CV Lattes
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ORCID
Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation for the last research proposal) Birthplace: Brazil
Graduated in Physical Education by the Universidade of Ribeirão Preto (1998) Obtained Ph.D. at Physiology Department from University of São Paulo (2004) under the mentorship of Dr Renato Migliorini (1999-2004). Worked as a Research Scholar at the lab of Dr Timothy Bartness in Atlanta GA, USA (2002-2003). Received Post-doctoral training at the Quebec Institute of Cardiology and Pneumology, Quebec, Canada, under supervision of Dr Yves Deshaies (2005-2009). Worked as a Visiting Scientist at the laboratory of Dr David Sabatini at the Whitehead Institute For Biomedical Research associated to the MIT (Massachusetts Institute of Technology), Cambridge, USA (2009-2010). Currrently, work as Associated Professor at the Institute of Biomedical Sciences, University of São Paulo. Has experience in Human Physiology, focusing on neural, hormonal and molecular control of lipids, carbohydrates and protein metabolism and intracellular signaling via mTOR. (Source: Lattes Curriculum)
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Evidence gathered in the last decades suggests that lipotoxicity and inflammation, through still not completed defined molecular mechanisms, are the main factors connecting adipose tissue dysfunction to the development nonalcoholic fatty liver disease (NAFLD), a group of liver diseases that comprises from a simple hepatic steatosis (NAFL) to more severe steatohepatitis (NASH), cirrhosis a…
Evidence gathered in the last decades suggests that lipotoxicity and inflammation, through still not completed defined molecular mechanisms, are the main factors connecting adipose tissue dysfunction to the development nonalcoholic fatty liver disease (NAFLD), a group of liver diseases that comprises from a simple hepatic steatosis (NAFL) to more severe steatohepatitis (NASH), cirrhosis a…
Lipodystrophy comprises a group of diseases characterized by either a partial or a complete reduction in adipose mass that is associated with the development of several metabolic diseases such as insulin resistance, dyslipidemia, hypertension, hepatic steatosis and atherosclerosis, among others. In this proposal, we will investigate in 3 integrated research programs the molecular mechanis…
(Only some records are available in English at this moment)
The exponential growth of obesity worldwide is increasing the prevalence of several chronic diseases commonly associated to excessive adiposity such as type 2 diabetes, hepatic steatosis and some types of cancer. Despite of its major impact worldwide, little is known about the mechanisms that link obesity to the development of its associated chronic diseases. Being obesity a condition cha…
Role of adipose tissue in the development of obesity and associated co-morbidities: investigation of molecular mechanism and search for alternative therapies. The exponential growth of obesity in the world is associated with a marked increase in the prevalence of several morbidities directly associated with excessive adiposity as Type 2 Diabetes (T2D), Metabolic Syndrome (MS), atheroscler…
