CV Lattes
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Ministério da Educação (Brasil). Universidade Federal do ABC (UFABC). Centro de Ciências Naturais e Humanas (CCNH) (Institutional affiliation for the last research proposal) Birthplace: Brazil
Graduated in Biomedicine at University of Santo Amaro (2001). She completed a Direct Doctorate (2006) and Post-Doctorate (2007) at the Department of Cell and Developmental Biology at the Institute of Biomedical Sciences at University of São Paulo. The research developed in this period, addressed the role of the Renin-Angiotensin System in the development of cardiac hypertrophy promoted by the thyroid hormone, as well as the actions of these hormones in the global modulation of gene expression. She is an Associate Professor at the Federal University of ABC developing a line of research on the impact of the inflammatory response and the immune system on cardiovascular changes observed in the context of Cardiorenal Syndrome. She has experience in the areas of cell biology, molecular biology, cardiovascular physiology, inflammation and renal failure. It has scientific projects funded by FAPESP and CNPq. Coordinates extension projects aimed at courses in ethics and research integrity for high school students from public schools. From 2012 to 2014 she was academic advisor to the UFABC Research Dean, becoming UFABC's Assistant Research Dean until early 2015. Between 2015 and 2018 she was Provost for research of UFABC. (Source: Lattes Curriculum)
Cardiorenal Syndrome is characterized by the presence of a systemic inflammatory condition where different clinical conditions promote cardiac and renal dysfunction. It has five different types where the first two (types 1 and 2) are associated with abnormalities in cardiac function that cause injury or renal dysfunction; the type 3 and 4 that are characterized by renal insults that subje…
The immune system interacts with several different tissues and organs of the human body, for example, the heart tissue. In diseases that generate a systemic inflammation, some factors are released in the blood stream and they are able to reach the most diverse organs, promoting interaction between tissue cells and immunity cells. It is known that renal insufficiency (RI) is characterized …
Cardiac remodeling occurs primarily as an adaptive response to an increase in demand, commonly resulting in the so called cardiac hypertrophy. The heart is a target organ in many regulatory systems, such as hormones, neuronal and hemodynamic factors, which modulate heart trophism direct or indirectly. Besides these actions, largely described in the literature, it is well known the heart i…
Cardiovascular disease (CVD) is the main cause of mortality in patients undergoing hemodialysis and represents 45% of deaths. Left ventricular hypertrophy (LVH) is a common pattern of cardiovascular injury in chronic kidney disease that affects up to 75% of individuals when it affects end-stage renal disease. In addition, renal ischemia/reperfusion (I/R) is the major cause of acute kidney…
In diseases that generate an inflammatory situation, such as Cardiorenal Syndrome, different clinical conditions promote cardiac and renal dysfunction. It has five different types and the first two (types 1 and 2) are associated anormalities in cardiac function that cause injury or renal dysfunction; type 3 and 4 are characterized by renal insults that subject the heart to dysfunctions; t…
Cardiovascular diseases (CVD) are the cause of much of the deaths, due not only to genetic factors, but also to environmental factors, due to the modern way of life. However, they may be secondary to other diseases, such as cardiorenal syndromes (SCRs). Cardiorenal syndromes are diseases that show the intense connection between the functioning of the kidneys and the heart and are subdivid…
Patients with chronic renal ischemia have a high risk to develop cardiovascular diseases. These diseases represent a 41% of death in patient in hemodialysis treatment. Therefore, understand the physiopathological mechanisms involved is critical. Recently, a study conducted by the proponent of the present project showed an elevated concentration of IL-1² 8 days after renal ischemia-reper…
