Fábio Márcio Squina
CV Lattes
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Universidade de Sorocaba (UNISO). Pró-Reitoria de Pós-Graduação, Pesquisa, Extensão e Inovação (Institutional affiliation for the last research proposal) Birthplace: Brazil
Dr Fabio Squina is Pharmacist, MS in Food Science and Ph.D. in Molecular and Cell Biology. He has the background on Biochemistry, Molecular Biology and Omics Sciences. Currently, he serves as adjunct professor position at UNISO (http://pta.uniso.br/), and academic advisor appointments at UNICAMP . 

Fabio Squinas scientific interests focus on biocatalyst discovery and development of biotechnological routes for lignocellulose conversion into high value products. Dr Fabio Squinas research group has made contributions on metagenomics-based enzyme discovery field, establishing discovery platform, based on targeted community enrichment protocols and 'Omics' approaches. FSs group has also successfully engagement on the development of enzymatic routes for the production of natural probiotics, phenolic compounds, and antioxidant molecules. These biotechnological initiatives are aligned to bio-refinery interests based on the potential of adding value to lignocellulose, such as sugarcane bagasse. 

Dr. Squina received the prestigious Young Investigator Award from São Paulo Research Foundation (FAPESP) on 2009. From 2013 to 2017, Dr. Squina coordinated Industrial Innovation project with Eli Lilly Brazil as co-Financier. Since July 2017, Dr. Squina coordinates FAPESP thematic grant entitled: Lignin valorization in cellulosic ethanol plants: biocatalytic conversion via ferulic acid to high-value chemicals. Dr. Squina has published more than a hundred papers and disclosed eight certificates of patents. (Source: Lattes Curriculum)
| News published in Agência FAPESP Newsletter about the researcher |
| Novel biotechnological route developed to obtain fine chemicals from agricultural waste |
| Joint FAPESP-BBSRC Collaborative Project Meeting |
| Articles published in Pesquisa para Inovação FAPESP about the researcher: |
| Novel biotechnological route developed to obtain fine chemicals from agricultural waste |
| Novel biotechnological route developed to obtain fine chemicals from agricultural waste |
- Lignin valorization in cellulosic ethanol plants: biocatalytic conversion via feluric acid to high value chemicals, AP.BIOEN.TEM
Abstract
Lignin can be obtained as a by-product of cellulosic ethanol production, and is a potential source of renewable chemicals, if methods for lignin valorization can be developed. Efficient valorisation of lignin is a major unsolved problem in the development of sustainable biorefineries. The proposal builds upon an existing BBSRC partnership award, and brings together expertise in biocatal...
- Expanding the knowledge on lignocellulolytic and redox enzymes of worker and soldier castes from the lower termite Coptotermes gestroi, PUB.ART
Abstract
Termites are considered one of the most efficient decomposers of lignocelluloses on Earth due to their ability to produce, along with its microbial symbionts, a repertoire of carbohydrate-active enzymes (CAZymes). Recently, a set of Pro-oxidant, Antioxidant, and Detoxification enzymes (PAD) were also correlated with the metabolism of carbohydrates and lignin in termites. The lower termi...
- Second Generation Bioethanol 2014, AO.R
- Integrated enzyme discovery and pathway optimization for bagase valorization, AP.BIOEN.R
Abstract
The ultimate aims of this project are i) to utilize a microbial metagenomics platform to enable novel enzyme building block discovery and identification, ii) to assess the capabilities and of the bacteriallignin peroxidase treatment against sugarcane bagasse lignin, iii) to integrate these building blocks into suitably engineered host chassis using synthetic biology principies and to en...
(Only some records are available in English at this moment)
- Bioprocesses intensification, expansion of chemical products production and lignocellulose processing, BP.TT
- Conversion of lignin to ferulic acid (WP2), BP.TT
- Development of the CRISPR/Cas9 system in Rhodococcus jostii RHA1 for production of high-value chemicals from lignin streams, BP.DD
Abstract
In the context of lignin valorization, the use of whole-cell biocatalysts for deconstruction and conversion of lignin is a promising alternative to chemical catalysis that could render more cost-effective and environmentally-friendly results. The species Rhodococcus jostii RHA1 is of particular biotechnological interest due to its ability to catabolize a wide array of aromatic compounds...
(Only some records are available in English at this moment)
- WP3: biocatalytic formation of fragrance chemicals from ferulic acid, BP.TT
- Development of E. coli-Rhodococcus CRISPR/Cas9 shuttle vector targeting ferulic acid accumulating Rhodococcus jostii RHA1 mutants, BP.MS
Abstract
Lignocellulosic biomass is a cheap and abundant resource which arises as an attractive alternative to oil for conversion into fuels and chemicals. Up to a third of lignocellulosic biomass is composed of lignin, a highly recalcitrant aromatic polymer, which is disposed as waste or burned for power in biomass processing biorefineries and pulp/paper industries. These streams represent an ...
- Influence of an accessory domain in biochemical and structural characteristics of the cellulase CelE2, BP.MS
Abstract
Different physicochemical and enzymatic treatments are applied in order to overcome the recalcitrance of plant cell wall to degradation. Glycosyl hydrolases (GHs) integrate a class of enzymes widely used in enzymatic process since they perform the hydrolysis of glycosidic bonds in a wide variety of polysaccharides. Apart from the catalytic domains, several glycosyl hydrolases contain ac...
(Only some records are available in English at this moment)
- Cellulosomes - a versatile enzymatic scaffold platform for bioconversion of lignocellulosic biomass into value-added fine chemicals, BE.EP.PD
Abstract
Lignocellulosic biomass is a renewable and sustainable resource for production of fuels and value-added chemicals. In this context, we have devised an experimental approach to combine lignocellulosic biomass breakdown with direct conversion of the released monomers into fine chemicals. We hypothesize that by mimicking natural cellulosomes, we could design a mini-cellulosome, which will ...
