CV Lattes
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ORCID
Universidade Federal de São Carlos (UFSCAR). Centro de Ciências Exatas e de Tecnologia (CCET) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Quimica Industrial from Universidade Federal de Santa Maria (2003) and doctorate at Chemistry from Universidade Federal de Santa Maria (2007). Has experience in Chemistry, focusing on Organic Synthesis, acting on the following subjects: catálise assimétrica aminoácidos, asymmetric cataysis, stereoselective synthesis, selenium and zinc. (Source: Lattes Curriculum)
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In the last decades, the emphasis and application of sustainable chemistry principles have driven a change in behavior of both chemical industry and academy. They aim to obtain the desired product with fewest step, high yield and by using non-toxic reagents. In this context, the recognition of environmental benefits presented in photochemical reactions has motivated the scientific communi…
The long-term objective of this project is to contribute to the development of next generation ADCs as promising cancer therapeutics. We will prepare new conjugates for cancer therapy and imaging using a novel site-specific conjugation reaction for the conjugation of drugs and imaging probes to mAbs primarily in the IgG format (it can be extended to smaller recombinant formats). Ideally, …
The Centre of Excellence for Research in Sustainable Chemistry (CERSusChem) is an initiative of researchers at the Chemistry Department of the Federal University of São Carlos, aiming to promote the development and implementation of green and sustainable chemistry and related technologies. The Centre, is formed by 18 faculty members of 5 different Public Universities (UFSCar UNICAMP, USP-…
(Only some records are available in English at this moment)
The development of sustainable methodologies for the synthesis of biologic relevant molecules is of great importance for both academia (especially in organic synthesis and medicinal chemistry) and pharmaceutical industry. Thus, the use of visible light in synthesis of new compounds and systems with high degree of structural complexity has allowed the design of new methodologies. A special…
The compounds containing different functional groups are of considerable importance in the theoretical understanding of the transformations that lead to their synthesis and in the application of new molecules in synthetic organic chemistry. Interestingly, the chemical properties of each functional group can be changed through steric and electronic modifications, combined with the effects …
Since its inception, multicomponent reactions (MCRs) have positioned themselves as an important and powerful tool for the synthesis of compounds with potential biological activity. The great diversity and complexity, generated in a single reactional step, arouse great interest of the pharmaceutical industries. Among the multicomponent reactions, those that exploit the reactivity of isonit…
Pursuit for methodologies capable of construct molecular complexity in a fast, simple and sustainable ways has been a priority for synthetic chemists in recent years. Still, discovery of new compounds that have biological activity as well as other applications are of great interest to both academia and industry.It's well-known that molecules containing sulfonyl moieties show many applicat…
In the last decades, the emphasis and application of the green chemistry principles has driven a change of behavior in both fine chemical industry and academy - towards a more sustainable process - specially by looking for the obtention of desired product with a fewest number of steps, high yield and the use of non-toxic reagents. In this context, the increasing recognition of the environ…
In the last decades, the emphasis on applying the principles of Green Chemistry has been boosting the chemical industry and academia to change their behavior towards the application of a more sustainable chemistry. Having as a common goal, obtaining the desired product in as few steps as possible, high yield and the use of non-toxic reagents. In this context, the growing recognition of th…
(Only some records are available in English at this moment)
Acetals and hemiacetals are interesting building blocks for organic synthesis due to their easy preparation from alcohols and carbonyl compounds (both ubiquitous motifs in commercial and natural products). However, the first impressive application of these functional groups in organic synthesis came out just recently: acetals as substrates for photo-induced formylation reactions, through …
The proposed postdoctoral stage project consists in the development of strategies for dicarbofunctionalization of deactivated olefins using carbon dioxide and radical precursors. Initially, a nickel catalyzed redox strategy of trifluoromethylcarboxylation, using (2,2,2-trifluoroacetoxy) pyridinium trifluoroacetate as a precursor of the trifluoromethyl radical will be investigated. This st…
Common chemotherapeutic agents available in traditional anti-cancer treatments require administration at near the maximum tolerated dosage, lacking tumor selectivity and killing of proliferating normal cells. A recent class of therapy with considerable promise in the treatment of various cancers is the selective targeting of cytotoxic drugs to tumours by conjugating the drug to specific a…
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing research grants |
| 5 / 4 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 12 / 11 | Completed scholarships in Brazil |
| 4 / 4 | Completed scholarships abroad |
| 25 / 23 | All research grants and scholarships |
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