Cláudio Romero Farias Marinho in research grants and scholarships supported by FAPESP.
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Malaria in pregnancy is characterized by the presence of Plasmodium spp. in the peripheral blood or placenta, being one of the main causes of mortality in tropical regions, which causes maternal anemia, abortion, intrauterine growth restriction, preterm delivery and low birth weight. Plasmodium (P.) vivax is the dominant malaria species outside the African continent, accounting for about …
It is estimated that approximately 125 million women in endemic Plasmodium countries get pregnant every year and, therefore, face an increased risk of acquiring malaria followed by its complications. Frequently is observed a recrudescence of the infection during pregnancy, suggesting a complex pathogenic mechanism linked to an imbalance of the immune response responsible for infection con…
Over 100 million pregnant women are at risk of malaria each year. Effects include maternal anemia, miscarriage and low birth weight, and central to their pathogenesis is the placental sequestration of Plasmodium falciparum- infected erythrocytes (IE), termed placental malaria, and mediated by a parasite protein called VAR2CSA. First-time mothers are at greatest risk, as they lack antibody…
Malaria in pregnancy is a major public health problem in countries where the disease is endemic, causing maternal and infant morbidity and mortality. It remains unclear why pregnant women are more susceptible to malaria. However, it is known that the placenta provides a favorable environment to the development of certain parasite subpopulations, triggering an intense inflammatory infiltra…
(Only some records are available in English at this moment)
An increase in cardiovascular diseases recorded in developing countries appears to occur simultaneously with an increase in the burden of infectious diseases. In this sense, Malaria is a highly prevalent infectious disease in these places, where approximately 230 million cases are recorded per year. There are some studies and case reports that suggest that Malaria causes structural change…
Malaria in pregnancy is characterized by the presence of Plasmodium spp. in maternal circulation, being one of the main causes of mortality in tropical regions, causing maternal anemia, abortion, premature birth, low birth weight, and Intrauterine Growth Restriction (IUGR). Therefore, IUGR is one of the main consequences of gestational Malaria, occurring in about 13% to 70% of cases. Alth…
Malaria is the main parasitic human disease, responsible for more than 200 million cases and about 400 thousand deaths per year. Every year at least 50 million pregnant women are exposed to Malaria, which represents an increased risk for the life of the mother and the developing fetus. Pregnancy-associated Malaria is characterized by sequestration of parasites in the placenta, and consequ…
Malaria in pregnancy is characterized as the presence of Plasmodium spp. in the peripheral blood or placenta, being one of the main causes of mortality in tropical regions, causing maternal Anemia, abortion, intrauterine growth restriction, preterm delivery and low birth weight. Placental Malaria is one of the serious consequences of Malaria in pregnancy, occurring in about 20% to 50% of …
Malaria is a severe public health problem around the world, especially in developing countries where it is responsible for approximately 500 000 deaths every year. Pregnant women are more prone to develop severe infection than non-pregnant counterparts due to the existence are of the placenta. Erythrocytes infected with Plasmodium spp. accumulate inside this organ leading to the developme…
Malaria in pregnancy is a major public health problem in countries where the disease is endemic, causing maternal and infant morbidity and mortality. It remains unclear why pregnant women are more susceptible to malaria. However, it is known that the placenta provides a favorable environment to the development of certain parasite subpopulations, triggering an intense inflammatory infiltra…
(Only some records are available in English at this moment)
Malaria in pregnancy is a serious public health problem, with placental malaria being one of its serious consequences and one of the main causes of adverse pregnancy outcomes. Despite many studies, it remains unclear which peripheral blood infections during pregnancy lead to development of placental malaria. Whereas it is clear that placental parasites present a distinct phenotype from th…
Malaria in pregnancy is a serious public health problem and is characterized by the presence of Plasmodium spp. in the peripheral blood or the placenta, impacting on maternal and foetal health. Although P. vivax burden in pregnancy is less described than P. falciparum, recent studies indicate that both species represent a threaten to mother and foetus. Nevertheless, several hypotheses hav…
| 1 / 1 | Ongoing research grants |
| 6 / 6 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 11 / 11 | Completed scholarships in Brazil |
| 1 / 1 | Ongoing scholarships abroad |
| 1 / 1 | Completed scholarships abroad |
| 23 / 23 | All research grants and scholarships |
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