- Development of a synthetic route to produce coniferyl alcohol from ferulic acid using an Aldo-Keto Reductase from lower termite Coptotermes gestroi, BE.EP.DR
Abstract
The use of enzymes and cell-based systems is an excellent alternative to traditional chemical processes, since it can be environmentally cleaner, faster and more cost-effective. Termites are considered an excellent biological system for studying biochemical conversion of lignocellulosic biomass, because not only carbohydrate-active enzymes (CAZymes), such as cellulases, are found in the...
- The structure and function of three multimodular glycoside hydrolases related to cellulose, hemicellulose and pectin breakdown, and the influence of the accessory modules in the catalytic activity, BE.EP.PD
Abstract
Glycoside hydrolases (GH) are enzymes able to cleave the glycosidic bonds of different types of carbohydrates found in nature. Thanks to their activity, they became a research target in the production of second-generation ethanol. In this process, the fermentable sugars come from the breakdown of the polysaccharides present in the cell wall of plants. Since these polysaccharides form an...
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing research grants |
| 8 / 6 | Completed research grants |
| 8 / 8 | Ongoing scholarships in Brazil |
| 17 / 15 | Completed scholarships in Brazil |
| 7 / 7 | Completed scholarships abroad |
| 41 / 37 | All research grants and scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 56 |
| Citations | 765 |
| Cit./Article | 13.7 |
| Data from Web of Science | |
SEGATO, FERNANDO; DAMASIO, ANDRE R. L.; DE LUCAS, ROSYMAR C.; SQUINA, FABIO M.; PRADE, ROLF A.. Genomics Review of Holocellulose Deconstruction by Aspergilli. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, v. 78, n. 4, p. 588-613, DEC 2014. Web of Science Citations: 33. (13/18910-3, 12/20549-4, 08/58037-9, 10/18198-3)
TRAMONTINA, ROBSON; FRANCO CAIRO, JOAO PAULO L.; LIBERATO, MARCELO V.; MANDELLI, FERNANDA; SOUSA, AMANDA; SANTOS, SAMANTHA; RABELO, SARITA CANDIDA; CAMPOS, BRUNA; IENCZAK, JACIANE; RULLER, ROBERTO; et al. The Coptotermes gestroi aldo-keto reductase: a multipurpose enzyme for biorefinery applications. BIOTECHNOLOGY FOR BIOFUELS, v. 10, JAN 3 2017. Web of Science Citations: 6. (13/06336-0, 12/20549-4, 14/20576-7, 14/04105-4, 08/58037-9)
ALVAREZ, THABATA M.; GOLDBECK, ROSANA; DOS SANTOS, CAMILA RAMOS; PAIXAO, DOUGLAS A. A.; GONCALVES, THIAGO A.; FRANCO CAIRO, JOAO PAULO L.; ALMEIDA, RODRIGO FERREIRA; PEREIRA, ISABELA DE OLIVEIRA; JACKSON, GEORGE; COTA, JUNIO; et al. Development and Biotechnological Application of a Novel Endoxylanase Family GH10 Identified from Sugarcane Soil Metagenome. PLoS One, v. 8, n. 7, JUL 29 2013. Web of Science Citations: 12. (11/20977-3, 10/11469-1, 08/58037-9)
TRAMONTINA, ROBSON; BRENELLI, LIVIA BEATRIZ; SOUSA, AMANDA; ALVES, RAFAEL; ZETTY ARENAS, ANA MARIA; NASCIMENTO, VIVIANE MARCOS; RABELO, SARITA CANDIDA; FREITAS, SINDELIA; RULLER, ROBERTO; SQUINA, FABIO MARCIO. Designing a cocktail containing redox enzymes to improve hemicellulosic hydrolysate fermentability by microorganisms. Enzyme and Microbial Technology, v. 135, APR 2020. Web of Science Citations: 0. (15/50590-4, 13/03061-0, 17/15477-8, 15/26982-0, 16/07926-4)
BRENELLI, LIVIA B.; PERSINOTI, GABRIELA F.; FRANCO CAIRO, JOAO PAULO L.; LIBERATO, MARCELO V.; GONCALVES, THIAGO AUGUSTO; OTERO, IGOR V. R.; MAINARDI, PEDRO H.; FELBY, CLAUS; SETTE, LARA D.; SQUINA, FABIO M.. Novel redox-active enzymes for ligninolytic applications revealed from multiomics analyses of Peniophora sp. CBMAI 1063, a laccase hyper-producer strain. SCIENTIFIC REPORTS, v. 9, NOV 26 2019. Web of Science Citations: 0. (13/03061-0, 13/19486-0, 15/07008-2, 14/04105-4, 16/09950-0, 15/06971-3, 15/50590-4, 17/16089-1)
DE SOUZA, WAGNER R.; MARTINS, POLYANA K.; FREEMAN, JACKIE; PELLNY, TILL K.; MICHAELSON, LOUISE V.; SAMPAIO, BRUNO L.; VINECKY, FELIPE; RIBEIRO, ANA P.; DA CUNHA, BARBARA A. D. B.; KOBAYASHI, ADILSON K.; et al. Suppression of a single BAHD gene in Setaria viridis causes large, stable decreases in cell wall feruloylation and increases biomass digestibility. NEW PHYTOLOGIST, v. 218, n. 1, p. 81-93, APR 2018. Web of Science Citations: 19. (16/07926-4)
MAINARDI, PEDRO H.; FEITOSA, VALKER A.; BRENELLI DE PAIVA, LIVIA B.; BONUGLI-SANTOS, RAFAELLA C.; SQUINA, FABIO M.; PESSOA, JR., ADALBERTO; SETTE, LARA D.. Laccase production in bioreactor scale under saline condition by the marine-derived basidiomycete Peniophora sp CBMAI 1063. FUNGAL BIOLOGY, v. 122, n. 5, p. 302-309, MAY 2018. Web of Science Citations: 8. (13/03061-0, 13/12505-0, 13/19486-0, 16/07957-7, 14/06923-6)
GRANJA-TRAVEZ, ROMMEL SANTIAGO; WILKINSON, RACHAEL C.; PERSINOTI, GABRIELA FELIX; SQUINA, FABIO M.; FULOP, VILMOS; BUGG, TIMOTHY D. H.. Structural and functional characterisation of multi-copper oxidase CueO from lignin-degrading bacterium Ochrobactrum sp reveal its activity towards lignin model compounds and lignosulfonate. FEBS Journal, v. 285, n. 9, p. 1684-1700, MAY 2018. Web of Science Citations: 8. (15/50590-4)
DIAS, FABRICIO C.; RUIZ, JERONIMO C.; LOPES, WILTON C. Z.; SQUINA, FABIO M.; RENZI, ADRIANA; CRUZ, ANGELA K.; TOSI, LUIZ R. O.. Organization of H locus conserved repeats in Leishmania (Viannia) braziliensis correlates with lack of gene amplification and drug resistance. Parasitology Research, v. 101, n. 3, p. 667-676, Aug. 2007.