The exponential growth of obesity in the world is associated with a marked increase in the prevalence of several morbidities directly associated with excessive adiposity as Type 2 Diabetes (T2D), Metabolic Syndrome (MS), atherosclerosis, hypertension, stroke, hepatic steatosis and some types of cancer. The main goal of the current research proposal is to investigate the molecular mechanis…
Non-alcoholic liver disease associated with metabolic dysfunction (MAFLD) is a heterogenous group of diseases that comprise from a simple liver steatosis (NAFL) to more severe conditions such as Steatohepatitis (NASH), Cirrhosis and Hepatocellular Carcinoma (HCC). The PI3K-mTORC2-Akt-mTORC1 signaling pathway is directly involved in the NAFL-NASH-HCC progression and overactivated in 40-50%…
Preliminary results obtained at undergraduated scientific training suggest that constitutive mTORC1 activation induced by Tsc1 deletion in adipocytes increases adipose tissue BCAA oxidation and lipolysis. Considering these findings, in this master proposal, we will test the hypothesis that mTORC1 is a major regulator of adipose tissue BCAAmetabolismo and lipolysis in visceral, subcutaneou…
(Only some records are available in English at this moment)
The exponential growth of obesity worldwide is increasing the prevalence of several chronic diseases commonly associated to excessive adiposity such as type 2 diabetes, hepatic steatosis and some types of cancer. Despite of its major impact worldwide, little is known about the mechanisms that link obesity to the development of its associated chronic diseases. Being obesity a condition cha…
Several lines of evidence suggest that obesity and lipodystrophy share common properties related to the buffering capacity of adipose tissue (AT) to adequately store fat, leading to redistribution and deposition of lipids in skeletal muscle, liver and pancreas (Snel et al., 2012). Since those organs and tissues do not possess the proper enzymatic machinery for fat storage, the local accum…
(Only some records are available in English at this moment)
The central regulators of autophagy are the serine/threonine kinases unc-51 like autophagy activating kinase 1/2 (ULK1 and ULK2) that participate in the onset of the autophagic cellular process. These kinases in addition to initiate the autophagic cascade, seem to have interesting secondary roles in energy metabolism to coordinate the cellular response to starvation, such as increasing gl…
The thiazolidinediones (TZDs) are anti-diabetic drugs whose use in treating type 2 diabetes is limited by adverse side effects. The goal of this proposal is a biochemical investigation into a mechanism that separates the positive metabolic effects of TZDs from their side effects. PPAR³, the molecular target of the TZDs, is a key regulator of systemic insulin sensitivity, adipogenesis, inf…
In this project, we will continue to collect human adipocyte samples and generate RNA-seq and histone modification ChIP-seq libraries to assess genome-wide transcriptional and epigenomic states. We have identified key cis-regulatory elements with altered activity in the IR state and have determined the candidate transcription factors (TFs) that bind them. We will validate the importance …
(Only some records are available in English at this moment)
| 4 / 4 | Ongoing research grants |
| 5 / 3 | Completed research grants |
| 6 / 6 | Ongoing scholarships in Brazil |
| 20 / 17 | Completed scholarships in Brazil |
