Kil Sun Lee in research grants and scholarships supported by FAPESP.
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Iron is an important micronutrient for many vital functions, and its bioavailability is closely related to the regulation of energy metabolism and cell survival or death. Data from the literature indicate that neglected iron deficiency can lead to impaired cardiac, endocrine and cognitive functions, among others. Therefore, under a pathological condition, detailed assessment of iron statu…
Scientific and technical advances in medicine and socioeconomic development contributed to the increase of life expectancy. On the other hand, aging of society has increased the prevalence of neurodegenerative diseases, while effective methods of treatment are not yet available. It is notable that the accumulation of protein aggregates is a common feature of many neurodegenerative disease…
The aging of modern society progressively increases the prevalence of neurodegenerative diseases, yet there is no cure. The accumulation of protein aggregates is a common feature of many neurodegenerative diseases and in most cases, protein aggregates occur without mutations in the gene or familiar or clinical history that explain the manifestation of the disease. This evidence corroborat…
(Only some records are available in English at this moment)
Sleep deprivation is a health problem that affects a huge proportion of Brazilian population, and is related to the development and worsening of many neurodegenerative disorders, such as Alzheimer's diseases, Parkinson's diseases and epilepsy. This relationship emerges from the dysregulation of sleep-wake cycle, which is supposed to be synchronized in every cell of the organism mainly by …
Obesity is a condition associated with unhealthy lifestyle habits, and is often accompanied by other chronic diseases such as cardiovascular disease and diabetes. With its incidence increasing and being a significant risk factor for several chronic non-communicable diseases, obesity has become one of the main public health problems. One of the comorbidities of obesity is iron deficiency…
Obesity is one of the biggest public health problems today because it affects a large part of the world's population and increase the risk of developing other diseases such as diabetes, cardiovascular disease and various types of cancer, among others. Various metabolic changes such as adipose tissue unhealthy expansion and remodeling, systemic inflammation, insulin resistance and increase…
Obesity is a metabolic syndrome whose development is mainly associated with environmental factors but is also influenced by genetic factors. Several comorbidities are associated with obesity, including iron deficiency which has been little investigated compared to other comorbidities. Iron deficiency in obesity can be established due to the endocrine activity of the adipose tissue. That w…
The aging interferes in diverse organic functions of the body with the capability to instigate diseases. Neurodegenerative diseases are an example that affects the elderly population. These diseases have a common feature in their pathological process, which is the deposition of protein aggregates. Protein aggregates can be formed spontaneously through the lifelong and their formation can …
Alzheimer's disease (AD) is a neurodegenerative disease triggered by several factors, including the accumulation of ²-amyloid peptides (pA²), which leads to loss of synapses and neurons. These peptides are generated from the proteolytic cleavage of the amyloid precursor protein (APP) and can modulate a neuronal activity. Subsequently, these peptides can be degraded in the brain or drained…
(Only some records are available in English at this moment)
| 6 / 4 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 12 / 9 | Completed scholarships in Brazil |
| 21 / 16 | All research grants and scholarships |
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