SEGATO, FERNANDO; DAMASIO, ANDRE R. L.; GONCALVES, THIAGO A.; DE LUCAS, ROSYMAR C.; SQUINA, FABIO M.; DECKER, STEPHEN R.; PRADE, ROLF A.. High-yield secretion of multiple client proteins in Aspergillus. Enzyme and Microbial Technology, v. 51, n. 2, p. 100-106, JUL 15 2012. Web of Science Citations: 37. (10/18198-3)
SQUINA‚ F. M.; PEDROSA‚ A. L.; NUNES‚ V. S.; CRUZ‚ A. K.; TOSI‚ L. R. O.. Shuttle mutagenesis and targeted disruption of a telomere-located essential gene of Leishmania. Parasitology, v. 134, n. 04, p. 511-522, Apr. 2007. (99/12403-3)
DA SILVA, VIVIAM M.; CABRAL, ALINE D.; SPERANCA, MARCIA A.; SQUINA, FABIO M.; MUNIZ, JOAO RENATO C.; MARTIN, LYDIE; NICOLET, YVAIN; GARCIA, WANIUS. High-resolution structure of a modular hyperthermostable endo-beta-1,4-mannanase from Thermotoga petrophila: The ancillary immunoglobulin-like module is a thermostabilizing domain. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, v. 1868, n. 8, AUG 2020. Web of Science Citations: 0. (13/26096-4, 16/15836-5, 17/17275-3, 17/16291-5, 14/02065-5, 16/14514-4, 14/50897-0, 15/50590-4)
FRANCO CAIRO, JOAO PAULO L.; LEONARDO, FLAVIA C.; ALVAREZ, THABATA M.; RIBEIRO, DANIELA A.; BUECHLI, FERNANDA; COSTA-LEONARDO, ANA M.; CARAZZOLLE, MARCELO F.; COSTA, FERNANDO F.; PAES LEME, ADRIANA F.; PEREIRA, GONCALO A. G.; et al. Functional characterization and target discovery of glycoside hydrolases from the digestome of the lower termite Coptotermes gestroi. BIOTECHNOLOGY FOR BIOFUELS, v. 4, NOV 14 2011. Web of Science Citations: 23. (10/11469-1, 08/58037-9)
DIOGO, JOSE A.; HOFFMAM, ZAIRA B.; ZANPHORLIN, LETICIA M.; COTA, JUNIO; MACHADO, CARLA B.; WOLF, LUCIA D.; SQUINA, FABIO; DAMASIO, ANDRE R. L.; MURAKAMI, MARIO T.; RULLER, ROBERTO. Development of a chimeric hemicellulase to enhance the xylose production and thermotolerance. Enzyme and Microbial Technology, v. 69, p. 31-37, FEB 2015. Web of Science Citations: 10. (13/10443-7, 08/58037-9, 11/14200-6)
DAMASIO, ANDRE R. L.; RUBIO, MARCELO V.; OLIVEIRA, LEANDRO C.; SEGATO, FERNANDO; DIAS, BRUNO A.; CITADINI, ANA P.; PAIXAO, DOUGLAS A.; SQUINA, FABIO M.. Understanding the Function of Conserved Variations in the Catalytic Loops of Fungal Glycoside Hydrolase Family 12. Biotechnology and Bioengineering, v. 111, n. 8, p. 1494-1505, AUG 2014. Web of Science Citations: 12. (11/13242-7, 12/12859-3, 08/58037-9)
BORIN, GUSTAVO PAGOTTO; SANCHEZ, CAMILA CRISTINA; DE SOUZA, AMANDA PEREIRA; DE SANTANA, ELIANE SILVA; DE SOUZA, ALINE TIEPPO; PAES LEME, ADRIANA FRANCO; SQUINA, FABIO MARCIO; BUCKERIDGE, MARCOS; GOLDMAN, GUSTAVO HENRIQUE; DE CASTRO OLIVEIRA, JULIANA VELASCO. Comparative Secretome Analysis of Trichoderma reesei and Aspergillus niger during Growth on Sugarcane Biomass. PLoS One, v. 10, n. 6, JUN 8 2015. Web of Science Citations: 38. (13/01071-9, 13/09541-4, 11/08945-9)
GOLDBECK, ROSANA; DAMASIO, ANDRE R. L.; GONCALVES, THIAGO A.; MACHADO, CARLA B.; PAIXAO, DOUGLAS A. A.; WOLF, LUCIA D.; MANDELLI, FERNANDA; ROCHA, GEORGE J. M.; RULLER, ROBERTO; SQUINA, FABIO M.. Development of hemicellulolytic enzyme mixtures for plant biomass deconstruction on target biotechnological applications. Applied Microbiology and Biotechnology, v. 98, n. 20, p. 8513-8525, OCT 2014. Web of Science Citations: 23. (13/18910-3, 08/58037-9, 12/18859-5)
CAMPOS, BRUNA MEDEIA; LIBERATO, MARCELO VIZONA; ALVAREZ, THABATA MARIA; ZANPHORLIN, LETICIA MARIA; EMATSU, GABRIELA CRISTINA; BARUD, HERNANE; POLIKARPOV, IGOR; RULLER, ROBERTO; GILBERT, HARRY J.; DE MATTOS ZERI, ANA CAROLINA; et al. A Novel Carbohydrate-binding Module from Sugar Cane Soil Metagenome Featuring Unique Structural and Carbohydrate Affinity Properties. Journal of Biological Chemistry, v. 291, n. 45, p. 23734-23743, NOV 4 2016. Web of Science Citations: 5. (13/06336-0, 14/04105-4, 08/58037-9, 10/11469-1)