The immune system presents different interfaces among systems and other body tissues, such as heart tissue. In diseases that generate inflammatory condition, the factors released into the bloodstream can reach many more organs, promoting interaction between tissue cells and immune components. It is known that renal insufficiency (RI) is characterized by a systemic inflammatory condition a…
(Only some records are available in English at this moment)
The Cardiorenal Syndrome is characterized by the presence of a systemic inflammatory condition where different clinical conditions promote cardiac and renal dysfunction. It has five different types where the first two types (type 1 and 2) are associated with abnormalities in cardiac function that cause injury or renal dysfunction; those of type 3 and 4 that are characterized by renal insu…
| 2 / 1 | Ongoing research grants |
| 6 / 3 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 10 / 6 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 21 / 13 | All research grants and scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 7 |
| Citations | 2 |
| Cit./Article | 0.3 |
| Data from Web of Science | |
CRUZ JUNHO, V, C.; TRENTIN-SONODA, M.; ALVIM, J. M.; GAISLER-SILVA, F.; CARNEIRO-RAMOS, M. S.. Ca(2+/)Calmodulin-dependent kinase II delta B is essential for cardiomyocyte hypertrophy and complement gene expression after LPS and HSP60 stimulation in vitro. Brazilian Journal of Medical and Biological Research, v. 52, n. 7, 2019. Web of Science Citations: 1. (15/01792-3, 16/11865-0, 15/19107-5, 14/16908-4)
TRENTIN-SONODA, MAYRA; FRATONI, FRAYLI MALTONI; DA CRUZ JUNHO, CAROLINA VICTORIA; SILVA, WELLINGTON CAIO; PANICO, KARINE; CARNEIRO-RAMOS, MARCELA SORELLI. Caspase-1 as Molecular Key in Cardiac Remodeling during Cardiorenal Syndrome Type 3 in the Murine Model. CURRENT MOLECULAR MEDICINE, v. 20, n. 1, p. 72-78, 2020. Web of Science Citations: 0. (15/15832-7, 15/19107-5)
PIERETTI, JOANA CLAUDIO; CRUZ JUNHO, CAROLINA VICTORIA; CARNEIRO-RAMOS, MARCELA SORELLI; SEABRA, AMEDEA BAROZZI. H2S- and NO-releasing gasotransmitter platform: A crosstalk signaling pathway in the treatment of acute kidney injury. PHARMACOLOGICAL RESEARCH, v. 161, NOV 2020. Web of Science Citations: 0. (18/02832-7, 18/03089-6, 18/08194-2, 15/19107-5)
JUNHO, CAROLINA VICTORIA CRUZ; CAIO-SILVA, WELLINGTON; TRENTIN-SONODA, MAYRA; CARNEIRO-RAMOS, MARCELA SORELLI. An Overview of the Role of Calcium/Calmodulin-Dependent Protein Kinase in Cardiorenal Syndrome. FRONTIERS IN PHYSIOLOGY, v. 11, JUL 14 2020. Web of Science Citations: 0. (08/10175-4, 14/16908-4)
C.V. CRUZ JUNHO; M. TRENTIN-SONODA; J.M. ALVIM; F. GAISLER-SILVA; M.S. CARNEIRO-RAMOS. Ca2+/Calmodulin-dependent kinase II delta B is essential for cardiomyocyte hypertrophy and complement gene expression after LPS and HSP60 stimulation in vitro. Brazilian Journal of Medical and Biological Research, v. 52, n. 7, p. -, 2019. (16/11865-0, 15/01792-3, 14/16908-4, 15/19107-5)
CIRINO-SILVA, ROGERIO; KMIT, FERNANDA V.; TRENTIN-SONODA, MAYRA; NAKAMA, KARINA K.; PANICO, KARINE; ALVIM, JULIANA M.; DREYER, THIAGO R.; MARTINHO-SILVA, HERCULANO; CARNEIRO-RAMOS, MARCELA S.. Renal ischemia/reperfusion-induced cardiac hypertrophy in mice: Cardiac morphological and morphometric characterization. JRSM CARDIOVASCULAR DISEASE, v. 6, JAN 1 2017. Web of Science Citations: 0. (15/19107-5)
LOPEZ ALARCON, MARIA MICAELA; TRENTIN-SONODA, MAYRA; PANICO, KARINE; SCHLEIER, YGOR; DUQUE, THABATA; MORENO-LOAIZA, OSCAR; DE YURRE, AINHOA RODRIGUEZ; FERREIRA, FABIANNO; CAIO-SILVA, WELLINGTON; COURY, PEDROSA ROBERTO; et al. Cardiac arrhythmias after renal I/R depend on IL-1 beta. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, v. 131, p. 101-111, JUN 2019. Web of Science Citations: 1. (17/05974-4, 08/10175-4)
CARNEIRO-RAMOS‚ MS; SILVA‚ VB; SANTOS‚ RAS; BARRETO-CHAVES‚ MLM. Tissue-specific modulation of angiotensin-converting enzyme (ACE) in hyperthyroidism. Peptides, v. 27, n. 11, p. 2942-2949, 2006.
CAIO-SILVA, WELLINGTON; DA SILVA DIAS, DANIELLE; JUNHO, CAROLINA VICTORIA CRUZ; PANICO, KARINE; NERES-SANTOS, RAQUEL SILVA; PELEGRINO, MILENA TREVISAN; PIERETTI, JOANA CLAUDIO; SEABRA, AMEDEA BAROZZI; DE ANGELIS, KATIA; CARNEIRO-RAMOS, MARCELA SORELLI. Characterization of the Oxidative Stress in Renal Ischemia/Reperfusion-Induced Cardiorenal Syndrome Type 3. BIOMED RESEARCH INTERNATIONAL, v. 2020, OCT 9 2020. Web of Science Citations: 0. (18/02832-7, 18/08194-2, 08/10175-4, 17/05029-8, 19/11077-0)