wide range of applications in various fields due to their attractive and diverse properties. The main production of these polymers occurs through the polyaddition reaction between diisocyanates and polyols. Polyols are important monomers that, in addition to their applications in the polyurethane industry, are also used, for example, as an…
A great challenge for synthetic organic chemists is ensuring molecular diversity and structural complexity in reaction products, carried out by selective methodologies with a few number of steps. The development of synthetic approaches that provide enantiomerically enriched compounds have attracted a continuous interest from both academia and industry, since different enantiomers of an or…
(Only some records are available in English at this moment)
This research project proposes to explore the reactivity of sulfur ylides with ketenes that are generated from diazocarbonyl compounds. This combination aims to obtain functionalized ³-butenolides and butyrolactams. At first, these transformations will be evaluated in the racemic fashion and later it will be extended to the asymmetric version. Currently, there are no reports in the litera…
The research proposed provides a unified catalytic strategy using chiral Brønsted acids to access carbon-oxygen, carbon-nitrogen, carbon-sulfur and carbon-halogen bonds from either diazoketones or sulfoxonium ylides as starting materials.
Alpha-heterofunctionalized carbonyl compounds have a wide versatility as synthetic building blocks, due to a variety of transformations that these can participate. However, there are a limited number of asymmetric methodologies to prepare this class of compounds. Therefore, the development of such methodologies is of great importance in the area of organic synthesis. Combining this need w…
(Only some records are available in English at this moment)
Our research group have been exploring the chemistry of sulfoxonium ylides and using these compounds in several relevant chemical transformations. Currently, we are studying the reactivity of these scaffold in the presence of diazo and hypervalent iodine. On this view, Prof. Dr. Graham Murphy at the University of Waterloo (Canada) has an extensive experience with hypervalent iodine reagen…
In recent years, sulfur ylides have received significant attention as equivalents of diazo compounds and as precursors of metal-carbene complexes. Although significative advances have been made regarding the use of a-carbonyl metal-carbenes as intermediates in organic synthesis, a less explored type of metal-carbene, containing a-imino group, still have limited sources and few general app…
Our research group have been exploring the chemistry of a,b-unsaturated diazoketones and b-ketosulfoxonium ylides and using these compounds in several relevant chemical transformations. Currently, we are studying enantioselective reactions employing a,b-unsaturated diazoketones, aryl and alkyl diazoketones and b-ketosulfoxonium ylides. In this project, enantioselective reactions will be d…
This project aims at applying the knowledge on the chemistry of alpha,beta-unsaturated diazoketones, developed in our group, to enable the site-selective modification of proteins in collaboration with Prof. Gonçalo Bernardes at University Of Cambridge, UK. Chemical protein modification has emerged as an invaluable tool for understanding natural systems, create therapeutic conjugates with …
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing research grants |
| 8 / 6 | Completed research grants |
| 5 / 5 | Ongoing scholarships in Brazil |
| 26 / 23 | Completed scholarships in Brazil |
| 1 / 1 | Ongoing scholarships abroad |
| 6 / 6 | Completed scholarships abroad |
| 47 / 42 | All research grants and scholarships |
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CV Lattes
ORCID