MANDELLI, F.; COUGER, M. B.; PAIXAO, D. A. A.; MACHADO, C. B.; CARNIELLI, C. M.; ARICETTI, J. A.; POLIKARPOV, I.; PRADE, R.; CALDANA, C.; PAES LEME, A. F.; et al. Thermal adaptation strategies of the extremophile bacterium Thermus filiformis based on multi-omics analysis. EXTREMOPHILES, v. 21, n. 4, p. 775-788, JUL 2017. Web of Science Citations: 7. (10/18198-3)
PELLEGRINI, VANESSA O. A.; SERPA, VIVIANE ISABEL; GODOY, ANDRE S.; CAMILO, CESAR M.; BERNARDES, AMANDA; REZENDE, CAMILA A.; PEREIRA JUNIOR, NEI; CAIRO, JOAO PAULO L. FRANCO; SQUINA, FABIO M.; POLIKARPOV, IGOR. Recombinant Trichoderma harzianum endoglucanase I (Cel7B) is a highly acidic and promiscuous carbohydrate-active enzyme. Applied Microbiology and Biotechnology, v. 99, n. 22, p. 9591-9604, NOV 2015. Web of Science Citations: 11. (11/20977-3, 09/05328-9, 08/56255-9, 10/18773-8, 09/52840-7, 11/05712-3)
TRAMONTINA, ROBSON; GALMAN, JAMES L.; PARMEGGIANI, FABIO; DERRINGTON, SASHA R.; BUGG, TIMOTHY D. H.; TURNER, NICHOLAS J.; SQUINA, FABIO M.; DIXON, NEIL. Consolidated production of coniferol and other high-value aromatic alcohols directly from lignocellulosic biomass. GREEN CHEMISTRY, v. 22, n. 1, p. 144-152, JAN 7 2020. Web of Science Citations: 0. (15/50590-4, 17/23754-1)
VELASCO, JOSMAN; OLIVA, BIANCA; GONCALVES, ALINE LARISSA; LIMA, AWANA SILVA; FERREIRA, GISLENE; FRANCA, BRUNO ALVES; MULINARI, EVANDRO JOSE; GONCALVES, THIAGO AUGUSTO; SQUINA, FABIO MARCIO; SEIKI KADOWAKI, MARCO ANTONIO; et al. Functional characterization of a novel thermophilic exo-arabinanase fromThermothielavioides terrestris. Applied Microbiology and Biotechnology, v. 104, n. 19, AUG 2020. Web of Science Citations: 0. (14/18714-2, 17/16089-1, 14/06923-6, 19/01165-0, 15/50590-4, 19/06663-8)
TOMAZETTO, GEIZECLER; PIMENTEL, AGNES C.; WIBBERG, DANIEL; DIXON, NEIL; SQUINA, FABIO M.. Multi-omic Directed Discovery of Cellulosomes, Polysaccharide Utilization Loci, and Lignocellulases from an Enriched Rumen Anaerobic Consortium. Applied and Environmental Microbiology, v. 86, n. 18, SEP 2020. Web of Science Citations: 0. (15/23279-6, 15/50590-4, 18/23826-5, 16/01926-2)
PUHL, ANA C.; PRATES, ERICA T.; ROSSETO, FLAVIO R.; MANZINE, LIVIA R.; STANKOVIC, IVANA; DE ARAUJO, SIMARA S.; ALVAREZ, THABATA M.; SQUINA, FABIO M.; SKAF, MUNIR S.; POLIKARPOV, IGOR. Crystallographic structure and molecular dynamics simulations of the major endoglucanase from Xanthomonas campestris pv. campestris shed light on its oligosaccharide products release pattern. International Journal of Biological Macromolecules, v. 136, p. 493-502, SEP 1 2019. Web of Science Citations: 0. (11/20505-4, 15/13684-0, 09/52840-7, 10/52362-5, 11/21608-1, 15/50590-4)
VALADARES, FERNANDA; GONCALVES, THIAGO A.; DAMASIO, ANDRE; MILAGRES, ADRIANE M. F.; SQUINA, FABIO M.; SEGATO, FERNANDO; FERRAZ, ANDRE. The secretome of two representative lignocellulose-decay basidiomycetes growing on sugarcane bagasse solid-state cultures. Enzyme and Microbial Technology, v. 130, NOV 2019. Web of Science Citations: 0. (17/16089-1, 15/50590-4, 14/06923-6)
AUGUSTO‚ M. J.; SQUINA‚ F. M.; MARCHINI‚ J. F. M.; DIAS‚ F. C.; TOSI‚ L. R. O.. Specificity of modified Drosophila mariner transposons in the identification of Leishmania genes. Experimental Parasitology, v. 108, n. 3-4, p. 109-113, 2004.