| 6 / 6 | Completed scholarships abroad |
| 41 / 36 | All research grants and scholarships |
| Associated processes | |
BOLSONI-LOPES, ANDRESSA; FESTUCCIA, WILLIAM T.; FARIAS, TALITA S. M.; CHIMIN, PATRICIA; TORRES-LEAL, FRANCISCO L.; DEROGIS, PRISCILLA B. M.; DE ANDRADE, PAULA B.; MIYAMOTO, SAYURI; LIMA, FABIO B.; CURI, RUI; et al. Palmitoleic acid (n-7) increases white adipocyte lipolysis and lipase content in a PPAR alpha-dependent manner. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, v. 305, n. 9, p. E1093-E1102, NOV 2013. (10/10909-8, 11/51627-8, 09/15354-7)
FESTUCCIA, WILLIAM T.; BLANCHARD, PIERRE-GILLES; OLIVEIRA, THIAGO B.; MAGDALON, JULIANA; PASCHOAL, VIVIAN A.; RICHARD, DENIS; DESHAIES, YVES. PPAR gamma activation attenuates cold-induced upregulation of thyroid status and brown adipose tissue PGC-1 alpha and D2. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, v. 303, n. 12, p. R1277-R1285, DEC 2012. (10/10909-8, 09/15354-7)
MAGDALON, JULIANA; CHIMIN, PATRICIA; BELCHIOR, THIAGO; NEVES, RODRIGO X.; VIEIRA-LARA, MARCEL A.; ANDRADE, MAYNARA L.; FARIAS, TALITA S.; BOLSONI-LOPES, ANDRESSA; PASCHOAL, VIVIAN A.; YAMASHITA, ALEX S.; et al. Constitutive adipocyte mTORC1 activation enhances mitochondrial activity and reduces visceral adiposity in mice. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, v. 1861, n. 5, p. 430-438, MAY 2016. (11/03972-8, 13/14203-0, 10/51906-1, 12/25317-4, 09/15354-7, 15/19530-5)
YAMASHITA, ALEX SHIMURA; ROSA, MARINA DA COSTA; BORODOVSKY, ALEXANDRA; FESTUCCIA, WILLIAM T.; CHAN, TIMOTHY; RIGGINS, GREGORY J.. Demethylation and epigenetic modification with 5-azacytidine reduces IDH1 mutant glioma growth in combination with temozolomide. NEURO-ONCOLOGY, v. 21, n. 2, p. 189-200, FEB 2019. (15/05828-2)
HALL, JESSICA A.; RAMACHANDRAN, DEEPTI; ROH, HYUN C.; DISPIRITO, JOANNA R.; BELCHIOR, THIAGO; ZUSHIN, PETER-JAMES H.; PALMER, COLIN; HONG, SHANGYU; MINA, I, AMIR; LIU, BINGYANG; et al. Obesity-Linked PPAR gamma S273 Phosphorylation Promotes Insulin Resistance through Growth Differentiation Factor 3. Cell Metabolism, v. 32, n. 4, p. 665+, OCT 6 2020. (17/25881-0)
GUERRA, BEATRIZ A.; BRANDAO, BRUNA B.; PINTO, SILAS S.; SALGUEIRO, WILLIAN G.; DE-SOUZA, EVANDRO A.; REIS, FELIPE C. G.; BATISTA, THIAGO M.; CAVALCANTE-SILVA, VANESSA; D'ALMEIDA, VANIA; CASTILHO, BEATRIZ A.; et al. Dietary sulfur amino acid restriction upregulates DICER to confer beneficial effects. MOLECULAR METABOLISM, v. 29, p. 124-135, NOV 2019. (15/03292-8, 17/22057-5, 10/52557-0, 16/02207-0, 17/01184-9, 15/01316-7, 15/19530-5, 12/07259-7, 17/07975-8)
FESTUCCIA, WILLIAM T.. Regulation of Adipocyte and Macrophage Functions by mTORC1 and 2 in Metabolic Diseases. MOLECULAR NUTRITION & FOOD RESEARCH, v. 65, n. 1, SI, MAR 2020. (15/19530-5)
SOUZA, CAMILA O.; TEIXEIRA, ALEXANDRE A. S.; BIONDO, LUANA AMORIM; SILVEIRA, LOREANA SANCHES; DE SOUZA BREDA, CRISTIANE N.; BRAGA, TARCIO T.; CAMARA, NIELS O. S.; BELCHIOR, THIAGO; FESTUCCIA, WILLIAM T.; DINIZ, TIEGO A.; et al. Palmitoleic acid reduces high fat diet-induced liver inflammation by promoting PPAR-gamma-independent M2a polarization of myeloid cells. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, v. 1865, n. 10, OCT 2020. (13/04765-1, 19/06172-4, 19/24112-9, 15/19530-5, 16/01409-8)
