CV Lattes
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Universidade Estadual de Campinas (UNICAMP). Instituto de Biologia (IB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduate at Enfermagem from Universidade Estadual de Campinas (1992), master's at Funcional and Molecular Biology from Universidade Estadual de Campinas (1989) and P.h.d. at Funcional and Molecular Biology from Universidade Estadual de Campinas (1996). Has experience in Physiology, focusing on Endocrinal Physiology, acting on the following subjects: secreção de insulina, ilhotas de langerhans, insulin, insulina and rats. (Source: Lattes Curriculum)
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Despite global efforts, undernutrition still affects thousands of people around the world. Undernutrition in the early stages of life, or during pregnancy/lactation, compromises the development and function of several organs, including the central nervous system (CNS), thus altering feeding behavior, in part, by increasing the expression of orexigenic genes (NPY and AgRP) in the hypothala…
Malnutrition still affects thousands of people around the world. In addition to the deaths, malnutrition during the early stages of life compromises the development of organs and tissues essential to the maintenance of glycemic, lipid and energetic metabolism. Reprogramming of such organs and tissues may lead to metabolic changes that increases susceptibility to the development of patholo…
Malnutrition still affects thousands of people around the world. In addition to the deaths, malnutrition during the early stages of life compromises the development of organs and tissues essential to the maintenance of glycemic, lipid and energetic metabolism. Reprogramming of such organs and tissues may lead to metabolic changes that increases susceptibility to the development of patholo…
(Only some records are available in English at this moment)
In this system, the microscope is coupled to a perfusion system that allows dynamic assessment of the fluorescence in different experimental situations. In our laboratory, the system is used to measure Ca 2+ ion influx (Fura-2), the bioavailability of NAD (P) H (autofluorescence) and ATP (Magnesium Green). In addition to the use described in our laboratory, this equipment can also assess,…
Intrauterine and early life nutritional deficiency favors metabolic and cardiovascular disorders such as hypertension and insulin resistance. In this context, insulinotropic amino acids may act as a complementary therapy. Currently our group investigates the effects of amino acids depletion in vitro on insulin secretion and action. So far, we have reported that the in vitro withdrawal of …
Epidemiological data shows obesity and type 2 diabetes burst in developing countries and its relationship with imbalanced diet consumption throughout life span. Insulin secretion impairment is pointed as one of the main alterations related with the incidence of these diseases. Our group has shown several diet-induced molecular and functional effects upon insulin secretion mechanism in pro…
(Only some records are available in English at this moment)
One of the objectives of this Thematic Project is to investigate the molecular mechanisms involved on the signaling of metabolic programming induced by amino acid restriction. For that we intend to run a high performance analysis, using the technique of RNA-sequencing (RNA-seq) to elect potential candidates and test their participation on signal transduction in an amino acids restricted e…
Undernutrition is still a recurrent nutritional problem in low-income or middle-income countries, affecting approximately 151 million children and being responsible for 45% of deaths in children under 5 years of age worldwide. It is known that metabolic-adaptive responses resulting from protein undernutrition contribute to the development of non-communicable chronic diseases, such as non-…
(Only some records are available in English at this moment)
(Only some records are available in English at this moment)
Malnutrition is a metabolic disorder that affects about 795 million individuals around the globe, resulting from the reduction in energy or nutritional intake in a given phase of life. It is well known that nutritional deficiency during development and maturation generates disturbances in communication, biogenesis and mitochondrial function in different rodent and human tissues, leading t…
Type 2 diabetes is an epidemic disease worldwide characterized by impaired insulin action and secretion in tissues and pancreatic ² cells, respectively. The pancreatic ± cell is also disrupted during the course of type 2 diabetes development. Bile acids are cholesterol-derived molecules, which had beneficial effects upon carbohydrate metabolism. In this context, the taurine conjugated bil…
Circadian rhythm is an adaptative mechanism that prepares the organism to respond to chances in environmental conditions. In mammals, the biological clock is generated endogenously in the suprachiasmatic nucleus of the hypothalamus, and the light is one of the most important synchronizer of this circadian system. Disruption of the circadian rhythm, by exposure to light at night, due shift…
(Only some records are available in English at this moment)
| 4 / 4 | Ongoing research grants |
| 12 / 7 | Completed research grants |
| 5 / 5 | Ongoing scholarships in Brazil |
| 54 / 28 | Completed scholarships in Brazil |
| 8 / 8 | Completed scholarships abroad |
| 83 / 52 | All research grants and scholarships |
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