Cláudio Romero Farias Marinho in research grants and scholarships supported by FAPESP.
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Malaria remains a significant global health issue, with millions of cases and hundreds of thousands of deaths annually, predominantly caused by Plasmodium falciparum (Pf) and Plasmodium vivax (Pv). Control efforts are complicated by emerging drug resistance, particularly against artemisinin-based treatments (ACTs). While artemisinin resistance is primarily observed in Southeast Asia, the …
The increase in cardiovascular disease in developing countries seems to occur in the setting of high incedence infectious diseases. Malaria is a highly prevalent infectious disease in these regions, with 230 million cases per year. There are some studies suggesting that malaria causes structural changes in the heart and affects specific vascular pathways, leading to an increased risk of h…
Malaria in pregnancy is characterized by the presence of Plasmodium spp. in the peripheral blood or placenta, being one of the main causes of mortality in tropical regions, which causes maternal anemia, abortion, intrauterine growth restriction, preterm delivery and low birth weight. Plasmodium (P.) vivax is the dominant malaria species outside the African continent, accounting for about …
It is estimated that approximately 125 million women in endemic Plasmodium countries get pregnant every year and, therefore, face an increased risk of acquiring malaria followed by its complications. Frequently is observed a recrudescence of the infection during pregnancy, suggesting a complex pathogenic mechanism linked to an imbalance of the immune response responsible for infection con…
Over 100 million pregnant women are at risk of malaria each year. Effects include maternal anemia, miscarriage and low birth weight, and central to their pathogenesis is the placental sequestration of Plasmodium falciparum- infected erythrocytes (IE), termed placental malaria, and mediated by a parasite protein called VAR2CSA. First-time mothers are at greatest risk, as they lack antibody…
(Only some records are available in English at this moment)
Malaria remains the most important parasitic disease worldwide due to its high morbidity and mortality and its wide geographical distribution in tropical regions. In Brazil, this disease is mainly caused by Plasmodium vivax species and more than 99% of cases occur in the Legal Amazon region. Genetic components of the parasite and the host can influence the infection course, such as the pr…
Malaria represents a public health problem in most tropical countries, with high incidence and mortality rates,and with pregnant women being a risk group for the disease. During pregnancy, infection with Plasmodium falciparum induce the increase of prematurity and maternal and fetal mortality, in addition to intrauterine growth restriction, which leads to low birth weight.In this context,…
An increase in cardiovascular diseases recorded in developing countries appears to occur simultaneously with an increase in the burden of infectious diseases. In this sense, Malaria is a highly prevalent infectious disease in these places, where approximately 230 million cases are recorded per year. There are some studies and case reports that suggest that Malaria causes structural change…
Malaria in pregnancy is characterized by the presence of Plasmodium spp. in maternal circulation, being one of the main causes of mortality in tropical regions, causing maternal anemia, abortion, premature birth, low birth weight, and Intrauterine Growth Restriction (IUGR). Therefore, IUGR is one of the main consequences of gestational Malaria, occurring in about 13% to 70% of cases. Alth…
(Only some records are available in English at this moment)
Malaria still represents a burden worldwide and pregnant women are at risk of developing placental malaria, a complication of Plasmodium falciparum infections with sequestration of infected red blood cells in the placenta intervillous space. This complication is associated with placental insufficiency, which leads to adverse outcomes, such as stillbirth, low birth weight, prematurity, and…
Malaria in pregnancy is a serious public health problem, with placental malaria being one of its serious consequences and one of the main causes of adverse pregnancy outcomes. Despite many studies, it remains unclear which peripheral blood infections during pregnancy lead to development of placental malaria. Whereas it is clear that placental parasites present a distinct phenotype from th…
Malaria in pregnancy is a serious public health problem and is characterized by the presence of Plasmodium spp. in the peripheral blood or the placenta, impacting on maternal and foetal health. Although P. vivax burden in pregnancy is less described than P. falciparum, recent studies indicate that both species represent a threaten to mother and foetus. Nevertheless, several hypotheses hav…
| 2 / 2 | Ongoing research grants |
| 8 / 7 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 15 / 15 | Completed scholarships in Brazil |
| 1 / 1 | Ongoing scholarships abroad |
| 2 / 2 | Completed scholarships abroad |
| 29 / 28 | All research grants and scholarships |
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