BELCHIOR, THIAGO; PASCHOAL, VIVIAN A.; MAGDALON, JULIANA; CHIMIN, PATRICIA; FARIAS, TALITA M.; CHAVES-FILHO, ADRIANO B.; GORJAO, RENATA; ST-PIERRE, PHILIPPE; MIYAMOTO, SAYURI; KANG, JING X.; et al. Omega-3 fatty acids protect from diet-induced obesity, glucose intolerance, and adipose tissue inflammation through PPAR gamma-dependent and PPAR gamma-independent actions. MOLECULAR NUTRITION & FOOD RESEARCH, v. 59, n. 5, p. 957-967, MAY 2015. (11/14172-2, 09/15354-7)
BLANCHARD, P. G.; TURCOTTE, V.; COTE, M.; GELINAS, Y.; NILSSON, S.; OLIVECRONA, G.; DESHAIES, Y.; FESTUCCIA, W. T.. Peroxisome proliferator-activated receptor activation favours selective subcutaneous lipid deposition by coordinately regulating lipoprotein lipase modulators, fatty acid transporters and lipogenic enzymes. ACTA PHYSIOLOGICA, v. 217, n. 3, p. 227-239, JUL 2016. (09/15354-7)
FESTUCCIA, WILLIAM T.; BLANCHARD, PIERRE-GILLES; BELCHIOR, THIAGO; CHIMIN, PATRICIA; PASCHOAL, VIVIAN A.; MAGDALON, JULIANA; HIRABARA, SANDRO M.; SIMOES, DANIEL; ST-PIERRE, PHILIPPE; CARPINELLI, ANGELO; et al. PPAR gamma activation attenuates glucose intolerance induced by mTOR inhibition with rapamycin in rats. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, v. 306, n. 9, p. E1046-E1054, MAY 2014. (09/15354-7)
BLANCHARD, PIERRE-GILLES; FESTUCCIA, WILLIAM T.; HOUDE, VANESSA P.; ST-PIERRE, PHILIPPE; BRULE, SOPHIE; TURCOTTE, VERONIQUE; COTE, MARIE; BELLMANN, KERSTIN; MARETTE, ANDRE; DESHAIES, YVES. Major involvement of mTOR in the PPAR gamma-induced stimulation of adipose tissue lipid uptake and fat accretion. Journal of Lipid Research, v. 53, n. 6, p. 1117-1125, JUN 2012. (10/10909-8, 09/15354-7)
PASCHOAL, VIVIAN A.; BELCHIOR, THIAGO; AMANO, MARIANE T.; BURGOS-SILVA, MARINA; PEIXOTO, ALBERT S.; MAGDALON, JULIANA; VIEIRA, THAYNA S.; ANDRADE, MAYNARA L.; MORENO, MAYARA F.; CHIMIN, PATRICIA; et al. Constitutive Activation of the Nutrient Sensor mTORC1 in Myeloid Cells Induced by Tsc1 Deletion Protects Mice from Diet-Induced Obesity. MOLECULAR NUTRITION & FOOD RESEARCH, v. 62, n. 17, SEP 2018. (11/10783-7, 12/02270-2, 09/15354-7, 15/19530-5)
CASTRO, ERIQUE; SILVA, TIAGO E. OLIVEIRA; FESTUCCIA, WILLIAM T.. Critical review of beige adipocyte thermogenic activation and contribution to whole-body energy expenditure. HORMONE MOLECULAR BIOLOGY AND CLINICAL INVESTIGATION, v. 31, n. 2, SI, AUG 2017. (16/07062-0, 16/23169-9, 15/19530-5)
PASCHOAL, VIVIAN A.; AMANO, MARIANE T.; BELCHIOR, THIAGO; MAGDALON, JULIANA; CHIMIN, PATRICIA; ANDRADE, MAYNARA L.; ORTIZ-SILVA, MILENE; CASTRO, ERIQUE; YAMASHITA, ALEX S.; ROSA NETO, JOSE CESAR; et al. mTORC1 inhibition with rapamycin exacerbates adipose tissue inflammation in obese mice and dissociates macrophage phenotype from function. Immunobiology, v. 222, n. 2, p. 261-271, FEB 2017. (11/10783-7, 12/02270-2, 09/15354-7, 15/19530-5)
CHAAR, LAIALI J.; COELHO, ALINE; SILVA, NATALIA M.; FESTUCCIA, WILLIAM L.; ANTUNES, VAGNER R.. High-fat diet-induced hypertension and autonomic imbalance are associated with an upregulation of CART in the dorsomedial hypothalamus of mice. PHYSIOLOGICAL REPORTS, v. 4, n. 11, JUN 2016. (13/06206-0, 11/13563-8, 09/15354-7, 10/19018-9, 15/19530-5)