SEGATO, FERNANDO; DAMASIO, ANDRE R. L.; DE LUCAS, ROSYMAR C.; SQUINA, FABIO M.; PRADE, ROLF A.. Genomics Review of Holocellulose Deconstruction by Aspergilli. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, v. 78, n. 4, p. 588-613, DEC 2014. Web of Science Citations: 33. (13/18910-3, 12/20549-4, 08/58037-9, 10/18198-3)
TRAMONTINA, ROBSON; FRANCO CAIRO, JOAO PAULO L.; LIBERATO, MARCELO V.; MANDELLI, FERNANDA; SOUSA, AMANDA; SANTOS, SAMANTHA; RABELO, SARITA CANDIDA; CAMPOS, BRUNA; IENCZAK, JACIANE; RULLER, ROBERTO; et al. The Coptotermes gestroi aldo-keto reductase: a multipurpose enzyme for biorefinery applications. BIOTECHNOLOGY FOR BIOFUELS, v. 10, JAN 3 2017. Web of Science Citations: 6. (13/06336-0, 12/20549-4, 14/20576-7, 14/04105-4, 08/58037-9)
ALVAREZ, THABATA M.; GOLDBECK, ROSANA; DOS SANTOS, CAMILA RAMOS; PAIXAO, DOUGLAS A. A.; GONCALVES, THIAGO A.; FRANCO CAIRO, JOAO PAULO L.; ALMEIDA, RODRIGO FERREIRA; PEREIRA, ISABELA DE OLIVEIRA; JACKSON, GEORGE; COTA, JUNIO; et al. Development and Biotechnological Application of a Novel Endoxylanase Family GH10 Identified from Sugarcane Soil Metagenome. PLoS One, v. 8, n. 7, JUL 29 2013. Web of Science Citations: 12. (11/20977-3, 10/11469-1, 08/58037-9)
TRAMONTINA, ROBSON; BRENELLI, LIVIA BEATRIZ; SOUSA, AMANDA; ALVES, RAFAEL; ZETTY ARENAS, ANA MARIA; NASCIMENTO, VIVIANE MARCOS; RABELO, SARITA CANDIDA; FREITAS, SINDELIA; RULLER, ROBERTO; SQUINA, FABIO MARCIO. Designing a cocktail containing redox enzymes to improve hemicellulosic hydrolysate fermentability by microorganisms. Enzyme and Microbial Technology, v. 135, APR 2020. Web of Science Citations: 0. (15/50590-4, 13/03061-0, 17/15477-8, 15/26982-0, 16/07926-4)
DIAS, FABRICIO C.; RUIZ, JERONIMO C.; LOPES, WILTON C. Z.; SQUINA, FABIO M.; RENZI, ADRIANA; CRUZ, ANGELA K.; TOSI, LUIZ R. O.. Organization of H locus conserved repeats in Leishmania (Viannia) braziliensis correlates with lack of gene amplification and drug resistance. Parasitology Research, v. 101, n. 3, p. 667-676, Aug. 2007.
SEGATO, FERNANDO; DAMASIO, ANDRE R. L.; GONCALVES, THIAGO A.; DE LUCAS, ROSYMAR C.; SQUINA, FABIO M.; DECKER, STEPHEN R.; PRADE, ROLF A.. High-yield secretion of multiple client proteins in Aspergillus. Enzyme and Microbial Technology, v. 51, n. 2, p. 100-106, JUL 15 2012. Web of Science Citations: 37. (10/18198-3)
DA SILVA, VIVIAM M.; CABRAL, ALINE D.; SPERANCA, MARCIA A.; SQUINA, FABIO M.; MUNIZ, JOAO RENATO C.; MARTIN, LYDIE; NICOLET, YVAIN; GARCIA, WANIUS. High-resolution structure of a modular hyperthermostable endo-beta-1,4-mannanase from Thermotoga petrophila: The ancillary immunoglobulin-like module is a thermostabilizing domain. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, v. 1868, n. 8, AUG 2020. Web of Science Citations: 0. (13/26096-4, 16/15836-5, 17/17275-3, 17/16291-5, 14/02065-5, 16/14514-4, 14/50897-0, 15/50590-4)
SEGATO, FERNANDO; DAMASIO, ANDRE R. L.; GONCALVES, THIAGO AUGUSTO; MURAKAMI, MARIO T.; SQUINA, FABIO M.; POLIZELI, MARIA DE LOURDES T. M.; MORT, ANDREW J.; PRADE, ROLF A.. Two structurally discrete GH7-cellobiohydrolases compete for the same cellulosic substrate fiber. BIOTECHNOLOGY FOR BIOFUELS, v. 5, APR 11 2012. Web of Science Citations: 12. (10/18198-3)
SQUINA, FABIO MARCIO; PRADE, ROLF ALEXANDER; WANG, HONGLIANG; MURAKAMI, MARIO TYAGO. Expression, purification, crystallization and preliminary crystallographic analysis of an endo-1,5-alpha-L-arabinanase from hyperthermophilic Thermotoga petrophila. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, v. 65, n. 9, p. 902-905, Aug. 2009. Web of Science Citations: 8. (08/58037-9)
GONCALVES, T. A.; DAMASIO, A. R. L.; SEGATO, F.; ALVAREZ, T. M.; BRAGATTO, J.; BRENELLI, L. B.; CITADINI, A. P. S.; MURAKAMI, M. T.; RULLER, R.; PAES LEME, A. F.; et al. Functional characterization and synergic action of fungal xylanase and arabinofuranosidase for production of xylooligosaccharides. Bioresource Technology, v. 119, p. 293-299, SEP 2012. Web of Science Citations: 40. (11/02169-7, 10/11469-1, 10/18198-3)
PERSINOTI, GABRIELA F.; PAIXAO, DOUGLAS A. A.; BUGG, TIMOTHY D. H.; SQUINA, FABIO M.. Genome Sequence of Lysinibacillus sphaericus, a Lignin-Degrading Bacterium Isolated from Municipal Solid Waste Soil. MICROBIOLOGY RESOURCE ANNOUNCEMENTS, v. 6, n. 18, MAY 2018. Web of Science Citations: 0. (15/50590-4)
RUBIO, MARCELO VENTURA; ZUBIETA, MARIANE PALUDETTI; LOURENO FRANCO CAIRO, JOAO PAULO; CALZADO, FELIPE; PAES LEME, ADRIANA FRANCO; SQUINA, FABIO MARCIO; PRADE, ROLF ALEXANDER; DE LIMA DAMASIO, ANDRE RICARDO. Mapping N-linked glycosylation of carbohydrate-active enzymes in the secretome of Aspergillus nidulans grown on lignocellulose. BIOTECHNOLOGY FOR BIOFUELS, v. 9, AUG 8 2016. Web of Science Citations: 8. (11/20977-3, 14/23051-2, 09/54067-3, 12/20549-4, 14/06923-6, 14/15403-6, 13/24988-5)
COLUSSI, FRANCIELI; DA SILVA, VIVIAM M.; MILLER, IAN; COTA, JUNIO; DE OLIVEIRA, LEANDRO C.; DE OLIVEIRA NETO, MARIO; SQUINA, FABIO M.; GARCIA, WANIUS. Oligomeric state and structural stability of two hyperthermophilic beta-glucosidases from Thermotoga petrophila. Amino Acids, v. 47, n. 5, p. 937-948, MAY 2015. Web of Science Citations: 8. (11/13242-7, 12/03503-0, 08/58037-9, 12/21054-9)
DE OLIVEIRA, LEANDRO C.; DA SILVA, VIVIAM M.; COLUSSI, FRANCIELI; CABRAL, ALINE D.; DE OLIVEIRA NETO, MARIO; SQUINA, FABIO M.; GARCIA, WANIUS. Conformational Changes in a Hyperthermostable Glycoside Hydrolase: Enzymatic Activity Is a Consequence of the Loop Dynamics and Protonation Balance. PLoS One, v. 10, n. 2, FEB 27 2015. Web of Science Citations: 16. (12/21054-9, 11/13242-7, 08/58037-9, 12/03503-0)
TRAMONTINA, ROBSON; GALMAN, JAMES L.; PARMEGGIANI, FABIO; DERRINGTON, SASHA R.; BUGG, TIMOTHY D. H.; TURNER, NICHOLAS J.; SQUINA, FABIO M.; DIXON, NEIL. Consolidated production of coniferol and other high-value aromatic alcohols directly from lignocellulosic biomass. GREEN CHEMISTRY, v. 22, n. 1, p. 144-152, JAN 7 2020. Web of Science Citations: 0. (15/50590-4, 17/23754-1)
CONTESINI, FABIANO JARES; LIBERATO, MARCELO VIZONA; RUBIO, MARCELO VENTURA; CALZADO, FELIPE; ZUBIETA, MARIANE PALUDETTI; RIANO-PACHON, DIEGO MAURICIO; SQUINA, FABIO MARCIO; BRACHT, FABRICIO; SKAF, MUNIR S.; DAMASIO, ANDRE RICARDO. Structural and functional characterization of a highly secreted alpha-L-arabinofuranosidase (GH62) from Aspergillus nidulans grown on sugarcane bagasse. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, v. 1865, n. 12, p. 1758-1769, DEC 2017. Web of Science Citations: 6. (14/23051-2, 12/20549-4, 13/08293-7, 14/04105-4, 13/24988-5, 14/15403-6, 08/58037-9)
LIMA, CLEILTON S.; RABELO, SARITA C.; CIESIELSKI, PETER N.; ROBERTO, INES C.; ROCHA, GEORGE J. M.; DRIEMEIER, CARLOS. Multiscale Alterations in Sugar Cane Bagasse and Straw Submitted to Alkaline Deacetylation. ACS SUSTAINABLE CHEMISTRY & ENGINEERING, v. 6, n. 3, p. 3796-3804, MAR 2018. Web of Science Citations: 1. (15/50590-4)
HAHN SCHNEIDER, WILLIAN DANIEL; GONCALVES, THIAGO AUGUSTO; UCHIMA, CRISTIANE AKEMI; DOS REIS, LAISA; FONTANA, ROSELEI CLAUDETE; SQUINA, FABIO MARCIO; PINHEIRO DILLON, ALDO JOSE; CAMASSOLA, MARLI. Comparison of the production of enzymes to cell wall hydrolysis using different carbon sources by Penicillium echinulaturn strains and its hydrolysis potential for lignocelullosic biomass. Process Biochemistry, v. 66, p. 162-170, MAR 2018. Web of Science Citations: 2. (08/58037-9)
FRANCO CAIRO, JOAO P. L.; CARAZZOLLE, MARCELO F.; LEONARDO, FLAVIA C.; MOFATTO, LUCIANA S.; BRENELLI, LIVIA B.; GONCALVES, THIAGO A.; UCHIMA, CRISTIANE A.; DOMINGUES, ROMANIA R.; ALVAREZ, THABATA M.; TRAMONTINA, ROBSON; et al. Expanding the Knowledge on Lignocellulolytic and Redox Enzymes of Worker and Soldier Castes from the Lower Termite Coptotermes gestroi. FRONTIERS IN MICROBIOLOGY, v. 7, OCT 13 2016. Web of Science Citations: 8. (11/20977-3, 13/03061-0, 14/10351-8, 12/19040-0, 10/11469-1, 14/50371-8, 15/06971-3, 14/20576-7, 08/58037-9)
BRENELLI, LIVIA BEATRIZ; MANDELLI, FERNANDA; MERCADANTE, ADRIANA ZERLOTTI; DE MORAES ROCHA, GEORGE JACKSON; ROCCO, SILVANA APARECIDA; CRAIEVICH, ALDO FELIX; GONCALVES, ADILSON ROBERTO; CENTENO, DANILO DA CRUZ; DE OLIVEIRA NETO, MARIO; SQUINA, FABIO MARCIO. Acidification treatment of lignin from sugarcane bagasse results in fractions of reduced polydispersity and high free-radical scavenging capacity. INDUSTRIAL CROPS AND PRODUCTS, v. 83, p. 94-103, MAY 2016. Web of Science Citations: 10. (14/50371-8, 13/03061-0)
SODRE, VICTORIA; ARAUJO, JUSCEMACIA NASCIMENTO; GONCALVES, THIAGO AUGUSTO; VILELA, NATHALIA; KIMUS BRAZ, ANTONIO SERGIO; FRANCO, TELMA TEIXEIRA; NETO, MARIO DE OLIVEIRA; DE LIMA DAMASIO, ANDRE RICARDO; GARCIA, WANIUS; SQUINA, FABIO MARCIO. An alkaline active feruloyl-CoA synthetase from soil metagenome as a potential key enzyme for lignin valorization strategies. PLoS One, v. 14, n. 2, FEB 25 2019. Web of Science Citations: 1. (15/50612-8, 17/16976-8, 17/17275-3, 18/18101-1, 17/05901-7, 17/22669-0, 17/08166-6, 15/50590-4, 17/16089-1)