CASTRO, ERIQUE; VIEIRA, THAYNA S.; OLIVEIRA, TIAGO E.; ORTIZ-SILVA, MILENE; ANDRADE, MAYNARA L.; TOMAZELLI, CAROLINE A.; PEIXOTO, ALBERT S.; SOBRINHO, CLEYTON R.; MORENO, MAYARA F.; GILIO, GUSTAVO R.; et al. Adipocyte-specific mTORC2 deficiency impairs BAT and iWAT thermogenic capacity without affecting glucose uptake and energy expenditure in cold-acclimated mice. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, v. 321, n. 5, p. E592-E605, NOV 2021. (16/23169-9, 19/25943-1, 17/23040-9, 15/13508-8, 17/17582-3, 18/03418-0, 17/17403-1, 17/12260-8, 19/01763-4, 19/17660-0, 15/19530-5, 20/09399-7, 19/04271-5, 12/25317-4)
YAMASHITA, ALEX S.; BELCHIOR, THIAGO; LIRA, FABIO S.; BISHOP, NICOLETTE C.; WESSNER, BARBARA; ROSA, JOSE C.; FESTUCCIA, WILLIAM T.. Regulation of Metabolic Disease-Associated Inflammation by Nutrient Sensors. Mediators of Inflammation, 2018. (15/22983-1, 15/19530-5, 13/15825-5)
DE CASTRO, GABRIELA S.; SIMOES, ESTEFANIA; LIMA, JOANNA D. C. C.; ORTIZ-SILVA, MILENE; FESTUCCIA, WILLIAM T.; TOKESHI, FLIVIO; ALCANTARA, PAULO S.; OTOCH, JOSE P.; COLETTI, DARIO; SEELAENDER, MARILIA. Human Cachexia Induces Changes in Mitochondria, Autophagy and Apoptosis in the Skeletal Muscle. CANCERS, v. 11, n. 9, SEP 2019. (16/02780-1, 12/50079-0, 16/13810-9, 16/12508-7, 17/12260-8)
BIRSOY, KIVANC; FESTUCCIA, WILLIAM T.; LAPLANTE, MATHIEU. A comparative perspective on lipid storage in animals. Journal of Cell Science, v. 126, n. 7, p. 1541-1552, APR 1 2013. (09/15354-7)
LAPLANTE‚ M.; HORVAT‚ S.; FESTUCCIA‚ W.T.; BIRSOY‚ K.; PREVORSEK‚ Z.; EFEYAN‚ A.; SABATINI‚ D.M.. DEPTOR Cell-Autonomously Promotes Adipogenesis, and Its Expression Is Associated with Obesity. Cell Metabolism, v. 16, n. 2, p. 202-212, 2012. (10/10909-8, 09/15354-7)
CHIMIN, PATRICIA; ANDRADE, MAYNARA L.; BELCHIOR, THIAGO; PASCHOAL, VIVIAN A.; MAGDALON, JULIANA; YAMASHITA, ALEX S.; CASTRO, ERIQUE; CASTOLDI, ANGELA; CHAVES-FILHO, ADRIANO B.; YOSHINAGA, MARCOS Y.; et al. Adipocyte mTORC1 deficiency promotes adipose tissue inflammation and NLRP3 inflammasome activation via oxidative stress and de novo ceramide synthesis. Journal of Lipid Research, v. 58, n. 9, p. 1797-1807, SEP 2017. (12/25317-4, 15/13508-8, 12/02270-2, 09/15354-7, 15/19530-5)
LABBE, SEBASTIEN M.; MOUCHIROUD, MATHILDE; CARON, ALEXANDRE; SECCO, BLANDINE; FREINKMAN, ELIZAVETA; LAMOUREUX, GUILLAUME; GELINAS, YVES; LECOMTE, ROGER; BOSSE, YOHAN; CHIMIN, PATRICIA; et al. mTORC1 is Required for Brown Adipose Tissue Recruitment and Metabolic Adaptation to Cold. SCIENTIFIC REPORTS, v. 6, NOV 23 2016. (15/19530-5)
BLANCHARD, PIERRE-GILLES; MOREIRA, RAFAEL J.; CASTRO, ERIQUE; CARON, ALEXANDRE; COTE, MARIE; ANDRADE, MAYNARA L.; OLIVEIRA, TIAGO E.; ORTIZ-SILVA, MILENE; PEIXOTO, ALBERT S.; DIAS, FRANCE ANNE; et al. PPAR gamma is a major regulator of branched-chain amino acid blood levels and catabolism in white and brown adipose tissues. METABOLISM-CLINICAL AND EXPERIMENTAL, v. 89, p. 27-38, DEC 2018. (16/07062-0, 16/23169-9, 15/13508-8, 17/12260-8, 15/19530-5)
OLIVEIRA, TIAGO E.; CASTRO, ERIQUE; BELCHIOR, THIAGO; ANDRADE, MAYNARA L.; CHAVES-FILHO, ADRIANO B.; PEIXOTO, ALBERT S.; MORENO, MAYARA F.; ORTIZ-SILVA, MILENE; MOREIRA, RAFAEL J.; INAGUE, ALEX; et al. Fish Oil Protects Wild Type and Uncoupling Protein 1-Deficient Mice from Obesity and Glucose Intolerance by Increasing Energy Expenditure. MOLECULAR NUTRITION & FOOD RESEARCH, v. 63, n. 7, APR 2019. (16/07062-0, 16/23169-9, 15/13508-8, 17/23040-9, 17/12260-8, 15/22983-1, 18/11156-5, 17/17582-3, 15/19530-5)