RUBIO, MARCELO VENTURA; ZUBIETA, MARIANE PALUDETTI; LOURENO FRANCO CAIRO, JOAO PAULO; CALZADO, FELIPE; PAES LEME, ADRIANA FRANCO; SQUINA, FABIO MARCIO; PRADE, ROLF ALEXANDER; DE LIMA DAMASIO, ANDRE RICARDO. Mapping N-linked glycosylation of carbohydrate-active enzymes in the secretome of Aspergillus nidulans grown on lignocellulose. BIOTECHNOLOGY FOR BIOFUELS, v. 9, AUG 8 2016. Web of Science Citations: 8. (11/20977-3, 14/23051-2, 09/54067-3, 12/20549-4, 14/06923-6, 14/15403-6, 13/24988-5)
COLUSSI, FRANCIELI; DA SILVA, VIVIAM M.; MILLER, IAN; COTA, JUNIO; DE OLIVEIRA, LEANDRO C.; DE OLIVEIRA NETO, MARIO; SQUINA, FABIO M.; GARCIA, WANIUS. Oligomeric state and structural stability of two hyperthermophilic beta-glucosidases from Thermotoga petrophila. Amino Acids, v. 47, n. 5, p. 937-948, MAY 2015. Web of Science Citations: 8. (11/13242-7, 12/03503-0, 08/58037-9, 12/21054-9)
DE OLIVEIRA, LEANDRO C.; DA SILVA, VIVIAM M.; COLUSSI, FRANCIELI; CABRAL, ALINE D.; DE OLIVEIRA NETO, MARIO; SQUINA, FABIO M.; GARCIA, WANIUS. Conformational Changes in a Hyperthermostable Glycoside Hydrolase: Enzymatic Activity Is a Consequence of the Loop Dynamics and Protonation Balance. PLoS One, v. 10, n. 2, FEB 27 2015. Web of Science Citations: 16. (12/21054-9, 11/13242-7, 08/58037-9, 12/03503-0)
PIMENTEL, AGNES C.; EMATSU, GABRIELA C. G.; LIBERATO, MARCELO V.; PAIXAO, DOUGLAS A. A.; FRANCO CAIRO, JOAO PAULO L.; MANDELLI, FERNANDA; TRAMONTINA, ROBSON; GANDIN, CESAR A.; DE OLIVEIRA NETO, MARIO; SQUINA, FABIO M.; et al. Biochemical and biophysical properties of a metagenome-derived GH5 endoglucanase displaying an unconventional domain architecture. International Journal of Biological Macromolecules, v. 99, p. 384-393, JUN 2017. Web of Science Citations: 5. (14/12861-3, 10/11469-1, 14/04105-4, 14/06923-6, 16/01926-2, 08/58037-9)
BRENELLI, LIVIA; SQUINA, FABIO M.; FELBY, CLAUS; CANNELLA, DAVID. Laccase-derived lignin compounds boost cellulose oxidative enzymes AA9. BIOTECHNOLOGY FOR BIOFUELS, v. 11, JAN 17 2018. Web of Science Citations: 25. (15/07008-2)
HOFFMAM, ZAIRA B.; OLIVEIRA, LEANDRO C.; COTA, JUNIO; ALVAREZ, THABATA M.; DIOGO, JOS A.; NETO, MARIO DE OLIVEIRA; CITADINI, ANA PAULA S.; LEITE, VITOR B. P.; SQUINA, FABIO M.; MURAKAMI, MARIO T.; et al. Characterization of a Hexameric Exo-Acting GH51 alpha-l-Arabinofuranosidase from the Mesophilic Bacillus subtilis. MOLECULAR BIOTECHNOLOGY, v. 55, n. 3, p. 260-267, NOV 2013. Web of Science Citations: 6. (11/13242-7, 10/51890-8, 11/14200-6, 11/17658-3, 08/58037-9)
HAHN SCHNEIDER, WILLIAN DANIEL; GONCALVES, THIAGO AUGUSTO; UCHIMA, CRISTIANE AKEMI; COUGER, MATTHEW BRIAN; PRADE, ROLF; SQUINA, FABIO MARCIO; PINHEIRO DILLON, ALDO JOSE; CAMASSOLA, MARLI. Penicillium echinulatum secretome analysis reveals the fungi potential for degradation of lignocellulosic biomass. BIOTECHNOLOGY FOR BIOFUELS, v. 9, MAR 17 2016. Web of Science Citations: 23. (14/06923-6, 08/58037-9, 12/19040-0)
GOLDBECK, ROSANA; GONCALVES, THIAGO A.; DAMASIO, ANDRE R. L.; BRENELLI, LIVIA B.; WOLF, LUCIA D.; PAIXAO, DOUGLAS A. A.; ROCHA, GEORGE J. M.; SQUINA, FABIO M.. Effect of hemicellulolytic enzymes to improve sugarcane bagasse saccharification and xylooligosaccharides production. JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, v. 131, p. 36-46, SEP 2016. Web of Science Citations: 6. (12/20549-4, 12/18859-5)
MORAES, EDUARDO C.; ALVAREZ, THABATA M.; PERSINOTI, GABRIELA F.; TOMAZETTO, GEIZECLER; BRENELLI, LIVIA B.; PAIXAO, DOUGLAS A. A.; EMATSU, GABRIELA C.; ARICETTI, JULIANA A.; CALDANA, CAMILA; DIXON, NEIL; et al. Lignolytic-consortium omics analyses reveal novel genomes and pathways involved in lignin modification and valorization. BIOTECHNOLOGY FOR BIOFUELS, v. 11, MAR 22 2018. Web of Science Citations: 10. (15/23279-6, 13/03061-0, 15/50590-4, 14/26152-4)
BORIN, GUSTAVO PAGOTTO; SANCHEZ, CAMILA CRISTINA; DE SANTANA, ELIANE SILVA; ZANINI, GUILHERME KEPPE; CORREA DOS SANTOS, RENATO AUGUSTO; PONTES, ANGELICA DE OLIVEIRA; DE SOUZA, ALINE TIEPPO; TAVARES SOARES DAL'MAS, ROBERTA MARIA MENEGALDO; RIANO-PACHON, DIEGO MAURICIO; GOLDMAN, GUSTAVO HENRIQUE; et al. Comparative transcriptome analysis reveals different strategies for degradation of steam-exploded sugarcane bagasse by Aspergillus niger and Trichoderma reesei. BMC Genomics, v. 18, JUN 30 2017. Web of Science Citations: 22. (15/08222-8, 14/11733-1, 13/09541-4, 14/11766-7, 11/08945-9, 14/15799-7)