PAHLAVANI, MANDANA; RAMALINGAM, LATHA; MILLER, EMILY K.; SCOGGIN, SHANE; MENIKDIWELA, KALHARA R.; KALUPAHANA, NISHAN S.; FESTUCCIA, WILLIAM T.; MOUSTAID-MOUSSA, NAIMA. Eicosapentaenoic Acid Reduces Adiposity, Glucose Intolerance and Increases Oxygen Consumption Independently of Uncoupling Protein 1. MOLECULAR NUTRITION & FOOD RESEARCH, v. 63, n. 7, APR 2019. (15/19530-5)
FONSECA, MONIQUE T.; MORETTI, EDUARDO H.; MARQUES, LUCAS M. M.; MACHADO, BIANCA F.; BRITO, CAMILA F.; GUEDES, JADY T.; KOMEGAE, EVILIN N.; VIEIRA, THAYNA S.; FESTUCCIA, WILLIAM T.; LOPES, NORBERTO P.; et al. A leukotriene-dependent spleen-liver axis drives TNF production in systemic inflammation. Science Signaling, v. 14, n. 679, APR 20 2021. (16/23540-9, 18/03418-0, 17/17403-1, 17/13350-0, 15/19530-5, 16/04921-1, 20/09399-7, 14/50265-3, 14/03719-9, 18/00849-0)
MOREIRA, RAFAEL J.; CASTRO, ERIQUE; OLIVEIRA, TIAGO E.; BELCHIOR, THIAGO; PEIXOTO, ALBERT S.; CHAVES-FILHO, ADRIANO B.; MORENO, MAYARA F.; LIMA, JANAYNA D.; YOSHINAGA, MARCOS; MIYAMOTO, SAYURI; et al. Lipoatrophy-Associated Insulin Resistance and Hepatic Steatosis are Attenuated by Intake of Diet Rich in Omega 3 Fatty Acids. MOLECULAR NUTRITION & FOOD RESEARCH, v. 64, n. 7, FEB 2020. (17/17943-6, 18/15549-1, 13/07467-1, 16/04000-3, 14/06863-3, 13/07937-8, 15/19530-5)
ANDRADE, MAYNARA L.; GILIO, GUSTAVO R.; PERANDINI, LUIZ A.; PEIXOTO, ALBERT S.; MORENO, MAYARA F.; CASTRO, ERIQUE; OLIVEIRA, TIAGO E.; VIEIRA, THAYNA S.; ORTIZ-SILVA, MILENE; THOMAZELLI, CAROLINE A.; et al. PPAR gamma-induced upregulation of subcutaneous fat adiponectin secretion, glyceroneogenesis and BCAA oxidation requires mTORC1 activity. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, v. 1866, n. 8, AUG 2021. (19/17660-0, 16/23169-9, 18/11156-5, 17/17403-1, 17/17582-3, 17/23040-9, 15/22983-1, 13/07937-8, 19/04271-5, 15/13508-8, 19/01763-4, 15/19530-5, 17/12260-8)
DONADO-PESTANA, CARLOS M.; PESSOA, ERIKA V. M.; RODRIGUES, LARISSA; ROSSI, RAFAELA; MOURA, MARCIO H. C.; DOS SANTOS-DONADO, PRISCILA R.; CASTRO, ERIQUE; FESTUCCIA, WILLIAM T.; GENOVESE, MARIA INES. Polyphenols of cambuci (Campomanesia phaea (O. Berg.)) fruit ameliorate insulin resistance and hepatic steatosis in obese mice. Food Chemistry, v. 340, MAR 15 2021. (15/19530-5, 18/24477-4)
(References retrieved automatically from State of São Paulo Research Institutions)
PASCHOAL, Vivian Almeida. mTOR complexo 1 atenua a resposta pró-inflamatória de macrófagos e inflamação do tecido adiposo associadas à obesidade.. Tese (Doutorado) - Instituto de Ciências Biomédicas. Universidade de São Paulo (USP). São Paulo. (11/10783-7)
MAGDALON, Juliana. A ativação constitutiva de mTORC1 em adipócitos aumenta a capacidade oxidativa mitocondrial e reduz a adiposidade visceral em camundongos.. Tese (Doutorado) - Instituto de Ciências Biomédicas. Universidade de São Paulo (USP). São Paulo. (11/03972-8)
OLIVEIRA, Thiago Belchior de. Envolvimento dos PPARγ nas ações metabólicas dos ácidos graxos ômega-3.. Tese (Doutorado) - Instituto de Ciências Biomédicas. Universidade de São Paulo (USP). São Paulo. (11/14172-2)
SILVA, Tiago Eugênio Oliveira da. Ingestão de dieta hiperlipídica rica em óleo de peixe aumenta o gasto energético independentemente de UCP1.. Dissertação (Mestrado) - Instituto de Ciências Biomédicas. Universidade de São Paulo (USP). São Paulo. (16/07062-0)