ALVAREZ, THABATA MARIA; LIBERATO, MARCELO VIZONA; FRANCO CAIRO, JOO PAULO L.; PAIXO, DOUGLAS A. A.; CAMPOS, BRUNA M.; FERREIRA, MARCEL R.; ALMEIDA, RODRIGO F.; PEREIRA, ISABELA O.; BERNARDES, AMANDA; EMATSU, GABRIELA C. G.; et al. A Novel Member of GH16 Family Derived from Sugarcane Soil Metagenome. Applied Biochemistry and Biotechnology, v. 177, n. 2, p. 304-317, SEP 2015. Web of Science Citations: 2. (10/11469-1, 08/58037-9)
MANDELLI, FERNANDA; RAMIRES, BRENDA OLIVEIRA; COUGER, MATTHEW BRIAN; PAIXAO, DOUGLAS A. A.; CAMILO, CESAR M.; POLIKARPOV, IGOR; PRADE, ROLF; RIANO-PACHON, DIEGO M.; SQUINA, FABIO M.. Draft Genome Sequence of the Thermophile Thermus filiformis ATCC 43280, Producer of Carotenoid-(Di)glucoside-Branched Fatty Acid (Di)esters and Source of Hyperthermostable Enzymes of Biotechnological Interest. MICROBIOLOGY RESOURCE ANNOUNCEMENTS, v. 3, n. 3, MAY-JUN 2015. Web of Science Citations: 0. (14/50371-8)
(References retrieved automatically from State of São Paulo Research Institutions)
ALVAREZ, Thabata Maria. Desenvolvimento de uma biblioteca de enzimas a partir de metagenoma de solo = : Library generation for biomass conversion enzymes from soil metagenome. Tese (Doutorado) - Instituto de Biologia. Universidade Estadual de Campinas (UNICAMP). (10/11469-1)
None
HOFFMAM, Zaira Bruna. Estudos funcionais e estruturais de hemicelulases para potencial aplicação biotecnológica. Dissertação (Mestrado) - Instituto de Biologia. Universidade Estadual de Campinas (UNICAMP). (11/14200-6)
PAIVA, Lívia Beatriz Brenelli de. Application of chemical and biological approaches for lignin valorization = Aplicação de abordagens químicas e biológicas para valorização da lignina. Tese (Doutorado) - Universidade Estadual de Campinas, Instituto de Biologia. (13/03061-0)
SANCHEZ, Camila Cristina. Estudos genômicos da expressão gênica global de "Aspergillus niger" crescido em bagaço e colmo de cana-de-açúcar = Global gene expression of "Aspergillus niger" grown on bagasse and culm of sugarcane. Dissertação (Mestrado) - Centro Nacional de Pesquisa em Energia e Materiais (CNPEM). Ministério da Ciência, Tecnologia, Inovações e Comunicações (Brasil). (13/09541-4)
CAIRO, João Paulo Lourenço Franco. Investigação de vias de degradação de biomassa lignocelulósica no cupim Coptotermes gestroi complementares a hidrolases glicosídicas visando aplicação na produção de bioprodutos : Investigation of lignocellulosic degradation by the termite Coptotermes gestroi complementary to glycoside hydrolases aiming at the production of bioproducts. Tese (Doutorado) - Universidade Estadual de Campinas, Instituto de Biologia. (11/20977-3)
PIMENTEL, Agnes Cristina. Características bioquímicas e estruturais do domínio catalítico da celulase CelE2 e sua relação com o domínio acessório Calx-beta : Biochemical and structural features of the catalytic domain of cellulase CelE2 and its relation with the Calx-beta accessory domain. Dissertação (Mestrado) - Centro Nacional de Pesquisa em Energia e Materiais (CNPEM). Ministério da Ciência, Tecnologia, Inovações e Comunicações (Brasil). (16/01926-2)
COMPOSIÇÃO DE ENZIMAS LIGNOCELULOLÍTICAS, MÉTODO DE CONVERSÃO ENZIMÁTICA E VETOR DE EXPRESSÃO DE UMA SUPERÓXIDO DISMUTASE BR1020150172567 - Centro Nacional de Pesquisa em Energia e Materiais (CNPEM); Universidade Estadual de Campinas (UNICAMP); Universidade Estadual Paulista (UNESP). Falsarella Carazzole; Fernanda Mandelli; Jose Geraldo Da Cruz Pradella; Thabata Maria Alvarez; Flávia Costa Leonardo; Fernando Ferreira Costa; Ana Maria Costa Leonardo; Robson Tramontina; Livia Beatriz Brenelli De Paiva; Thiago Augusto Gonçalves; Diogo Robl - July 2015, 20
COMPOSITION OF LIGNOCELLULOLYTIC ENZYMES, ENZYMATIC CONVERSION METHOD AND SUPEROXIDE DISMUTASE EXPRESSION VECTOR PCT/BR2016/000069 - Centro Nacional de Pesquisa em Energia e Materiais (CNPEM); Universidade Estadual de Campinas (UNICAMP); Universidade Estadual Paulista (UNESP). Gonçalo Amarante Guimarães Pereira; João Paulo Lourenço Cairo; Fábio Marcio Squina; Marcelo Falsarella Carazzole; Fernanda Mandelli; José Geraldo da Cruz Pradella; Thabata Maria Alvarez; Flávia Costa Leonardo; Fernando Ferreira Costa; Ana Maria Costa Leonardo; Robson Tramontina; Livia Beatriz Brenelli de Paiva; Thiago Augusto Gonçalves; Diogo Robl - July 2016, 18